Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Piotr Kawczak"'
Autor:
Piotr Brzeziński, Igor Feszak, Beatriz Di Martino Ortiz, Sylwia Feszak, Piotr Kawczak, Tomasz Bączek
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1799 (2024)
Vulvar intraepithelial neoplasia, also known as VIN, is a non-invasive squamous lesion and precursor of squamous cell carcinoma (SCC) of the vulva. There is no screening test for vulvar intraepithelial neoplasia. Diagnosis of VIN is made clinically a
Externí odkaz:
https://doaj.org/article/b5d35c6d20bc4829b448acca5ad74e63
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 1059 (2024)
Vitamin A, an essential micronutrient, is integral to various biological processes crucial for organismal development and maintenance. Dietary sources of vitamin A encompass preformed retinol, retinyl esters, and provitamin A carotenoids. Retinoic ac
Externí odkaz:
https://doaj.org/article/6e82988f26654f9e814559ca8057ecbd
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 6, Pp 6665-6678 (2012)
Pharmacological and physicochemical classification of the furan and thiophene amide derivatives by multiple regression analysis and partial least square (PLS) based on semi-empirical ab initio molecular modeling studies and high-performance liquid ch
Externí odkaz:
https://doaj.org/article/0cb27472684e4f8797b2a137e86aa017
Publikováno v:
Current Computer-Aided Drug Design. 16:93-103
Background: Pharmacological and physicochemical classification of bases’ selected analogues of nucleic acids is proposed in the study. Objective: Structural parameters received by the PCM (Polarizable Continuum Model) with several types of calculat
Publikováno v:
Letters in Drug Design & Discovery. 17:214-225
Background: Nitro-derivatives of heterocyclic compounds were used as active agents against pathogenic microorganisms. A set of 4- and 5-nitroimidazole derivatives exhibiting antimicrobial activity was analyzed with the use of Quantitative Structure-A
Publikováno v:
Combinatorial Chemistry & High Throughput Screening. 22:97-112
Background: A set of β-lactam antibiotics, aminoglycoside antibiotics, and tetracycline antibiotics were proposed and analyzed with the use of Quantitative Structure-Activity Relationships (QSAR) method. Objective: The characterization of selected a
Publikováno v:
Medicinal Chemistry Research. 28:778-787
A group of sulfonamides exhibiting antimicrobial activity was analyzed with the application of quantitative structure–activity/property relationships method. The purpose of this study was to show the common and differentiating characteristics of th
Autor:
Krzesimir Ciura, Tomasz Bączek, Joanna Nowakowska, Piotr Kawczak, Adrian Szewczyk, Anna Rutecka
Publikováno v:
Journal of the Iranian Chemical Society. 16:1019-1027
The chromatographic properties for nine antipsychotic drugs: chlorpromazine, chlorprothixene, clozapine, quetiapine, perazine, perphenazine, prochlorperazine, promazine and trifluoperazine were studied using planar chromatography. Both C18-bonded sil
Publikováno v:
Acta Poloniae Pharmaceutica - Drug Research. 75:1447-1458
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 188
The development of high-throughput methods for the estimation of physicochemical and biological properties of drug candidates is highly desired in the pharmaceutical landscape. Affinity to plasma protein is one of the most important biological proper