Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Pippa J. Tyrrell"'
Autor:
Rachael M. Hunter, Naomi J. Fulop, Ruth J. Boaden, Christopher McKevitt, Catherine Perry, Angus I. G. Ramsay, Anthony G. Rudd, Simon J. Turner, Pippa J. Tyrrell, Charles D. A. Wolfe, Stephen Morris
Publikováno v:
Health Research Policy and Systems, Vol 16, Iss 1, Pp 1-14 (2018)
Abstract Background The economic implications of major system change are an important component of the decision to implement health service reconfigurations. Little is known about how best to report the results of economic evaluations of major system
Externí odkaz:
https://doaj.org/article/8a04e6e9f3bf4fb28327429af2658f81
Autor:
Catherine Perry, Katy Rothwell, Pippa J. Tyrrell, Emma Patchwood, Audrey Bowen, Kate Woodward-Nutt
Publikováno v:
Clinical Rehabilitation
Patchwood, E, Woodward-Nutt, K, Rothwell, K, Perry, C, Tyrrell, P & Bowen, A 2020, ' Six month reviews for stroke survivors: A study of the modified Greater Manchester Stroke Assessment Tool (GMSAT) with care home residents ', Clinical Rehabilitation . https://doi.org/10.1177/0269215520912515
Patchwood, E, Woodward-Nutt, K, Rothwell, K, Perry, C, Tyrrell, P & Bowen, A 2020, ' Six month reviews for stroke survivors: A study of the modified Greater Manchester Stroke Assessment Tool (GMSAT) with care home residents ', Clinical Rehabilitation . https://doi.org/10.1177/0269215520912515
Objectives: To explore the feasibility of using a stroke-specific toolkit for six-month post-stroke reviews in care homes to identify unmet needs and actions. Design: An observational study including qualitative interviews to explore the process and
Autor:
Anand Dixit, Arshad Majid, Diederik Bulters, Nick S. Ward, Paul Stroemer, Kenneth Pollock, Laurence Dunn, Mark Willmot, John Sinden, Pippa J. Tyrrell, Philip M.W. Bath, Keith W. Muir, Nikola Sprigg, Julian Howell
Publikováno v:
Journal of Neurology, Neurosurgery, and Psychiatry
BackgroundHuman neural stem cell implantation may offer improved recovery from stroke. We investigated the feasibility of intracerebral implantation of the allogeneic human neural stem cell line CTX0E03 in the subacute—chronic recovery phase of str
Autor:
Nancy J. Rothwell, Calvin Heal, Craig J. Smith, Stephen J. Hopkins, Karen Hopkins, Andy Vail, Pippa J. Tyrrell, Adrian R Parry-Jones, Stuart M. Allan, Sylvia Scarth, Sharon Hulme, Margaret E. Hoadley
Publikováno v:
Smith, C J, Hulme, S, Vail, A, Heal, C, Parry-Jones, A R, Scarth, S, Hopkins, K, Hoadley, M, Allan, S M, Rothwell, N J, Hopkins, S J & Tyrrell, P J 2018, ' SCIL-STROKE (Subcutaneous Interleukin-1 Receptor Antagonist in Ischemic Stroke) : A Randomized Controlled Phase 2 Trial ', Stroke, vol. 49, no. 5, pp. 1210-1216 . https://doi.org/10.1161/STROKEAHA.118.020750
Background and Purpose— The proinflammatory cytokine IL-1 (interleukin-1) has a deleterious role in cerebral ischemia, which is attenuated by IL-1 receptor antagonist (IL-1Ra). IL-1 induces peripheral inflammatory mediators, such as interleukin-6,
Autor:
Esme Worthington, Pippa J. Tyrrell, Louise Hawkins, Avril Drummond, Nadina B. Lincoln, Amit K Mistri, Nick S. Ward, Nikola Sprigg
Publikováno v:
Topics in Stroke Rehabilitation. 24:592-596
Background: Post-stroke fatigue is common and disabling. Objectives: The aim of NotFAST was to examine factors associated with fatigue in stroke 3 survivors without depression, six months after stroke. Methods: Participants were recruited from four U
Autor:
Anthony Rudd, Ruth Boaden, Pippa J. Tyrrell, Angus I G Ramsay, Simon Turner, Naomi Fulop, Stephen Morris, Charles D.A. Wolfe, Catherine Perry, Christopher McKevitt, Rachael Hunter, Iliatha Papachristou
Publikováno v:
Fulop, N J, Ramsay, A IG, Hunter, R M, McKevitt, C, Perry, C, Turner, S J, Boaden, R, Papachristou, I, Rudd, A G, Tyrrell, P J, Wolfe, C DA & Morris, S 2019, ' Evaluation of reconfigurations of acute stroke services in different regions of England and lessons for implementation: a mixed-methods study ', Health Services and Delivery Research, vol. 7, no. 7, pp. 1-250 . https://doi.org/10.3310/hsdr07070
Health Services and Delivery Research, Vol 7, Iss 7 (2019)
Health Services and Delivery Research, Vol 7, Iss 7 (2019)
Background Centralising acute stroke services is an example of major system change (MSC). ‘Hub and spoke’ systems, consisting of a reduced number of services providing acute stroke care over the first 72 hours following a stroke (hubs), with a la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b99aabda16d5fbb352d9cfc49356722
https://doi.org/10.3310/hsdr07070
