Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Piotr J. Balwierz"'
Autor:
Ana R. López-Pérez, Piotr J. Balwierz, Boris Lenhard, Ferenc Muller, Fiona C. Wardle, Isabelle Manfroid, Marianne L. Voz, Bernard Peers
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Retinoic acid (RA) is a key signal for the specification of the pancreas. Still, the gene regulatory cascade triggered by RA in the endoderm remains poorly characterized. In this study, we investigated this regulatory network in zebrafish by
Externí odkaz:
https://doaj.org/article/850bfa32b31943dd9ae0d3bdc4010ac4
Autor:
Damir Baranasic, Matthias Hörtenhuber, Piotr J. Balwierz, Tobias Zehnder, Abdul Kadir Mukarram, Chirag Nepal, Csilla Várnai, Yavor Hadzhiev, Ada Jimenez-Gonzalez, Nan Li, Joseph Wragg, Fabio M. D’Orazio, Dorde Relic, Mikhail Pachkov, Noelia Díaz, Benjamín Hernández-Rodríguez, Zelin Chen, Marcus Stoiber, Michaël Dong, Irene Stevens, Samuel E. Ross, Anne Eagle, Ryan Martin, Oluwapelumi Obasaju, Sepand Rastegar, Alison C. McGarvey, Wolfgang Kopp, Emily Chambers, Dennis Wang, Hyejeong R. Kim, Rafael D. Acemel, Silvia Naranjo, Maciej Łapiński, Vanessa Chong, Sinnakaruppan Mathavan, Bernard Peers, Tatjana Sauka-Spengler, Martin Vingron, Piero Carninci, Uwe Ohler, Scott Allen Lacadie, Shawn M. Burgess, Cecilia Winata, Freek van Eeden, Juan M. Vaquerizas, José Luis Gómez-Skarmeta, Daria Onichtchouk, Ben James Brown, Ozren Bogdanovic, Erik van Nimwegen, Monte Westerfield, Fiona C. Wardle, Carsten O. Daub, Boris Lenhard, Ferenc Müller
Publikováno v:
Baranasic, D, Hörtenhuber, M, Balwierz, P J, Zehnder, T, Mukarram, A K, Nepal, C, Várnai, C, Hadzhiev, Y, Jimenez-Gonzalez, A, Li, N, Wragg, J, D’Orazio, F M, Relic, D, Pachkov, M, Díaz, N, Hernández-Rodríguez, B, Chen, Z, Stoiber, M, Dong, M, Stevens, I, Ross, S E, Eagle, A, Martin, R, Obasaju, O, Rastegar, S, McGarvey, A C, Kopp, W, Chambers, E, Wang, D, Kim, H R, Acemel, R D, Naranjo, S, Łapiński, M, Chong, V, Mathavan, S, Peers, B, Sauka-Spengler, T, Vingron, M, Carninci, P, Ohler, U, Lacadie, S A, Burgess, S M, Winata, C, van Eeden, F, Vaquerizas, J M, Gómez-Skarmeta, J L, Onichtchouk, D, Brown, B J, Bogdanovic, O, van Nimwegen, E, Westerfield, M, Wardle, F C, Daub, C O, Lenhard, B & Müller, F 2022, ' Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements ', Nature Genetics, vol. 54, no. 7, pp. 1037-1050 . https://doi.org/10.1038/s41588-022-01089-w
Nature Genetics, 54, 1037–1050
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Genetics, 54, 1037–1050
Digital.CSIC. Repositorio Institucional del CSIC
instname
14 pages, 8 figures, supplementary information https://doi.org/10.1038/s41588-022-01089-w.-- Data availability: Raw and aligned sequencing data are available at https://danio-code.zfin.org/dataExport/. The raw sequencing data produced for this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c9b0ff730aa047c825365d177a9878
https://edoc.unibas.ch/89500/
https://edoc.unibas.ch/89500/
Autor:
Ferenc Müller, Ana R. López-Pérez, Boris Lenhard, Bernard Peers, Marianne Voz, Isabelle Manfroid, Piotr J. Balwierz, Fiona C. Wardle
Retinoic acid (RA) is a key signal for the specification of the pancreas. Still, the gene regulatory cascade triggered by RA in the endoderm remains poorly characterized. In this study, we investigated this regulatory network in zebrafish by combinin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a64f3624db9a5651c42b428f8ff82322
https://doi.org/10.1101/2020.11.09.341016
