Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Piotr Hadaczek"'
Autor:
Justyna M. Przystal, Ilwoo Park, Jie Zhang, Piotr Hadaczek, Krystof Bankiewicz, Nalin Gupta, Javad Nazarian, Sabine Mueller
Publikováno v:
EJC Paediatric Oncology, Vol 2, Iss , Pp 100021- (2023)
Background: Diffuse intrinsic pontine glioma (DIPG) usually occurs in children and has poor outcomes despite treatment. Large drug screens have identified the pan-histone deacetylate inhibitor panobinostat as a promising agent, however clinical respo
Externí odkaz:
https://doaj.org/article/9c8102eee30d40d79a0cc0bd0836e77e
Autor:
Kousaku Ohno, Lluis Samaranch, Piotr Hadaczek, John R. Bringas, Philip C. Allen, Vivek Sudhakar, Diane E. Stockinger, Christopher Snieckus, Michael V. Campagna, Waldy San Sebastian, Jerusha Naidoo, Haifeng Chen, John Forsayeth, Ernesto A. Salegio, Granger G.C. Hwa, Krystof S. Bankiewicz
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 13, Iss , Pp 47-54 (2019)
Here we evaluated the utility of MRI to monitor intrathecal infusions in nonhuman primates. Adeno-associated virus (AAV) spiked with gadoteridol, a gadolinium-based MRI contrast agent, enabled real-time visualization of infusions delivered either via
Externí odkaz:
https://doaj.org/article/5a819b72674d4e9490c437bdab03d8bd
Autor:
Charles S. Cobbs, C. David James, Estefania Fiallos, Eric Singer, Lisa Matlaf, Yasuyuki Yoshida, Liliana Soroceanu, Tomoko Ozawa, Piotr Hadaczek
PDF file - 82K, 1) Protein extraction for Western blot and Western blot analysis 2) Cell culture, infection, treatment, and viability assays 3) RNA extraction and real-time PCR 4) Tissue processing and immunohistochemistry 5) Analysis and quantificat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b5d5983627155f4ca8bc7c20387493
https://doi.org/10.1158/1078-0432.22449605.v1
https://doi.org/10.1158/1078-0432.22449605.v1
Autor:
Charles S. Cobbs, C. David James, Estefania Fiallos, Eric Singer, Lisa Matlaf, Yasuyuki Yoshida, Liliana Soroceanu, Tomoko Ozawa, Piotr Hadaczek
Purpose: Cidofovir (CDV) is an U.S. Food and Drug Administration (FDA)-approved nucleoside antiviral agent used to treat severe human cytomegalovirus (HCMV) infection. Until now, no clear therapeutic effects of CDV have been reported outside of the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119f478704bccda2827371cb78b5f5ce
https://doi.org/10.1158/1078-0432.c.6521702
https://doi.org/10.1158/1078-0432.c.6521702
Autor:
Charles S. Cobbs, C. David James, Estefania Fiallos, Eric Singer, Lisa Matlaf, Yasuyuki Yoshida, Liliana Soroceanu, Tomoko Ozawa, Piotr Hadaczek
PDF file - 508K, Figure S1. CDV treatment inhibits viral gene expression in a primary GBM, endogenously infected with HMCV. Figure S2. Control to viability of U87MG after infection with HCMV. Figure S3. Treatment with Cidofovir inhibits global HCMV g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2876a4e148e23fc8e71f0bde4cc6be53
https://doi.org/10.1158/1078-0432.22449608
https://doi.org/10.1158/1078-0432.22449608
Autor:
Charles S. Cobbs, Patricia Soteropoulos, Hong Guo, Arie Perry, Lualhati Harkins, Maria-Gloria Luciani-Torres, John Ohlfest, Henrik Bengtsson, Piotr Hadaczek, Saleena Ghanny, Stacy Decker, Vladimir Bezrookove, Eric Singer, Armin Akhavan, Sabeena Khan, Lisa Matlaf, Liliana Soroceanu
IE1 Sequence Alignment in Several Primary GBM Tissues (S1); HCMV IE is enriched in the SSEA1+ fraction of primary GBM cells and co-localizes with stemness markers in situ (S2); IE siRNA Optimization (S3); HCMV transcripts are enriched in the GSC frac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bcf9f3e886475bcdba7ad5508ee3d70
https://doi.org/10.1158/0008-5472.22405820
https://doi.org/10.1158/0008-5472.22405820
Autor:
Charles S. Cobbs, Patricia Soteropoulos, Hong Guo, Arie Perry, Lualhati Harkins, Maria-Gloria Luciani-Torres, John Ohlfest, Henrik Bengtsson, Piotr Hadaczek, Saleena Ghanny, Stacy Decker, Vladimir Bezrookove, Eric Singer, Armin Akhavan, Sabeena Khan, Lisa Matlaf, Liliana Soroceanu
Detection of HCMV and cellular markers in 40 patient samples included in this study (S1); HCMV serostatus in a subset of GBM cases (S2); Histopathological and immunohistochemical characterization of spontaneous mouse gliomas (S3).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fee183ff6640744c8d89d2eef9585b5
https://doi.org/10.1158/0008-5472.22405814
https://doi.org/10.1158/0008-5472.22405814
Autor:
Charles S. Cobbs, Patricia Soteropoulos, Hong Guo, Arie Perry, Lualhati Harkins, Maria-Gloria Luciani-Torres, John Ohlfest, Henrik Bengtsson, Piotr Hadaczek, Saleena Ghanny, Stacy Decker, Vladimir Bezrookove, Eric Singer, Armin Akhavan, Sabeena Khan, Lisa Matlaf, Liliana Soroceanu
Description of additional methods and procedures used in the study. Also includes Supplementary References.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44dffc605f551f9064bccb57728c28f0
https://doi.org/10.1158/0008-5472.22405817.v1
https://doi.org/10.1158/0008-5472.22405817.v1
Autor:
Charles S. Cobbs, Patricia Soteropoulos, Hong Guo, Arie Perry, Lualhati Harkins, Maria-Gloria Luciani-Torres, John Ohlfest, Henrik Bengtsson, Piotr Hadaczek, Saleena Ghanny, Stacy Decker, Vladimir Bezrookove, Eric Singer, Armin Akhavan, Sabeena Khan, Lisa Matlaf, Liliana Soroceanu
Legend for Supplementary Figures S1-S10.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1944a4aa127a1887a4ebe97af6f9c3
https://doi.org/10.1158/0008-5472.22405823
https://doi.org/10.1158/0008-5472.22405823
Autor:
John Forsayeth, Piotr Hadaczek
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Here we advance the hypothesis that Parkinson's disease (PD) is fundamentally a failure of trophic support for specific classes of neurons, primarily catecholaminergic. Evidence from our laboratory provides a framework into which a broad array of fin
Externí odkaz:
https://doaj.org/article/328da69787ce4689b5a3f097fda82f93