Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Pippa L Pugh"'
Autor:
A. J. Hunter, Jane E. Cluderay, J. Latcham, Christian Heidbreder, Pippa L Pugh, Jon T. Brown, Charlie Reavill, Lee A. Dawson, Ceri H. Davies, Evelyn Grau, Susan J. Pickering, G Brown, Claire S. Shilliam, Barry Crook, A Howarth, Panida Hemmati, Zoe A. Hughes, Derek C. Rogers, Guillaume J. Hervieu, Stephen M. Harrison, Peter R. Maycox
Publikováno v:
Molecular and Cellular Neuroscience. 24:1170-1179
Several psychiatric diseases, including schizophrenia, are thought to have a developmental aetiology, but to date no clear link has been made between psychiatric disease and a specific developmental process. LPA1 is a Gi-coupled seven transmembrane r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f5ca71824413304196e63bb4298e03
https://doi.org/10.1016/j.mcn.2003.09.001
https://doi.org/10.1016/j.mcn.2003.09.001
Autor:
Graham J. Riley, Neil Upton, Lee A. Dawson, Douglas R Smith, Christian Heidbreder, Ciaran M. Regan, Tania O. Stean, David Sunter, Alan R. Atkins, Warren D. Hirst, Andrew G. Foley, Steven Mark Bromidge, Pippa L Pugh, Stephen Frederik SmithKline Beecham Phar Moss, Sarah Bartlett, Derek C. Rogers, Laurent P. Lacroix
Publikováno v:
European journal of pharmacology. 553(1-3)
SB-399885 (N-[3,5-dichloro-2-(methoxy)phenyl]-4-(methoxy)-3-(1-piperazinyl)benzenesulfonamide) has high affinity for human recombinant and native 5-HT(6) receptors, with pK(i) values 9.11+/-0.03 and 9.02+/-0.05, respectively and is a potent competiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1e5f0f38a3c35d5b55abd4f9d6b3512
https://pubmed.ncbi.nlm.nih.gov/17069795
https://pubmed.ncbi.nlm.nih.gov/17069795
Autor:
Panida Winter, Neil Upton, Alex J. Harper, Lee A. Dawson, Steve Mark Harrison, Julie Hawkins, M. Isabel Gonzalez, Pippa L Pugh, Menelas N. Pangalos, Zoe A. Hughes, Claire S. Shilliam, Evelyn Grau, Colin Dingwall, Graham Duddy
Publikováno v:
Molecular and cellular neurosciences. 24(3)
BACE1 is a key enzyme in the generation of Abeta, the major component of senile plaques in the brains of Alzheimer's disease patients. We have generated transgenic mice expressing human BACE1 with the Cam Kinase II promoter driving neuronal-specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a97c4d165cf40b66c88fb84a5746de9
https://pubmed.ncbi.nlm.nih.gov/14664815
https://pubmed.ncbi.nlm.nih.gov/14664815