Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Piotr Rózga"'
Progress in the field of pharmacy, closely related with the mutual stimulation of natural sciences and new technologies available to researchers, has been so rapid over the last few decades that it has begun to cause problems at the level of definiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51375c81f3f95cd6cf8c10c66ef27a58
https://ruj.uj.edu.pl/xmlui/handle/item/257171
https://ruj.uj.edu.pl/xmlui/handle/item/257171
Autor:
Marcin Cybulski, Bartłomiej Żerek, Katarzyna Sidoryk, Piotr Rózga, Marta Świtalska, Iwona Bujak, Joanna Wietrzyk, Łukasz Kaczmarek
Publikováno v:
Medicinal Chemistry Research
An optimization of the guanidylation process by verifying the efficacy of common guanylation reagents in order to obtain the guanidine derivatives of indolo[2,3-b]quinoline has been performed. As a result, a high-yield procedure using N,N′-di-Boc-N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd797ee6ca3de69d300893b0212652b
https://doi.org/10.1007/s00044-017-2028-1
https://doi.org/10.1007/s00044-017-2028-1
Autor:
Bogna Badyra, Anna Pieczykolan, Damian Kloska, Michal Szymanik, Katarzyna Bukato, Olga Zolnierkiewicz, Aleksandra Kopacz, Albert Jaworski, Anna Molga‐Kaczmarska, Sebastian Pawlak, Marta Targosz-Korecka, Neli Kachamakova-Trojanowska, Anna Grochot-Przeczek, Jerzy Pieczykolan, Katarzyna Poleszak, Marlena Galazka, Alicja Jozkowicz, Bartlomiej Zerek, Piotr Rózga, Malgorzata Teska-Kaminska
Publikováno v:
International journal of cancerReferences. 147(4)
Targeting of the TRAIL-DR4/5 pathway was proposed as a promising approach for specific induction of apoptosis in cancer cells. Clinical trials, however, showed inadequate efficiency of TRAIL as a monotherapy. It is a widely held view that the applica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8cd0358b596bf579bf0e4e724e33c6
https://pubmed.ncbi.nlm.nih.gov/31863596
https://pubmed.ncbi.nlm.nih.gov/31863596
Autor:
Anna Pieczykolan, Katarzyna Bukato, Sebastian Pawlak, Katarzyna Poleszak, Maciej Masłyk, Albert Jaworski, Konrad Kubiński, Marlena Gałązka, Jerzy Pieczykolan, Wojciech Strozek, Piotr Rózga, Rafal Zielinski, Malgorzata Teska-Kaminska, Michal Szymanik, Bartłomiej Żerek, Robert Świder
Publikováno v:
Investigational new drugs. 32(6)
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and its receptors became promising molecules for selective targeting of tumor cells without affecting normal tissue. Unfortunately, cancer cells have developed a number of mechanisms tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb64508a340c32d5ed0dfcdadde6cd8e
https://pubmed.ncbi.nlm.nih.gov/25182378
https://pubmed.ncbi.nlm.nih.gov/25182378
Autor:
Marlena Galazka, Piotr Rózga, Malgorzata Teska-Kaminska, Wojciech Strozek, Jerzy Pieczykolan, Katarzyna Bukato, Sebastian Pawlak, Michal Szymanik, Albert Jaworski, Katarzyna Poleszak, Bartlomiej Zerek, Anna Pieczykolan
Publikováno v:
Cancer Research. 74:4471-4471
Although standard chemotherapy is still one of the most effective treatment for many types of cancer - often causes side effects. Chemotherapeutic agents primarily damage cancer cells with a rapidly dividing and growing profile, thereby also destroy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ebe21c249fa57591530f18b2469cdd8
https://doi.org/10.1158/1538-7445.am2014-4471
https://doi.org/10.1158/1538-7445.am2014-4471
Autor:
