Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Piotr J Czernik"'
Autor:
Amit Chougule, Vipula Kolli, Sudipta Baroi, Nabil Ebraheim, Piotr J Czernik, Y Peng Loh, Beata Lecka‐Czernik
Publikováno v:
JBMR Plus, Vol 4, Iss 9, Pp n/a-n/a (2020)
ABSTRACT Bone and energy metabolism are integrated by common regulatory mechanisms. Carboxypeptidase E (CPE), also known as obesity susceptibility protein or neurotrophic factor‐α1, is recognized for its function in processing prohormones, includi
Externí odkaz:
https://doaj.org/article/a6d51828a21b4010acc55afefe998b2d
Autor:
Sudipta Baroi, Piotr J. Czernik, Mohd Parvez Khan, Joshua Letson, Emily Crowe, Amit Chougule, Patrick R. Griffin, Clifford J. Rosen, Beata Lecka-Czernik
Publikováno v:
Molecular Metabolism, Vol 88, Iss , Pp 102000- (2024)
Objective: The skeleton is one of the largest organs in the body, wherein metabolism is integrated with systemic energy metabolism. However, the bioenergetic programming of osteocytes, the most abundant bone cells coordinating bone metabolism, is not
Externí odkaz:
https://doaj.org/article/fd12f41dade74bab8b4e130e40b8ee7d
Autor:
Vipula Kolli, Lance A Stechschulte, Abigail R Dowling, Sima Rahman, Piotr J Czernik, Beata Lecka-Czernik
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96323 (2014)
Peroxisome proliferator activated receptor gamma (PPARγ) controls both glucose metabolism and an allocation of marrow mesenchymal stem cells (MSCs) toward osteoblast and adipocyte lineages. Its activity is determined by interaction with a ligand whi
Externí odkaz:
https://doaj.org/article/af179a5352ae4948a481dd6c3308e4fe
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51746 (2012)
Lineage allocation of the marrow mesenchymal stem cells (MSCs) to osteoblasts and adipocytes is dependent on both Wnt signaling and PPARγ2 activity. Activation of PPARγ2, an essential regulator of energy metabolism and insulin sensitivity, stimulat
Externí odkaz:
https://doaj.org/article/d5635239e2f644e28fa86b7b84b5cda8
Autor:
Amit Chougule, Sudipta Baroi, Piotr J. Czernik, Emily Crowe, Mi Ra Chang, Patrick R. Griffin, Beata Lecka-Czernik
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionThe view that bone and energy metabolism are integrated by common regulatory mechanisms is broadly accepted and supported by multiple strands of evidence. This includes the well-characterized role of the PPARγ nuclear receptor, which is
Externí odkaz:
https://doaj.org/article/1271eab095ab49fd80e70e0f7b44a2e0
Autor:
Yuan Tian, Jiyoun Yeo, Sudipta Baroi, Xi Cheng, Beng San Yeoh, Andrew D. Patterson, Matam Vijay-Kumar, Beata Lecka-Czernik, Piu Saha, Bina Joe, Saroj Chakraborty, Rachel M. Golonka, Blair Mell, Piotr J. Czernik, Ahmed A. Abokor
Publikováno v:
Physiol Genomics
Integration of microbiota in a host begins at birth and progresses during adolescence, forming a multidirectional system of physiological interactions. Here, we present an instantaneous effect of natural, bacterial gut colonization on the acceleratio
Autor:
Joseph Holoshitz, Youjie Zhang, Joshua Kim, Ritu Chakravarti, Saurabh Chattopadhyay, Krista Chun, Blair Mell, Jenna McGowan, Bina Joe, Piotr J. Czernik
Publikováno v:
Proc Natl Acad Sci U S A
Inflammatory arthritis (IA) is a common disease that affects millions of individuals worldwide. Proinflammatory events during IA pathogenesis are well studied; however, loss of protective immunity remains underexplored. Earlier, we reported that 14-3
Autor:
Xi Cheng, Piotr J. Czernik, Matam Vijay-Kumar, Ahmed A. Abokor, Saroj Chakraborty, Jiyoun Yeo, Yuan Tian, Piu Saha, Bina Joe, Sudipta Baroi, Beata Lecka-Czernik, Beng San Yeoh, Andrew D. Patterson, Rachel M. Golonka, Blair Mell
Publikováno v:
The FASEB Journal. 35
Publikováno v:
Bone
The peroxisome proliferator activated receptor gamma (PPARG) nuclear receptor regulates energy metabolism and insulin sensitivity. In this study, we present novel evidence for an essential role of PPARG in the regulation of osteocyte function, and su
Autor:
Beata Lecka-Czernik, Xi Cheng, Blair Mell, Saroj Chakraborty, Sarah Galla, Bina Joe, Ying Nie, Piotr J. Czernik
Publikováno v:
Hypertension. 76