The Role of Pharmacological Treatment in the Chemoreflex Modulation

Autor: Anna Langner-Hetmańczuk, Stanisław Tubek, Piotr Niewiński, Piotr Ponikowski

Publikováno v: Frontiers in Physiology, Vol 13 (2022)

From a physiological point of view, peripheral chemoreceptors (PCh) are the main sensors of hypoxia in mammals and are responsible for adaptation to hypoxic conditions. Their stimulation causes hyperventilation—to increase oxygen uptake and increas

Externí odkaz: https://doaj.org/article/223d28642e12449bb98d2bfea22463af

Contributors

Autor: Daniela Accorsi–Mendonça, David J. Adams, Andrew M. Allen, Marlies Alvarenga, Jeffrey L. Ardell, Amy C. Arnold, Jesse L. Ashton, Mark B. Badrov, Brennan A. Ballantyne, Emma N. Bardsley, Soledad Barez-Lopez, Susan M. Barman, Carolyn J. Barrett, Deborah Bauer, Christopher Bell, Alona Ben-Tal, Eduardo E. Benarroch, Italo Biaggioni, Katharina Brandl, Virginia L. Brooks, Amy E. Brown, Kirsteen N. Browning, Meredith Bryarly, Livia L. Camargo, Michael Camilleri, Preston J. Campbell, Marc G. Caron, Jason R. Carter, Mark W. Chapleau, Nisha Charkoudian, Gisela Chelimsky, Thomas C. Chelimsky, Pitcha Chompoopong, Victoria E. Claydon, Gilles Clément, Victor A. Convertino, Elizabeth A. Coon, Pietro Cortelli, Stephen N. Davis, André Diedrich, Donald J. DiPette, Debra I. Diz, Marcus J. Drake, Graeme Eisenhofer, Florent Elefteriou, Fernando Elijovich, Eva-Maria Elmenhorst, Brett A. English, Murray Esler, Rosemary Esler, Paul J. Fadel, John M. Fahrenholz, Alessandra Fanciulli, John Y. Fang, Robert D. Fealey, Nathanne S. Ferreira, Renato Filogonio, Gregory D. Fink, James P. Fisher, John S. Floras, Samuel J. Fountain, Qi Fu, Marat Fudim, Raffaello Furlan, Alfredo Gamboa, Emily M. Garland, Christopher H. Gibbons, Andrew Giritharan, David S. Goldstein, Diego A. Golombék, Elise P. Gomez-Sanchez, Celso E. Gomez-Sanchez, Robert M. Graham, Guido Grassi, Ian M. Greenlund, Blair P. Grubb, Alla Guekht, Sarah-Jane Guild, Ling Guo, Vsevolod V. Gurevich, Ralf Habermann, Joseph Hadaya, Maureen K. Hahn, Peter Hanna, Luke A. Henderson, Neil Herring, Max J. Hilz, Peter Hunter, Keith Hyland, Lauren A. Hyland, Edwin Kerry Jackson, Giris Jacob, Wilfrid Jänig, Nina Japundžić-Žigon, Carrie K. Jones, Karen M. Joos, Jens Jordan, William Joyce, Xenia Kaidonis, Horacio Kaufmann, David Kaye, Abdul Mannan Khan Minhas, Joyce S. Kim, Takeya Kitta, David D. Kline, Thomas Konecny, Natalie J. Koons, Ambrish Kumar, Cheryl L. Laffer, Andre H. Lagrange, Nora Laiken, Gavin Lambert, Elisabeth Lambert, Guillaume Lamotte, Jacques W.M. Lenders, Benjamin D. Levine, Fabian Leys, Ulrich Limper, Mabelle Lin, Eduardo Listik, Reid Longmuir, David A. Low, Phillip A. Low, James M. Luther, Vaughan G. Macefield, Benedito H. Machado, Maria-Bernadette Madel, Davide Martelli, Christopher J. Mathias, Michelle L. Mauermann, Robin M. McAllen, Fiona D. McBryde, Andrew McKeon, Michael J. McKinley, Clément Menuet, Douglas F. Milam, Marion C. Mohl, Johanna M. Montgomery, Davi J.A. Moraes, Shaun F. Morrison, David Murphy, Charles D. Nichols, Piotr Niewiński, Lucy Norcliffe-Kaufmann, Luis E. Okamoto, Mahyar Osanlouy, John W. Osborn, Viktor Oubaid, Jose-Alberto Palma, Christina Pamporaki, Brian A. Parsons, David J. Paterson, Julian F.R. Paton, Amanda C. Peltier, Umberto Pensato, Sean M. Peterson, Fenna T. Phibbs, Giulia Pierangeli, Jay D. Potts, Alejandro A. Rabinstein, Mohan K. Raizada, Satish R. Raj, Casey M. Rand, Heinz Reichmann, Calum Robertson, Rose Marie Robertson, Michael B. Robinson, Mohammed Ruzieh, Paola Sandroni, Takayuki Sato, Ernesto L. Schiffrin, Markus Schlaich, Ronald Schondorf, Harold D. Schultz, Michael M. Scott, Gino Seravalle, John R. Shannon, Abu Baker Sheikh, Cyndya A. Shibao, Kalyanam Shivkumar, Kamal Shouman, Timo Siepmann, Wolfgang Singer, Elias Soltani, Virend Somers, Aadhavi Sridharan, Nadia Stefanova, Julian Stewart, Lauren E. Stiles, Kenji Sunagawa, Jens Tank, Roland D. Thijs, Jakub Tomek, Rhian M. Touyz, Jennifer A. Tracy, R. Alberto Travagli, Bradley J. Undem, Nikhil Urs, Steven Vernino, Lauro C. Vianna, Daniel E. Vigo, Margaret A. Vizzard, Amr Wahba, Waqar Waheed, Han-Jun Wang, Tobias Wang, Qin Wang, Ruihao Wang, Debra E. Weese-Mayer, Gregor K. Wenning, Wouter Wieling, Kevin W. Williams, Ursula H. Winzer-Serhan, Scott Wood, Kai Lee Yap, Naoki Yoshimura, Kirill A. Zavalin, Dmitry Zhuravlev, Daniel B. Zoccal, Jasenka Zubcevic