Marlena Galazka, Katarzyna Bukato, Sebastian Pawlak, Bartlomiej Zerek, Katarzyna Poleszak, Wojciech Strozek, Piotr Rózga, Malgorzata Teska-Kaminska, Anna Pieczykolan, Jerzy Pieczykolan, Albert Jaworski, Michal Szymanik
Publikováno v:
Cancer Research. 74:2773-2773
Background The tumor necrosis factor related apoptosis-inducing ligand (TRAIL/Apo2L) is a member of the TNF superfamily that initiates apoptosis of tumor cells through the activation of their death receptors. The ability of TRAIL to selectively induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::748f531dabc012fecaf9fd275f3917d8
https://doi.org/10.1158/1538-7445.am2014-2773
https://doi.org/10.1158/1538-7445.am2014-2773
Autor:
Jerzy Pieczykolan, Anna Pieczykolan, Karl R. Erlemann, Piotr Rózga, Sebastian Pawlak, Albert Jaworski, Szymanik Michal, Jacek Capala, Bartlomiej Zerek, Malgorzata Teska Kaminska
Publikováno v:
Cancer Research. 74:2600-2600
Angiogenesis, the process of new blood vessels formation, is essential for tumor growth and metastasis. Since tumors are unable to grow beyond a millimeter diameter in the absence of angiogenic factors, it was postulated that blocking of angiogenic f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25ed1eb82e07cc2f5f60890687d231d9
https://doi.org/10.1158/1538-7445.am2014-2600
https://doi.org/10.1158/1538-7445.am2014-2600
Autor:
Katarzyna Poleszak, Jerzy Pieczykolan, Katarzyna Bukato, Anna Pieczykolan, Sebastian Pawlak, Wojciech Strozek, Michal Szymanik, Albert Jaworski, Piotr Rózga, Malgorzata Teska-Kaminska, Marlena Galaska, Bartlomiej Zerek
Publikováno v:
Cancer Research. 74:3796-3796
Background Cancer growth and development is tightly related to both new vessels formation for tissue remodeling and inhibition of anti-apoptotic signals. Vascular endothelial growth factor (VEGF) is important for vascular development in physiological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a551eef3788ed7f82c1ad95fbb10075
https://doi.org/10.1158/1538-7445.am2014-3796
https://doi.org/10.1158/1538-7445.am2014-3796
Autor:
Marlena Galazka, Albert Jaworski, Bartlomiej Zerek, Lukasz Kutner, Katarzyna Wiciejowska, Wojciech Strozek, Michal Szymanik, Anna Pieczykolan, Piotr Rózga, Malgorzata Teska-Kaminska, Jerzy Pieczykolan, Sebastian Pawlak
Publikováno v:
Cancer Research. 73:5488-5488
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL/Apo2L) is a promising antitumor agent, but its clinical utility in human malignancies is limited by the resistance mechanism evolved in many cancers types, including overexpresion of anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ce34f081ba2d9136c005e1176837090
https://doi.org/10.1158/1538-7445.am2013-5488
https://doi.org/10.1158/1538-7445.am2013-5488
Autor:
Marlena Galazka, Piotr Rózga, Lukasz Kutner, Neli Kahmakowa Trojanowska, Bartlomiej Zerek, Jerzy Pieczykolan, Malgorzata Teska Kaminska, Katarzyna Wiciejowska, Wojciech Strozek, Sebastian Pawlak, Michal Szymanik, Albert Jaworski, Anna Pieczykolan, Anna Grochot Przeczek
Publikováno v:
Cancer Research. 73:5073-5073
One of the most important mechanisms of tumorgenesis is formation of new blood vessels and tissue remodeling. Vascular endothelial growth factor (VEGF) is one of the most important and widely studied proangiogenic factors, that has an important role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b759f33077862938701a878fd4a89747
https://doi.org/10.1158/1538-7445.am2013-5073
https://doi.org/10.1158/1538-7445.am2013-5073