Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Piotr Popik"'
Autor:
Piotr Popik, Ewelina Cyrano, Diana Piotrowska, Malgorzata Holuj, Joanna Golebiowska, Natalia Malikowska-Racia, Agnieszka Potasiewicz, Agnieszka Nikiforuk
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Traditional methods of rat social behavior assessment are extremely time-consuming and susceptible to the subjective biases. In contrast, novel digital techniques allow for rapid and objective measurements. This study sought to assess the feasibility
Externí odkaz:
https://doaj.org/article/be7c51615a5846f184bc09f5d99008ac
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract A wide body of evidence suggests a relationship between maternal immune activation (MIA) and neurodevelopmental disorders such as autism spectrum disorder (ASD). Since social and communicative deficits are included in the first diagnostic cr
Externí odkaz:
https://doaj.org/article/8f6c5401d24c494d8d125d12d2e55c6e
Autor:
Mikolaj Matloka, Sylwia Janowska, Piotr Pankiewicz, Sofiya Kokhanovska, Tomasz Kos, Małgorzata Hołuj, Izabela Rutkowska-Wlodarczyk, Krzysztof Abramski, Monika Janicka, Piotr Jakubowski, Maciej Świątkiewicz, Marlena Welniak-Kaminska, Joanna Hucz-Kalitowska, Paulina Dera, Lukasz Bojarski, Paweł Grieb, Piotr Popik, Maciej Wieczorek, Jerzy Pieczykolan
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Phosphodiesterase 10A (PDE10A) is expressed almost exclusively in the striatum and its inhibition is suggested to offer potential treatment in disorders associated with basal ganglia. We evaluated the selectivity, cytotoxicity, genotoxici
Externí odkaz:
https://doaj.org/article/d453e3c4687c448496b544e69c14dfd4
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Posttraumatic stress disorder (PTSD) has been associated with abnormal regulation of the hypothalamic-pituitary-adrenal gland axis (HPA). Women demonstrate a more robust HPA response and are twice as likely to develop PTSD than men. The role of sex h
Externí odkaz:
https://doaj.org/article/1fcd0e0f6d2344759f53d7d112e853c0
Autor:
Anton Bespalov, René Bernard, Anja Gilis, Björn Gerlach, Javier Guillén, Vincent Castagné, Isabel A Lefevre, Fiona Ducrey, Lee Monk, Sandrine Bongiovanni, Bruce Altevogt, María Arroyo-Araujo, Lior Bikovski, Natasja de Bruin, Esmeralda Castaños-Vélez, Alexander Dityatev, Christoph H Emmerich, Raafat Fares, Chantelle Ferland-Beckham, Christelle Froger-Colléaux, Valerie Gailus-Durner, Sabine M Hölter, Martine CJ Hofmann, Patricia Kabitzke, Martien JH Kas, Claudia Kurreck, Paul Moser, Malgorzata Pietraszek, Piotr Popik, Heidrun Potschka, Ernesto Prado Montes de Oca, Leonardo Restivo, Gernot Riedel, Merel Ritskes-Hoitinga, Janko Samardzic, Michael Schunn, Claudia Stöger, Vootele Voikar, Jan Vollert, Kimberley E Wever, Kathleen Wuyts, Malcolm R MacLeod, Ulrich Dirnagl, Thomas Steckler
Publikováno v:
eLife, Vol 10 (2021)
While high risk of failure is an inherent part of developing innovative therapies, it can be reduced by adherence to evidence-based rigorous research practices. Supported through the European Union’s Innovative Medicines Initiative, the EQIPD conso
Externí odkaz:
https://doaj.org/article/056d0e1179a847c792213de97e872285
Autor:
Kinga Gzielo, Agnieszka Potasiewicz, Ewa Litwa, Diana Piotrowska, Piotr Popik, Agnieszka Nikiforuk
Publikováno v:
Brain Sciences, Vol 11, Iss 3, p 344 (2021)
Prenatal maternal infection is associated with an increased risk of various neurodevelopmental disorders, including autism spectrum disorders (ASD). Maternal immune activation (MIA) can be experimentally induced by prenatal administration of polyinos
Externí odkaz:
https://doaj.org/article/2a0b614469774bf5bf641c0ec0beed2b
Autor:
Agnieszka Nikiforuk, Predrag Kalaba, Marija Ilic, Volker Korz, Vladimir Dragačević, Judith Wackerlig, Thierry Langer, Harald Höger, Joanna Golebiowska, Piotr Popik, Gert Lubec
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 11 (2017)
Reduced cognitive abilities are often characterized by an impairment of flexibility, i.e., the ability to switch from learned rules or categories that were important in certain contexts to different new modalities that rule the task. Drugs targeting
Externí odkaz:
https://doaj.org/article/8a6fb1a9aa7041c1b1baf84bc3560418
Autor:
Agnieszka Nikiforuk, Tomasz Kos, Katarzyna Fijał, Małgorzata Hołuj, Dominik Rafa, Piotr Popik
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66695 (2013)
A wide body of evidence suggests that 5-HT7 receptors are implicated in a variety of central nervous system functions, including control of learning and memory processes. According to recent preclinical data, the selective blockade of these receptors
Externí odkaz:
https://doaj.org/article/21e9ff20ed1249a4a22492713fa77bf0
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51959 (2012)
Emotions can bias human decisions- for example depressed or anxious people tend to make pessimistic judgements while those in positive affective states are often more optimistic. Several studies have reported that affect contingent judgement biases c
Externí odkaz:
https://doaj.org/article/a6d02947b17b46989d1e8d3546d74fbe
Social and cognitive dysfunctions are the most persistent symptoms of schizophrenia. Since oxytocin (OXT) is known to play a role in social functions and modulates cognitive processes, we investigated the effects of a novel, nonpeptide, selective OXT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::284413a018d7ac6bb089450ad972daa9
https://doi.org/10.1101/2023.05.24.542076
https://doi.org/10.1101/2023.05.24.542076