Principles and Procedures for Assessment of Acute Toxicity Incorporating In Silico Methods.

Autor: Zwickl CM; Transendix LLC, Indianapolis, IN 46229, USA., Graham J; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Jolly R; Eli Lilly and Company, Indianapolis, IN 46285, USA., Bassan A; Innovatune srl, Via Giulio Zanon 130/D, 35129 Padova, Italy., Ahlberg E; Universal Prediction AB, Gothenburg, Sweden.; Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden., Amberg A; Sanofi, R&D Preclinical Safety Frankfurt, Industriepark Hoechst, D-65926 Frankfurt am Main, Germany., Anger LT; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Barton-Maclaren T; Healthy Environments and Consumer Safety Branch, Health Canada / Government of Canada., Beilke L; Toxicology Solutions, Inc., 10531 4S Commons Dr. #594, San Diego, CA 92127, USA., Bellion P; Boehringer Ingelheim Animal Health, Binger Str. 128, 55216 Ingelheim am Rhein, Germany., Brigo A; Roche Pharmaceutical Research & Early Development, Roche Innovation Center Basel, Grenzacherstrasse 124, 4070, Basel, Switzerland., Cronin MTD; Liverpool John Moores University, Liverpool, L3 3AF, UK., Custer L; Bristol Myers-Squibb, New Brunswick, NJ, USA., Devlin A; FDA Center for Drug Evaluation and Research, Silver Spring, MD 20993, USA., Burleigh-Flayers H; PPG Industries, Monroeville, PA 15146, USA., Fish T; Nelson Laboratories, Salt Lake City, Utah, USA., Glover K; US Army, DEVCOM Chemical Biological Center., Glowienke S; Novartis, Basel, Switzerland., Gromek K; Glaxo Smith-Kline., Jones D; MHRA, 10 South Colonnade, Canary Wharf, London E14 4PU., Karmaus A; Integrated Laboratory Systems, LLC, Morrisville, NC, USA., Kemper R; Nuvalent, Cambridge, MA 02142, USA., Piparo EL; Chemical Food Safety Group, Nestlé Research, Lausanne, Switzerland., Madia F; European Commission, Joint Research Centre (JRC), Ispra, Italy., Martin M; Pfizer., Masuda-Herrera M; Gilead Sciences., McAtee B; PPG Industries, Monroeville, PA 15146, USA., Mestre J; IMIM Institut Hospital Del Mar d'Investigacions Mèdiques and Universitat Pompeu Fabra, Doctor Aiguader 88, Parc de Recerca Biomèdica, 08003 Barcelona, Spain.; Chemotargets SL, Baldiri Reixac 4, Parc Científic de Barcelona, 08028 Barcelona, Spain., Milchak L; 3M Company, St. Paul, MN., Moudgal C; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Mumtaz M; Office of the Associate Director for Science, Agency for Toxic Substances and Disease Registry, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA., Muster W; Roche Pharmaceutical Research & Early Development, Roche Innovation Center Basel, Grenzacherstrasse 124, 4070, Basel, Switzerland., Neilson L; Japan Tobacco International., Patlewicz G; Centre for Computational Toxicology and Exposure (CCTE), US Environmental Protection Agency, Research Triangle Park, NC, USA., Paulino A; Oro Agri Europe, S.A., Roncaglioni A; Laboratory of Environmental Chemistry and Toxicology, Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy., Ruiz P; Centers for Disease Control and Prevention (CDC), Atlanta, GA 30341, USA., Suarez D; FSTox Consulting LTD, 2 Brooks Road Raunds Wellingborough NN9 6NS., Szabo DT; PPG Industries, Monroeville, PA 15146, USA., Valentin JP; UCB-Biopharma SRL, Development Science, Avenue de l'industrie, Braine l'Alleud, Wallonia, Belgium., Vardakou I; British American Tobacco (Investments) Ltd., R&D Centre, Southampton, Hampshire SO15 8TL, UK., Woolley D; ForthTox Limited, Linlithgow, EH49 7YU, UK., Myatt G; Instem, 1393 Dublin Rd, Columbus, OH 43215, USA.

Publikováno v: Computational toxicology (Amsterdam, Netherlands) [Comput Toxicol] 2022 Nov; Vol. 24. Date of Electronic Publication: 2022 Jul 14.