Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Piotr Niedziejko"'
Autor:
Robert Koralewski, Michał Kowalski, Krzysztof Matyszewski, Sylwia Olejniczak, Piotr L. Sklepkiewicz, Michal Piotrowicz, Czestkowski Wojciech J, Michal Mlacki, Adam Golebiowski, Karolina Dzwonek, Barbara Dymek, Magdalena Salamon, Bartlomiej Borek, Piotr Niedziejko, Agnieszka Bartoszewicz, Marcin Nowotny, Agnieszka Zagozdzon, Mariusz Gruza, Agnieszka Napiorkowska-Gromadzka, Aneta Bartlomiejczak, Pawel Dobrzanski, Marzena Mazur, Gleb Andryianau, Magdalena Kania, Jakub Golab, Pluta Elzbieta, Karol Jedrzejczak, Witold Mozga, Marcin Mazurkiewicz, Tomasz Rejczak, Jacek Olczak, Sylwia Piasecka, Aleksandra Rymaszewska
Publikováno v:
Journal of Medicinal Chemistry. 63:15527-15540
Chitotriosidase (CHIT1) and acidic mammalian chitinase (AMCase) are the enzymatically active chitinases that have been implicated in the pathology of chronic lung diseases such as asthma and inters...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2dd9844a8fb40d1518481d781cdfd6d
https://doi.org/10.1021/acs.jmedchem.0c01179
https://doi.org/10.1021/acs.jmedchem.0c01179
Autor:
Robert, Koralewski, Barbara, Dymek, Marzena, Mazur, Piotr, Sklepkiewicz, Sylwia, Olejniczak, Wojciech, Czestkowski, Krzysztof, Matyszewski, Gleb, Andryianau, Piotr, Niedziejko, Michal, Kowalski, Mariusz, Gruza, Bartłomiej, Borek, Karol, Jedrzejczak, Agnieszka, Bartoszewicz, Elżbieta, Pluta, Aleksandra, Rymaszewska, Magdalena, Kania, Tomasz, Rejczak, Sylwia, Piasecka, Michal, Mlacki, Marcin, Mazurkiewicz, Michał, Piotrowicz, Magdalena, Salamon, Agnieszka, Zagozdzon, Agnieszka, Napiorkowska-Gromadzka, Aneta, Bartlomiejczak, Witold, Mozga, Paweł, Dobrzański, Karolina, Dzwonek, Jakub, Golab, Marcin, Nowotny, Jacek, Olczak, Adam, Golebiowski
Publikováno v:
Journal of medicinal chemistry. 63(24)
Chitotriosidase (CHIT1) and acidic mammalian chitinase (AMCase) are the enzymatically active chitinases that have been implicated in the pathology of chronic lung diseases such as asthma and interstitial lung diseases (ILDs), including idiopathic pul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b9418f8d294ee157abcdfd2a01099fe4
https://pubmed.ncbi.nlm.nih.gov/33078933
https://pubmed.ncbi.nlm.nih.gov/33078933
Autor:
Robert Koralewski, Gleb Andryianau, Krzysztof Matyszewski, Bartlomiej Borek, Pluta Elzbieta, Adam Golebiowski, Marcin Mazurkiewicz, Jakub Golab, Barbara Dymek, Piotr Niedziejko, Czestkowski Wojciech J, Michal Piotrowicz, Michał Kowalski, Sylwia Olejniczak, Marzena Mazur, Jacek Olczak, Agnieszka Zagozdzon, Filip Stefaniak, Karolina Dzwonek, Agnieszka Bartoszewicz, Mariusz Gruza, Magdalena Salamon
Publikováno v:
Bioorganic & Medicinal Chemistry Letters
This article describes our work towards the identification of a potent and selective inhibitor of mouse chitotriosidase (mCHIT1). A series of small molecule inhibitors of mCHIT1 and mAMCase have been developed from early lead compound 1 . Examination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::340f6f7ae7b7c75d35d3b35d53144a21
https://doi.org/10.1016/j.bmcl.2017.12.047
https://doi.org/10.1016/j.bmcl.2017.12.047
Publikováno v:
Tetrahedron: Asymmetry. 26:1083-1094
A series of novel epimeric arylmethanamine ligands were synthesized from l -proline. Both epimers were subsequently examined in the copper(II)-catalyzed asymmetric Henry reaction. Product yield and stereoselectivity up to 92% ee indicated that the (S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a9d2ab1622333f09a2ec17a25985c96
https://doi.org/10.1016/j.tetasy.2015.08.002
https://doi.org/10.1016/j.tetasy.2015.08.002
Publikováno v:
Tetrahedron: Asymmetry. 24:1435-1442
The synthesis of novel, enantiomerically pure C 2 -symmetrical hemiaminal ethers and diamines containing piperazine core is presented. The key steps of the synthesis involve the dimerization of an in situ generated α-amino aldehyde into the correspo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49ec2e76f83fb3c9f77f40ecc530c602
https://doi.org/10.1016/j.tetasy.2013.09.011
https://doi.org/10.1016/j.tetasy.2013.09.011
Publikováno v:
ChemInform. 47
A range of L-proline derived diamines are synthesized and the 4-methoxyphenyl derivative (PRD) is employed as optimal ligand for the Cu(II)-catalyzed Henry reaction of aliphatic and aromatic aldehydes with nitromethane.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2f16899310710c43539e368d3fce5ff
https://doi.org/10.1002/chin.201608070
https://doi.org/10.1002/chin.201608070
Publikováno v:
ChemInform. 45
Novel diamine ligands with spiro indane-2,2′-pyrrolidine scaffold were synthesized starting from Seebach’s oxazolidinone 6 and were subsequently employed in asymmetric Henry reaction. Following the initial experimental findings, further synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20011d9be9fc3d4a76c0db5073a32ca8
https://doi.org/10.1002/chin.201430027
https://doi.org/10.1002/chin.201430027
Publikováno v:
ChemInform. 45
The new C2-symmetric hemiacetal ligand (CSH) gives generally good results for the asymmetric benzoylation of meso-diols as well as for the Henry nitro aldol reaction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37c7d232c36133b376db36f2b420b841
https://doi.org/10.1002/chin.201417048
https://doi.org/10.1002/chin.201417048
Publikováno v:
The Journal of organic chemistry. 79(3)
Novel diamine ligands with spiro indane-2,2′-pyrrolidine scaffold were synthesized starting from Seebach’s oxazolidinone 6 and were subsequently employed in asymmetric Henry reaction. Following the initial experimental findings, further synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::672a8f255a02f1d3a79ad63840986641
https://pubmed.ncbi.nlm.nih.gov/24437641
https://pubmed.ncbi.nlm.nih.gov/24437641