Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Piotr P. Stepien"'
Dedicated surveillance mechanism controls G-quadruplex forming non-coding RNAs in human mitochondria
Autor:
Zbigniew Pietras, Magdalena A. Wojcik, Lukasz S. Borowski, Maciej Szewczyk, Tomasz M. Kulinski, Dominik Cysewski, Piotr P. Stepien, Andrzej Dziembowski, Roman J. Szczesny
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
G-rich RNAs encoded in mitochondrial DNA are prone to form four-stranded structures called G-quadruplexes (G4s). Here the authors show using in vitro and in vivo approaches that GRSF1 promotes melting of G4 RNA structures in mtRNAs, thus leading to t
Externí odkaz:
https://doaj.org/article/ecae75cc636546cf9e7e85d311c81677
Autor:
Zbigniew Pietras, Magdalena A. Wojcik, Lukasz S. Borowski, Maciej Szewczyk, Tomasz M. Kulinski, Dominik Cysewski, Piotr P. Stepien, Andrzej Dziembowski, Roman J. Szczesny
Publikováno v:
Molecular & Cellular Oncology, Vol 5, Iss 6 (2018)
Transcription of the human mitochondrial genome produces a vast amount of non-coding antisense RNAs. These RNA species can form G-quadraplexes (G4), which affect their decay. We found that the mitochondrial degradosome, a complex of RNA helicase SUPV
Externí odkaz:
https://doaj.org/article/68a4455d506c46f09067bb904eb47092
Autor:
Piotr P. Stepien
Publikováno v:
Studia Iuridica. 77:174-183
The article is a review of housing cooperative law in the last 100 years. The aim is to approximate one of the limited real rights contained in article 244 of the Civil Code, a cooperative ownership right to a flat. Indication of the most important c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7eca4068637afd3acebd56d017dd3ed5
https://doi.org/10.5604/01.3001.0013.1873
https://doi.org/10.5604/01.3001.0013.1873
Publikováno v:
Molecular Neurobiology
Correct selection of the reference gene(s) is the most important step in gene expression analysis. The aims of this study were to identify and evaluate the panel of possible reference genes in neural stem cells (NSC), early neural progenitors (eNP) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84cd6982cdd10e2d41002d35e1bb73c0
http://europepmc.org/articles/PMC6728297
http://europepmc.org/articles/PMC6728297
Autor:
Monika Kolanowska, Piotr P. Stepien, Jacek Lenart, Justyna Augustyniak, Krystian Jazdzewski, Pawel Gaj, Leonora Buzanska
Publikováno v:
Molecular Neurobiology
Bezafibrate (BZ) regulates mitochondrial biogenesis by activation of PPAR’s receptors and enhancing the level of PGC-1α coactivator. In this report, we investigated the effect of BZ on the expression of genes (1) that are linked to different pathw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b421acbb49c77ec9b2f96fc1175b17
http://europepmc.org/articles/PMC6505510
http://europepmc.org/articles/PMC6505510
Dedicated surveillance mechanism controls G-quadruplex forming non-coding RNAs in human mitochondria
Autor:
Tomasz M. Kulinski, Piotr P. Stepien, Zbigniew Pietras, Magdalena A. Wojcik, Dominik Cysewski, Andrzej Dziembowski, Lukasz S. Borowski, Maciej Szewczyk, Roman J. Szczesny
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Nature Communications
Nature Communications
The GC skew in vertebrate mitochondrial genomes results in synthesis of RNAs that are prone to form G-quadruplexes (G4s). Such RNAs, although mostly non-coding, are transcribed at high rates and are degraded by an unknown mechanism. Here we describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aacf3071a377ce02ed789a616e29c7f
