Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Piotr Łyżwa"'
Publikováno v:
Molecules, Vol 29, Iss 8, p 1799 (2024)
An enzyme-promoted addition of nitromethane to the appropriate phosphorylated imine (aza-Henry reaction) intended to be used in the synthesis of the title phosphoemeriamine, a phospha-analog of emeriamine (aminocarnitine), failed due to the tautomeri
Externí odkaz:
https://doaj.org/article/709921be16e54ff39b6d26eea39caa92
Autor:
Lidia Śliwka, Katarzyna Wiktorska, Piotr Suchocki, Małgorzata Milczarek, Szymon Mielczarek, Katarzyna Lubelska, Tomasz Cierpiał, Piotr Łyżwa, Piotr Kiełbasiński, Anna Jaromin, Anna Flis, Zdzisław Chilmonczyk
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155772 (2016)
Multiple in vitro tests are widely applied to assess the anticancer activity of new compounds, including their combinations and interactions with other drugs. The MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) assay is one of the
Externí odkaz:
https://doaj.org/article/a772b63798ca4280bfa8fef6ecd6e43c
Publikováno v:
Lekarz Wojskowy. 100:66-69
Regularna aktywność fizyczna to podstawa profilaktyki chorób sercowo-naczyniowych. Pandemia koronawirusa SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) w istotny sposób wpłynęła na ograniczenie aktywności fizycznej w populacji o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::784cce7ba260f1f1975376f10cc9eb5f
https://doi.org/10.53301/lw/147102
https://doi.org/10.53301/lw/147102
Autor:
Marian Mikołajczyk, Piotr Łyżwa
Publikováno v:
Pure and Applied Chemistry. 89:357-365
This account outlines the recent results on our strategy of the diastereoselective asymmetric synthesis of aminophosphonic acids (APs) using enantiomeric sulfinimines as chirality inducing reagents. Three important topics are discussed: (a) applicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a4222fcf012c51b1e714ff5b9986209
https://doi.org/10.1515/pac-2016-1023
https://doi.org/10.1515/pac-2016-1023
Publikováno v:
Bioorganic Chemistry. 94:103377
Enzyme catalytic promiscuity is the ability of a single enzyme active site to catalyze several chemical transformations, among them those which are different from natural. We have attempted to use this feature of enzymes in the nucleophilic addition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a26d7b9da974e1cdd54a298abd430f
https://doi.org/10.1016/j.bioorg.2019.103377
https://doi.org/10.1016/j.bioorg.2019.103377
Autor:
Katarzyna Lubelska, Tomasz Cierpiał, Piotr Łyżwa, Katarzyna Wiktorska, Aleksandra Dąbrowska, Piotr Kiełbasiński, Lidia Mielczarek, Zdzisław Chilmonczyk, Hanna Kruszewska, Małgorzata Kwiatkowska, Dominika Kuran
Publikováno v:
Bioorganic Chemistry. 94:103454
A series of new sulforaphane analogs bearing various (poly)fluoroaryl substituents bonded to the sulfinyl sulfur atom in place of the original methyl group and having different number of methylene groups in the central alkyl chain were synthesized an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ed718ded3f8af286223dbb79c362ab
https://doi.org/10.1016/j.bioorg.2019.103454
https://doi.org/10.1016/j.bioorg.2019.103454
Autor:
Piotr Łyżwa, Marian Mikołajczyk
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 189:1174-1192
Aminophosphonic acids have become important in different fields of chemistry, medicine and agriculture. In this review article, we highlight a new strategy developed in the author's laboratory of asymmetric synthesis of enantiomeric aminophosphonic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59ca31486ad6af020996ea49d8d6fccc
https://doi.org/10.1080/10426507.2014.906426
https://doi.org/10.1080/10426507.2014.906426
Autor:
Piotr Łyżwa
Publikováno v:
Heteroatom Chemistry. 25:15-19
A double asymmetric induction in the synthesis of α-aminophosphonic acids is described. It involves the nucleophilic addition of anions of enantiomeric dimenthyl phosphites to both (+)-(S)- and (–)-(R)-enantiomers of N-(p-tolylsulfinyl)benzaldimin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64c7c230cf124facc30ea17a6eb2c546
https://doi.org/10.1002/hc.21130
https://doi.org/10.1002/hc.21130
Publikováno v:
European Journal of Organic Chemistry. 2013:2106-2115
We have developed new approaches to diverse enantiopure aminophosphonic acids by using enantiomeric (S)-N-(p-tolylsulfinyl)cinnamaldimine (1) as a single starting material. The synthetic strategy is based on a highly diastereoselective addition react
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c795f214a3b9a899a679c2c97f4c4b06
https://doi.org/10.1002/ejoc.201201589
https://doi.org/10.1002/ejoc.201201589
Asymmetric synthesis of conformationally constrained L-AP4 analogues using chiral sulfinyl auxiliary
Autor:
Ashraf M. Mohamed Ewas, Jerzy A. Krysiak, Piotr Łyżwa, Anna Supeł, Wanda H. Midura, Aneta Rzewnicka
Publikováno v:
Tetrahedron. 69:730-737
Constrained L-AP4 analogues, (2 S ,1′ R ,2′ S )- and (2 S ,1′ S ,2′ R )-2-(2′-phosphonocyclopropyl) glycines as well as their phenyl analogues (2 S ,1′ S ,2′ R ,3′ S )-2-(2′-phosphono-3′-phenylcyclopropyl) glycine (PPCG-1) and (2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63825aa45f75175c6d0ad448b254dc63
https://doi.org/10.1016/j.tet.2012.10.085
https://doi.org/10.1016/j.tet.2012.10.085