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Akademický článek
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Apoptosis induction is a common therapeutic approach. However, many cancer cells are resistant to apoptotic death and alternative cell death pathways including pyroptosis and necroptosis need to be triggered. At the same time, danger signals that inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::fe004ff8b3c1e77a44453b5a245ad9a3
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3100319
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3100319
The serine/threonine kinase mechanistic target of rapamycin (mTOR) plays a pivotal role in the regulation of cell proliferation, survival, and motility in response to availability of energy and nutrients as well as mitogens. The mTOR signaling axis r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::ac3b07b1c94292ab1ed08fd08d7f9e75
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2980545
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2980545
The combination of Resminostat (HDACi) and Ruxolitinib (JAKi) exerted cytotoxic effects and inhibited proliferation of CTCL cell lines (MyLa, SeAx) in previously published work. A xenograft tumor formation was produced by implanting the MyLa or SeAx
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::82e6e1049df6b05de4a12f56b8208e0b
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3076842
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3076842
The transcriptional co-activators Yes-associated protein 1/transcriptional co-activator with PDZ-binding motif (YAP/TAZ) have emerged as significant regulators of a wide variety of cellular and organ functions with impact in early embryonic developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::29c4a27b2f586053122e4f9e9802083a
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2996905
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2996905
Craniosynostosis is the premature fusion of skull sutures and has a severe pathological impact on childrens’ life. Mechanical forces are capable of triggering biological responses in bone cells and regulate osteoblastogenesis in cranial sutures, le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::2b8619ce42e61d42f23426e92d0c1dab
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3076886
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3076886
Parkinson’s disease (PD) is the second most common neurodegenerative disorder with an unclear etiology and no disease-modifying treatment to date. PD is considered a multifactorial disease, since both genetic and environmental factors contribute to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::6c531bc6eb3f12f9605eb424e23333cf
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2996881
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2996881
Gliomas portray a large and heterogeneous group of CNS tumors, encompassing a wide range of low-to high-grade tumors, as defined by histological and molecular characteristics. The identification of signature mutations and other molecular abnormalitie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::e2db8c1d82eb4569438dd389cd4e9bb0
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3219735
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3219735
Autor:
Plemmenos, G. Piperi, C.
Advanced Glycation End Products (AGEs), the products of the non-enzymatic oxidation of proteins, nucleic acids, and lipids, are accumulated in periodontal tissues under hyperglycemic conditions such as Diabetes Mellitus (DM) and are responsible for s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::108673ae52d16fc254a4c83b930a875c
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3058358
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3058358