http://link.springer.com/article/10.1038/s41467-018-05007-9
http://link.springer.com/article/10.1038/s41467-018-05007-9
Publikováno v:
Biogerontology
Idebenone, the synthetic analog of coenzyme Q10 can improve electron transport in mitochondria. Therefore, it is used in the treatment of Alzheimer’s disease and other cognitive impairments. However, the mechanism of its action on neurodevelopment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cdc3c565b8a6a94d21fd4ddd97f1e4f
http://europepmc.org/articles/PMC5514205
http://europepmc.org/articles/PMC5514205
Autor:
Danek Elbaum, Przemysław Kowalik, Andrzej Sienkiewicz, Piotr P. Stepien, W. Paszkowicz, Krzysztof Fronc, Maciej Szewczyk, Jacek Szczytko, Mariusz Łapiński, Karolina Zajdel, Tomasz Wojciechowski, Kamil Sobczak, Grzegorz M. Wilczynski, Wojciech Zaleszczyk, Anna Borodziuk, Anna Konopka, Izabela Kamińska, Roman Minikayev, Andrzej Twardowski, Małgorzata Frontczak-Baniewicz, Jaroslaw Rybusinski, J. Mikulski, Bożena Sikora
Publikováno v:
Nanoscale. 9:14259-14271
Water-soluble upconversion nanoparticles (UCNPs), based on polyvinylpyrrolidone (PVP)-coated NaYF4:Er3+,Yb3+,Gd3+, with various concentrations of Gd3+ ions and relatively high upconversion efficiencies, were synthesized. The internalization and cytot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba7f2c33df26a72e62e61a39ed3abfb1
https://doi.org/10.1039/c7nr03705h
https://doi.org/10.1039/c7nr03705h
Autor:
Mariusz Łapiński, Izabela Kaminska, Rodrigo Barbosa Nunes, Małgorzata Frontczak-Baniewicz, Maciej Szewczyk, J. Mikulski, Danek Elbaum, Grzegorz Gruzeł, Mirosława Pawlyta, Paulo C. Morais, J. Szczepkowski, Roman Minikayev, Bożena Sikora, Tomasz Wojciechowski, Wlodzimierz Jastrzebski, Wojciech Paszkowicz, Piotr P. Stepien, E. Mosiniewicz-Szablewska, Paulo Eduardo Narcizo de Souza, Krzysztof Fronc, Fabiane H. Veiga-Souza, Karolina Zajdel, Andrzej Sienkiewicz, Przemysław Kowalik
Publikováno v:
RSC Advances. 7:30262-30273
Inorganic nanomaterials able to generate reactive oxygen species (ROS) are promising components for modern medical applications. Activated by near-infrared light, up-converting β-NaYF4 doped with Er3+–Yb3+ and Tm3+–Yb3+ pair ions nanoparticles (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69f51207ee52f7e6fbcc19d46d92333f
https://doi.org/10.1039/c6ra25383k
https://doi.org/10.1039/c6ra25383k
Autor:
Dawid Piątkowski, M. Mouawad, Jarosław Młyńczak, Wojciech Zaleszczyk, Izabela Kamińska, Krzysztof Fronc, Piotr P. Stepien, Sebastian Mackowski, W. Paszkowicz, Tomasz Wojciechowski, Roman Minikayev, Kamil Sobczak, Maciej Szewczyk, A. Siemiarczuk, Miron Kaliszewski, K. Ciszak, Bożena Sikora, Krzysztof Kopczynski, Piotr Dziawa, Mariusz Łapiński, Maksymilian Włodarski, Danek Elbaum
Publikováno v:
RSC Advances. 5:78361-78373
Upconverting Gd2O3 nanoparticles (NPs) doped 1% Er3+ and 18% Yb3+ permits one to perform optical imaging. Because of the presence of Gd3+ they are useful in MRI. The main challenge is to enhance the NPs upconversion efficiency. As a result of co-dopi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d746e3d5a2cefd15e206574b7bf8d197
https://doi.org/10.1039/c5ra11888c
https://doi.org/10.1039/c5ra11888c