Publikováno v: Primer on the Autonomic Nervous System ISBN: 9780323854924

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6bafd1601fa1262b19bc5727a98b1d87
https://doi.org/10.1016/b978-0-323-85492-4.01002-4

Assessment of baroreflex sensitivity has no prognostic value in contemporary, optimally managed patients with mild-to-moderate heart failure with reduced ejection fraction: a retrospective analysis of 5-year survival

Autor: Bartłomiej, Paleczny, Martyna, Olesińska-Mader, Agnieszka, Siennicka, Piotr, Niewiński, Krzysztof, Nowak, Agnieszka, Buldańczyk, Ewa A, Jankowska, Waldemar, Banasiak, Stephan, von Haehling, Beata, Ponikowska, Stefan D, Anker, Piotr, Ponikowski

Publikováno v: European journal of heart failure. 21(1)

We evaluated the prognostic value of cardiac baroreflex sensitivity (BRS) in contemporary, optimally treated patients with mild-to-moderate heart failure with reduced ejection fraction (HFrEF).Data from 97 patients with HFrEF (left ventricular ejecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::50896f4f01b9222d6bab40574feb4641
https://pubmed.ncbi.nlm.nih.gov/30468274

The effects of P2Y12 adenosine receptors’ inhibitors on central and peripheral chemoreflexes

Autor: Stanislaw Tubek, Piotr Niewinski, Anna Langner-Hetmanczuk, Maksym Jura, Wiktor Kuliczkowski, Krzysztof Reczuch, Piotr Ponikowski

Publikováno v: Frontiers in Physiology, Vol 14 (2023)

Introduction: The most common side effect of ticagrelor is dyspnea, which leads to premature withdrawal of this life-saving medication in 6.5% of patients. Increased chemoreceptors’ sensitivity was suggested as a possible pathophysiological explana

Externí odkaz: https://doaj.org/article/1927d4086e0a4d748448c22da4c5c7fa

Acute hyperoxia reveals tonic influence of peripheral chemoreceptors on systemic vascular resistance in heart failure patients

Autor: Stanislaw Tubek, Piotr Niewinski, Bartlomiej Paleczny, Anna Langner-Hetmanczuk, Waldemar Banasiak, Piotr Ponikowski

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)

Abstract Peripheral chemoreceptors’ (PCh) hyperactivity increases sympathetic tone. An augmented acute ventilatory response to hypoxia, being a marker of PCh oversensitivity, was also identified as a marker of poor prognosis in HF. However, not muc

Externí odkaz: https://doaj.org/article/ddecc1ff002b4c47a64c5d8ba721841b