Zobrazeno 1 - 10 of 73 pro vyhledávání: '"Piplani Sakshi"'
1
Report
Computationally repurposed drugs and natural products against RNA dependent RNA polymerase as potential COVID-19 therapies
Autor: Piplani, Sakshi, Singh, Puneet, Winkler, David A., Petrovsky, Nikolai
For fast development of COVID-19, it is only feasible to use drugs (off label use) or approved natural products that are already registered or been assessed for safety in previous human trials. These agents can be quickly assessed in COVID-19 patient
Externí odkaz: http://arxiv.org/abs/2011.14241
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2
Report
Computational screening of repurposed drugs and natural products against SARS-Cov-2 main protease (Mpro) as potential COVID-19 therapies
Autor: Piplani, Sakshi, Singh, Puneet, Petrovsky, Nikolai, Winkler, David A.
There remains an urgent need to identify existing drugs that might be suitable for treating patients suffering from COVID-19 infection. Drugs rarely act at a single molecular target, with off target effects often being responsible for undesirable sid
Externí odkaz: http://arxiv.org/abs/2009.00744
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3
Report
In silico comparison of spike protein-ACE2 binding affinities across species; significance for the possible origin of the SARS-CoV-2 virus
Autor: Piplani, Sakshi, Singh, Puneet Kumar, Winkler, David A., Petrovsky, Nikolai
Publikováno v: Scientific Reports. 2021 Jun 24;11(1):13063. PMID: 34168168
The devastating impact of the COVID-19 pandemic caused by SARS coronavirus 2 (SARS CoV 2) has raised important questions about viral origin, mechanisms of zoonotic transfer to humans, whether companion or commercial animals can act as reservoirs for
Externí odkaz: http://arxiv.org/abs/2005.06199
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4
Akademický článek
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5
Akademický článek
Identifying SARS-CoV-2 Drugs Binding to the Spike Fatty Acid Binding Pocket Using In Silico Docking and Molecular Dynamics.
Autor: Piplani, Sakshi1,2 (AUTHOR), Singh, Puneet1,2 (AUTHOR), Petrovsky, Nikolai1,2 (AUTHOR) nikolai.petrovsky@flinders.edu.au, Winkler, David A.3,4,5 (AUTHOR)
Publikováno v: International Journal of Molecular Sciences. Feb2023, Vol. 24 Issue 4, p4192. 17p.
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6
Akademický článek
Potential COVID-19 Therapies from Computational Repurposing of Drugs and Natural Products against the SARS-CoV-2 Helicase.
Autor: Piplani, Sakshi1 (AUTHOR) sakshi.piplani@flinders.edu.au, Singh, Puneet1 (AUTHOR) puneet.singh@flinders.edu.au, Winkler, David A.2,3,4 (AUTHOR) d.winkler@latrobe.edu.au, Petrovsky, Nikolai1,5 (AUTHOR) nikolai.petrovsky@flinders.edu.au
Publikováno v: International Journal of Molecular Sciences. Jul2022, Vol. 23 Issue 14, p7704-7704. 18p.
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9
Akademický článek
In silico comparison of SARS-CoV-2 spike protein-ACE2 binding affinities across species and implications for virus origin.
Autor: Piplani, Sakshi1,2, Singh, Puneet Kumar2, Winkler, David A.3,4,5 d.winkler@latrobe.edu.au, Petrovsky, Nikolai1,2 nikolai.petrovsky@flinders.edu.au
Publikováno v: Scientific Reports. 6/24/2021, Vol. 11 Issue 1, p1-13. 13p.
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10
Akademický článek
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