Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Piotr Grabowski"'
Autor:
Linda Starnes, Andrew Hall, Damla Etal, Anna-Lina Cavallo, Piotr Grabowski, John Gallon, Michelle Kha, Ryan Hicks, Amy Pointon
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Creation of disease models utilizing hiPSCs in combination with CRISPR/Cas9 gene editing enable mechanistic insights into differential pharmacological responses. This allows translation of efficacy and safety findings from a healthy to a diseased sta
Externí odkaz:
https://doaj.org/article/e132b887164947bbaa01aa31e0c55474
Autor:
Georg Kustatscher, Martina Hödl, Edward Rullmann, Piotr Grabowski, Emmanuel Fiagbedzi, Anja Groth, Juri Rappsilber
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 5, Pp 1-14 (2023)
Abstract Operons are transcriptional modules that allow bacteria to adapt to environmental changes by coordinately expressing the relevant set of genes. In humans, biological pathways and their regulation are more complex. If and how human cells coor
Externí odkaz:
https://doaj.org/article/ffe5da9b79184787931496bfe0793bde
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract To provide a comprehensive analysis of small molecule genotoxic potential we have developed and validated an automated, high-content, high throughput, image-based in vitro Micronucleus (IVM) assay. This assay simultaneously assesses micronuc
Externí odkaz:
https://doaj.org/article/734ce7250fa54c68a6acc32cb4966de1
Autor:
Piotr Grabowski
Publikováno v:
Archiwa, Biblioteki i Muzea Kościelne, Vol 116 (2021)
Externí odkaz:
https://doaj.org/article/6a96ae8aedfc42f29d7f7d52c26abe35
Autor:
Piotr Grabowski
Publikováno v:
Opuscula Mathematica, Vol 38, Iss 5, Pp 651-680 (2018)
We consider a class of abstract control system of parabolic type with observation which the state, input and output spaces are Hilbert spaces. The state space operator is assumed to generate a linear exponentially stable analytic semigroup. An observ
Externí odkaz:
https://doaj.org/article/71ab0e869ba54448a6fa2b8d1dcd2d43
Publikováno v:
Molecular Systems Biology, Vol 13, Iss 8, Pp 1-14 (2017)
Abstract Genes are not randomly distributed in the genome. In humans, 10% of protein‐coding genes are transcribed from bidirectional promoters and many more are organised in larger clusters. Intriguingly, neighbouring genes are frequently coexpress
Externí odkaz:
https://doaj.org/article/e2943f44803e47ba9a9b5bfb7009ddd7
Autor:
Piotr Grabowski
Publikováno v:
Opuscula Mathematica, Vol 37, Iss 1, Pp 21-64 (2017)
Our aim is to present a solution to a general linear-quadratic (LQ) problem as well as to a Kalman-Yacubovich-Popov (KYP) problem for infinite-dimensional systems with bounded operators. The results are then applied, via the reciprocal system approac
Externí odkaz:
https://doaj.org/article/e583f481626d4788a7bfacd502e757ef
Autor:
Piotr Grabowski
Publikováno v:
Opuscula Mathematica, Vol 33, Iss 1, Pp 29-79 (2013)
The general lq-problem with infinite time horizon for well-posed infinite-dimensional systems has been investigated by George Weiss and Martin Weiss and by Olof Staffans with a complement by Kalle Mikkola and Olof Staffans. Our aim in this paper is t
Externí odkaz:
https://doaj.org/article/e4f2302a8b3e4e0db7a4c1fd92a33216
Autor:
Piotr Grabowski
Publikováno v:
Opuscula Mathematica, Vol 28, Iss 4, Pp 481-505 (2008)
This is the second part of paper [P. Grabowski, The motion planning problem and exponential stabilization of a heavy chain. Part I, to appear in International Journal of Control], where a model of a heavy chain system with a punctual load (tip mass)
Externí odkaz:
https://doaj.org/article/2acf04259bfd408eaad58f01b3c853f8
Autor:
Piotr Grabowski
Publikováno v:
Opuscula Mathematica, Vol 26, Iss 1, Pp 45-97 (2006)
The modern method of analysis of the distributed parameter systems relies on the transformation of the dynamical model to an abstract differential equation on an appropriately chosen Banach or, if possible, Hilbert space. A linear dynamical model in
Externí odkaz:
https://doaj.org/article/e915232ca8ea40dcb8bde6f807c986f9