https://doi.org/10.1101/2020.11.09.341016
Autor:
Yixuan Guo, Boris Lenhard, Ferenc Müller, Fabio M. D’Orazio, Juan M. Vaquerizas, Aleksandra Jasiulewicz, Benjamín Hernández-Rodríguez, Bradley R. Cairns, Piotr J. Balwierz
SUMMARYIn many animal models, primordial germ cell (PGC) development depends on maternally-deposited germ plasm to avoid somatic cell fate. Here, we show that PGCs respond to regulatory information from the germ plasm in two distinct phases and mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b64037fe202b8e928646f7f6922f47
https://doi.org/10.1101/2020.01.12.903336
https://doi.org/10.1101/2020.01.12.903336
Autor:
Joseph W. Wragg, Bernard Peers, Jesper B. Andersen, Estefanía Tarifeño-Saldivia, Ferenc Müller, Piotr J. Balwierz, Piero Carninci, Boris Lenhard, Yavor Hadzhiev, Chirag Nepal, Ryan Cardenas, Ana-Maria Suzuki
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nepal, C, Hadzhiev, Y, Balwierz, P, Tarifeño-Saldivia, E, Cardenas, R, Wragg, J W, Suzuki, A M, Carninci, P, Peers, B, Lenhard, B, Andersen, J B & Müller, F 2020, ' Dual-initiation promoters with intertwined canonical and TCT/TOP transcription start sites diversify transcript processing ', Nature Communications, vol. 11, no. 1, 168, pp. 1-16 . https://doi.org/10.1038/s41467-019-13687-0
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nepal, C, Hadzhiev, Y, Balwierz, P, Tarifeño-Saldivia, E, Cardenas, R, Wragg, J W, Suzuki, A M, Carninci, P, Peers, B, Lenhard, B, Andersen, J B & Müller, F 2020, ' Dual-initiation promoters with intertwined canonical and TCT/TOP transcription start sites diversify transcript processing ', Nature Communications, vol. 11, no. 1, 168, pp. 1-16 . https://doi.org/10.1038/s41467-019-13687-0
Variations in transcription start site (TSS) selection reflect diversity of preinitiation complexes and can impact on post-transcriptional RNA fates. Most metazoan polymerase II-transcribed genes carry canonical initiation with pyrimidine/purine (YR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04306bc444517a8a429b282493cdb9a7
http://hdl.handle.net/10044/1/76236
http://hdl.handle.net/10044/1/76236
Autor:
Patrick Wincker, Pierre Pontarotti, Elisa de la Calle-Mustienes, Zbynek Kozmik, Malcolm Perry, José Luis Gómez-Skarmeta, Cristian Cañestro, Stéphanie Bertrand, Yamile Marquez, Èlia Benito-Gutiérrez, Juan J. Tena, Hector Escriva, Alexandra Louis, Anthony Leon, Matthew T. Weirauch, Juan Ramón Martínez-Morales, Panos N. Firbas, Peter W. H. Holland, Iryna Kozmikova, Daniel Aldea, Sandra Jiménez-Gancedo, Jordi Garcia-Fernàndez, Jean-Marc Aury, Michael Schubert, Paul Edward Duckett, Beatriz Albuixech-Crespo, Simon J. van Heeringen, Boris Lenhard, Piero Carninci, Carlos Herrera-Úbeda, Olivier Mirabeau, Demian Burguera, Lorena Buono, Tokiharu Takahashi, Rafael D. Acemel, Silvia Naranjo, Ryan Lister, Sophie Mangenot, Lucie Subirana, Ksenia Skvortsova, Jr-Kai Yu, Hugues Roest Crollius, Ildiko M. L. Somorjai, Vincent Laudet, Piotr J. Balwierz, Gabriel A. B. Marais, Ignacio Maeso, Anlong Xu, Christopher D. R. Wyatt, Shengfeng Huang, Ozren Bogdanovic, David E. K. Ferrier, Ferdinand Marlétaz, Salvatore D'Aniello, Jon Permanyer, Filipe Castro, Manuel Irimia, Ricard Albalat, Yann Le Petillon, Ensieh Farahani, Hervé Seitz
Publikováno v:
Nature
Nature, 2018, 564 (7734), pp.64-70. ⟨10.1038/s41586-018-0734-6⟩
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature, Nature Publishing Group, 2018, 564 (7734), pp.64-70. ⟨10.1038/s41586-018-0734-6⟩
