Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Piotr Kazmierczak"'
Autor:
Clive P. Morgan, Hongyu Zhao, Meredith LeMasurier, Wei Xiong, Bifeng Pan, Piotr Kazmierczak, Matthew R. Avenarius, Michael Bateschell, Ruby Larisch, Anthony J. Ricci, Ulrich Müller, Peter G. Barr-Gillespie
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Hair cells of the inner ear transduce mechanical stimuli like sound or head movements into electrical signals, which are propagated to the central nervous system. The hair-cell mechanotransduction channel remains unidentified. We tested whether three
Externí odkaz:
https://doaj.org/article/d575ed1e6a8c4635817fbfe708a330e9
Autor:
Ulrich Müller, Anthony J. Ricci, Bifeng Pan, Peter G. Barr-Gillespie, Clive P Morgan, Michael Bateschell, Wei Xiong, Piotr Kazmierczak, Meredith LeMasurier, Matthew R. Avenarius, Ruby Larisch, Hongyu Zhao
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
Hair cells of the inner ear transduce mechanical stimuli like sound or head movements into electrical signals, which are propagated to the central nervous system. The hair-cell mechanotransduction channel remains unidentified. We tested whether three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d024774b8d190ba13e583cd567910cea
http://journal.frontiersin.org/article/10.3389/fncel.2018.00041/full
http://journal.frontiersin.org/article/10.3389/fncel.2018.00041/full
Autor:
Suzan L. Harris, Martin Schwander, Anthony W. Peng, Marcin Kazmierczak, Marc Lenoir, Prahar Shah, Jean-Luc Puel, Piotr Kazmierczak, Santos J. Franco
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 37(13)
Mutations in thePejvakin(PJVK) gene are thought to cause auditory neuropathy and hearing loss of cochlear origin by affecting noise-induced peroxisome proliferation in auditory hair cells and neurons. Here we demonstrate that loss of pejvakin in hair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b6fb63a41f1306de0573f42e255548
https://pubmed.ncbi.nlm.nih.gov/28209736
https://pubmed.ncbi.nlm.nih.gov/28209736
Autor:
Ulrich Müller, Piotr Kazmierczak
Publikováno v:
Trends in Neurosciences. 35:220-229
Animals use acoustic signals to communicate and to obtain information about their environment. The processing of acoustic signals is initiated at auditory sense organs, where mechanosensory hair cells convert sound-induced vibrations into electrical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca28569c0920ccf8a2c9d88c10e5bf26
https://doi.org/10.1016/j.tins.2011.10.007
https://doi.org/10.1016/j.tins.2011.10.007
Publikováno v:
Journal of Physiology and Biochemistry. 68:329-334
1-Methylnicotinamide (MNA) is a primary metabolite of nicotinamide recently proven to cause systemic increase in PGI(2) plasma levels in an unknown mechanism. Our present study was aimed at verifying whether the increased production of PGI(2), a vaso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4bbdd7bc3ab30c867193c6bebe24763
https://doi.org/10.1007/s13105-012-0144-4
https://doi.org/10.1007/s13105-012-0144-4
Publikováno v:
The Journal of Neuroscience. 30:11259-11269
Tip links are extracellular filaments that connect pairs of hair cell stereocilia and convey tension to mechanosensitive channels. Recent evidence suggests that tip links are formed by calcium-dependent interactions between the N-terminal domains of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af72f1fa8953731d174d1cefbd260869
https://doi.org/10.1523/jneurosci.1949-10.2010
https://doi.org/10.1523/jneurosci.1949-10.2010
Autor:
Peter Clark, Heather M. Elledge, Peter Kuhn, Ulrich Müller, Anand Kolatkar, Jeremiah S. Joseph, Piotr Kazmierczak
Publikováno v:
Proceedings of the National Academy of Sciences. 107:10708-10712
The cadherin superfamily encodes more than 100 receptors with diverse functions in tissue development and homeostasis. Classical cadherins mediate adhesion by binding interactions that depend on their N-terminal extracellular cadherin (EC) domains, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e85ee95169e6f786b4468e498d4d606c
https://doi.org/10.1073/pnas.1006284107
https://doi.org/10.1073/pnas.1006284107
Autor:
Rachel A. Dumont, Ulrich Müller, Peter G. Gillespie, Concepción Lillo, Edith Hintermann, Anna Sczaniecka, Takashi Sato, David S. Williams, Nicolas Grillet, Wei Xiong, Piotr Kazmierczak, Martin Schwander, Bechara Kachar, Anna Reynolds
Publikováno v:
Neuron. 62:375-387
SummaryIn hair cells, mechanotransduction channels are gated by tip links, the extracellular filaments that consist of cadherin 23 (CDH23) and protocadherin 15 (PCDH15) and connect the stereocilia of each hair cell. However, which molecules mediate c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3240830e4d9c84f844eb7a57aab32cd
https://doi.org/10.1016/j.neuron.2009.04.006
https://doi.org/10.1016/j.neuron.2009.04.006
Autor:
Peter Kuhn, Ulrich Müller, Lisa M. Tarantino, Andrea Lelli, Anna Sczaniecka, Wei Xiong, Bechara Kachar, Tim Wiltshire, Anand Kolatkar, Joshua Tokita, Heather M. Elledge, Jeffrey R. Holt, Martin Schwander, Piotr Kazmierczak
Publikováno v:
Proceedings of the National Academy of Sciences. 106:5252-5257
Deafness is the most common form of sensory impairment in humans and is frequently caused by single gene mutations. Interestingly, different mutations in a gene can cause syndromic and nonsyndromic forms of deafness, as well as progressive and age-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a01335c8a8d32373ef3bfbfd00c6cd63
https://doi.org/10.1073/pnas.0900691106
https://doi.org/10.1073/pnas.0900691106
Autor:
Ulrich Müller, Hirofumi Sakaguchi, Piotr Kazmierczak, Bechara Kachar, Ronald A. Milligan, Elizabeth M. Wilson-Kubalek, Joshua Tokita
Publikováno v:
Nature. 449:87-91
Hair cells of the inner ear are so-called because of the hair-like projections, or stereocilia, that protrude from their apical surface. Sound-induced stereocilial motion is thought to be coupled to mechanoelectrical transduction channels via the 'ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e07b36f3bdf9ebc472a36c2a6b6095
https://doi.org/10.1038/nature06091
https://doi.org/10.1038/nature06091