https://doi.org/10.3310/hsdr07070
Autor:
Catherine Perry, Simon Turner, Naomi Fulop, Pippa J. Tyrrell, Stephen Morris, Christopher McKevitt, Rachael Hunter, Lizz Paley, Charles D.A. Wolfe, Ruth Boaden, Anthony Rudd, Angus I G Ramsay
Publikováno v:
Morris, S, Ramsay, A I G, Boaden, R J, Hunter, R M, McKevitt, C, Paley, L, Perry, C, Rudd, A G, Turner, S J, Tyrrell, P J, Wolfe, C D A & Fulop, N J 2019, ' Impact and sustainability of centralising acute stroke services in English metropolitan areas : Retrospective analysis of hospital episode statistics and stroke national audit data ', BMJ (Online), vol. 364, no. 0, l1 . https://doi.org/10.1136/bmj.l1
Morris, S, Ramsay, A I G, Boaden, R J, Hunter, R M, Mckevitt, C, Paley, L, Perry, C, Rudd, A G, Turner, S J, Tyrrell, P J, Wolfe, C D A & Fulop, N J 2019, ' Impact and sustainability of centralising acute stroke services in English metropolitan areas: retrospective analysis of hospital episode statistics and stroke national audit data ', Bmj, vol. 364, l1 . https://doi.org/10.1136/bmj.l1
The BMJ
Morris, S, Ramsay, A I G, Boaden, R J, Hunter, R M, Mckevitt, C, Paley, L, Perry, C, Rudd, A G, Turner, S J, Tyrrell, P J, Wolfe, C D A & Fulop, N J 2019, ' Impact and sustainability of centralising acute stroke services in English metropolitan areas: retrospective analysis of hospital episode statistics and stroke national audit data ', Bmj, vol. 364, l1 . https://doi.org/10.1136/bmj.l1
The BMJ
Objectives To investigate whether further centralisation of acute stroke services in Greater Manchester in 2015 was associated with changes in outcomes and whether the effects of centralisation of acute stroke services in London in 2010 were sustaine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e00e69a471b7bfc9a0a47cdde3a49e67
https://kclpure.kcl.ac.uk/ws/files/146279864/Impact_and_sustainability_of_centralising_acute_stroke_MCKEWITT_Published23January2019_GOLD_VoR_CC_BY_NC_.pdf
https://kclpure.kcl.ac.uk/ws/files/146279864/Impact_and_sustainability_of_centralising_acute_stroke_MCKEWITT_Published23January2019_GOLD_VoR_CC_BY_NC_.pdf
Autor:
Nancy J. Rothwell, Stephen J. Hopkins, Sharon Hulme, Kayode Ogungbenro, Pippa J. Tyrrell, James Galea
Publikováno v:
Journal of Pharmacokinetics and Pharmacodynamics. 43:1-12
Interleukin-1 receptor antagonist, a naturally-occurring antagonist to the pro-inflammatory cytokine Interleukin-1, is already in clinical use. In experimental models of stroke, Interleukin-1 receptor antagonist in cerebrospinal fluid has been associ
Autor:
Christopher McKevitt, Stephen Morris, Rachael Hunter, Simon Turner, Anthony Rudd, Alex Hoffman, Charles D.A. Wolfe, Nanik Pursani, Catherine Perry, Angus I G Ramsay, Naomi Fulop, Pippa J. Tyrrell, Ruth Boaden
Publikováno v:
Stroke; a Journal of Cerebral Circulation
Ramsay, A I G, Morris, S, Hoffman, A, Hunter, R M, Boaden, R, McKevitt, C, Perry, C, Pursani, N, Rudd, A G, Turner, S J, Tyrrell, P J, Wolfe, C D A & Fulop, N J 2015, ' Effects of centralizing acute stroke services on stroke care provision in two large metropolitan areas in England ', Stroke, vol. 46, no. 8, pp. 2244-2251 . https://doi.org/10.1161/STROKEAHA.115.009723
Ramsay, A I G, Morris, S, Hoffman, A, Hunter, R M, Boaden, R, McKevitt, C, Perry, C, Pursani, N, Rudd, A G, Turner, S J, Tyrrell, P J, Wolfe, C D A & Fulop, N J 2015, ' Effects of centralizing acute stroke services on stroke care provision in two large metropolitan areas in England ', Stroke, vol. 46, no. 8, pp. 2244-2251 . https://doi.org/10.1161/STROKEAHA.115.009723
Supplemental Digital Content is available in the text.
Background and Purpose— In 2010, Greater Manchester and London centralized acute stroke care into hyperacute units (Greater Manchester=3, London=8), with additional units providing ongoing
Background and Purpose— In 2010, Greater Manchester and London centralized acute stroke care into hyperacute units (Greater Manchester=3, London=8), with additional units providing ongoing
Autor:
Pippa J. Tyrrell, Mark Woodhead, Diederik van de Beek, Stephen J. Hopkins, Mario Di Napoli, Lalit Kalra, Javier Garau, Craig J. Smith, Amit Kishore, Joan Montaner, Andy Vail, Anthony Rudd, Peter Langhorne, Christine Roffe, Andreas Meisel, Ángel Chamorro
Publikováno v:
Stroke; a journal of cerebral circulation. 46(5):1202-1209
Background and Purpose— Diagnosis of pneumonia complicating stroke is challenging, and there are currently no consensus diagnostic criteria. As a first step in developing such consensus-based diagnostic criteria, we undertook a systematic review to