Nature, 564, pp. 64-70
Digital.CSIC. Repositorio Institucional del CSIC
Dipòsit Digital de la UB
Universidad de Barcelona
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Nature, 564, 64-70
Takahashi, T & al, E 2018, ' Amphioxus functional genomics and the origins of vertebrate gene regulation ', Nature, vol. 564, pp. 64-70 . https://doi.org/10.1038/s41586-018-0734-6
Nature, 2018, 564 (7734), pp.64-70. ⟨10.1038/s41586-018-0734-6⟩
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature, Nature Publishing Group, 2018, 564 (7734), pp.64-70. ⟨10.1038/s41586-018-0734-6⟩
Nature, 564, pp. 64-70
Digital.CSIC. Repositorio Institucional del CSIC
Dipòsit Digital de la UB
Universidad de Barcelona
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Nature, 564, 64-70
Takahashi, T & al, E 2018, ' Amphioxus functional genomics and the origins of vertebrate gene regulation ', Nature, vol. 564, pp. 64-70 . https://doi.org/10.1038/s41586-018-0734-6
Vertebrates have greatly elaborated the basic chordate body plan and evolved highly distinctive genomes that have been sculpted by two whole-genome duplications. Here we sequence the genome of the Mediterranean amphioxus (Branchiostoma lanceolatum) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4beca909ac1323255e03fa32b70757ff
https://hal.science/hal-02000511
https://hal.science/hal-02000511
Autor:
Mihaela Zavolan, Erik van Nimwegen, Mikhail Pachkov, Andreas J. Gruber, Phil Arnold, Piotr J. Balwierz
As the costs of high-throughput measurement technologies continue to fall, experimental approaches in biomedicine are increasingly data intensive and the advent of big data is justifiably seen as holding the promise to transform medicine. However, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb4978d496a26a11a429ef10a475abe1
Autor:
Petra Hoffmann, Piotr J. Balwierz, Timo Lassmann, Kathrin Renner, Sayaka Nagao-Sato, David A. Hume, Yoshihide Hayashizaki, Michael Rehli, Christian Schmidl, Katrin Peter, Reinhard Andreesen, Marina Kreutz, Alistair R. R. Forrest, Harukazu Suzuki, Matthias Edinger, Piero Carninci, Masayoshi Itoh, Hideya Kawaji, Ruediger Eder
Publikováno v:
Blood. 123:e90-e99
Human blood monocytes comprise at least 3 subpopulations that differ in phenotype and function. Here, we present the first in-depth regulome analysis of human classical (CD14(++)CD16(-)), intermediate (CD14(+)CD16(+)), and nonclassical (CD14(dim)CD16
Autor:
Michael Rehli, Petra Hoffmann, Masayoshi Itoh, Hideya Kawaji, Leo Hansmann, Reinhard Andreesen, Matthias Edinger, Yoshihide Hayashizaki, Timo Lassmann, Jun Kawai, Piero Carninci, Piotr J. Balwierz, Sayaka Nagao-Sato, Christian Schmidl, Harukazu Suzuki, Alistair R. R. Forrest
Publikováno v:
Blood. 123:e68-e78
CD4(+)CD25(+)FOXP3(+) human regulatory T cells (Tregs) are essential for self-tolerance and immune homeostasis. Here, we describe the promoterome of CD4(+)CD25(high)CD45RA(+) naive and CD4(+)CD25(high)CD45RA(-) memory Tregs and their CD25(-) conventi
Autor:
Piotr J. Balwierz, Klaus Karjalainen, Erik van Nimwegen, Robert Ivanek, Antonius G. Rolink, M A Viganò, Philipp Berninger
Publikováno v:
European Journal of Immunology. 44:1181-1193
Cellular differentiation of the T-cell branch of the immune system begins with the HSC, which undergoes a series of stages characterized by progressive restriction in multipotency and acquisition of specific lineage identity At the molecular level, t