Výsledky vyhledávání - "Piotr Dembek"

On the Application of t-Butyldimethylsilyl Group in Chemical RNA Synthesis. Part I.31P NMR Study of 2′-O-t-BDMSi Group Migration During Nucleoside 3′-OH Phosphorylation and Phosphitylation Reactions

Autor: Wieslaw Z. Antkowiak, Ryszard W. Adamiak, Zofia Gdaniec, Piotr Dembek, Jan Milecki, Slawomir Mielewczyk

Publikováno v: Nucleosides and Nucleotides. 8:463-474

31P NMR spectroscopy has been used for evaluation of 2′-O-t-BDMSi group migration during reactions of suitably protected 3′-OH ribonucleosides with P(V) and P(III) reagents used in major methodologies for oligoribonucleotide synthesis.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f2513a417ad66566ce50a9b9d5eeccd
https://doi.org/10.1080/07328318908054189

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Solid-phase synthesis of hentriacontanucleotide

Autor: Piotr Dembek, Keiichi Itakura, Kenichi Miyoshi

Publikováno v: Journal of the American Chemical Society. 103:706-708

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::06e549e116c726607462319d932dd4da
https://doi.org/10.1021/ja00393a053

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Oligonucleotide directed mutagenesis of the human beta-globin gene: a general method for producing specific point mutations in cloned DNA

Autor: Piotr Dembek, Keiichi Itakura, Merrie Jo Johnson, Monica Schold, R. Bruce Wallace

Publikováno v: Nucleic acids research. 9(15)

A nonadecanucleotide has been used both as a site specific mutagen to introduce a T leads to A transversion mutation in the human beta-globin gene cloned in pBR322 as well as a probe to screen transformed colonies for the desired mutant. The specific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::876acf43333fb96ca219112dba8bb37c
https://pubmed.ncbi.nlm.nih.gov/7279669

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