Zobrazeno 1 - 10
of 307
pro vyhledávání: '"Piotr, Widlak"'
Autor:
Anna Wojakowska, Lukasz Marczak, Marcin Zeman, Mykola Chekan, Ewa Zembala-Nożyńska, Krzysztof Polanski, Aleksander Strugała, Piotr Widlak, Monika Pietrowska
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundNeoadjuvant radiotherapy (neo-RT) is widely used in locally advanced rectal cancer (LARC) as a component of radical treatment. Despite the advantages of neo-RT, which typically improves outcomes in LARC patients, the lack of reliable biomar
Externí odkaz:
https://doaj.org/article/3f43c2ebf3f94730a7c3c985ab1dcc45
Autor:
Monika Pietrowska, Aneta Zebrowska, Marta Gawin, Lukasz Marczak, Priyanka Sharma, Sujan Mondal, Justyna Mika, Joanna Polańska, Soldano Ferrone, John M. Kirkwood, Piotr Widlak, Theresa L. Whiteside
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 4, Pp n/a-n/a (2021)
Abstract Molecular profiling of small extracellular vesicles (sEV) isolated from plasma of cancer patients emerges as promising strategy for biomarkers discovery. We investigated the proteomic profiles of sEV immunoselected using anti‐CSPG4 antibod
Externí odkaz:
https://doaj.org/article/85e7fb7698f447119cbb8d127eebe1e9
Autor:
Katarzyna Szołtysek, Patryk Janus, Gracjana Zając, Tomasz Stokowy, Anna Walaszczyk, Wiesława Widłak, Bartosz Wojtaś, Bartłomiej Gielniewski, Simon Cockell, Neil D. Perkins, Marek Kimmel, Piotr Widlak
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-13 (2018)
Abstract Background The cellular response to ionizing radiation involves activation of p53-dependent pathways and activation of the atypical NF-κB pathway. The crosstalk between these two transcriptional networks include (co)regulation of common gen
Externí odkaz:
https://doaj.org/article/4937e296e2514ddba4026d0e4435d9ea
Autor:
Sonja Ludwig, Lukasz Marczak, Priyanka Sharma, Agata Abramowicz, Marta Gawin, Piotr Widlak, Theresa L. Whiteside, Monika Pietrowska
Publikováno v:
OncoImmunology, Vol 8, Iss 7 (2019)
Human papillomavirus (HPV) is an etiologic factor in head and neck squamous cell carcinoma (HNSCC). HPV(+) cancers respond favorably to therapy potentially due to more robust anti-tumor immune responses. We hypothesized that tumor-derived exosomes (T
Externí odkaz:
https://doaj.org/article/e0a2c5c3f90e41438848888ffc445780
Autor:
Anna Wojakowska, Monika Pietrowska, Piotr Widlak, Dariusz Dobrowolski, Edward Wylęgała, Dorota Tarnawska
Publikováno v:
Molecules, Vol 25, Iss 12, p 2933 (2020)
The molecular etiology of keratoconus (KC), a pathological condition of the human cornea, remains unclear. The aim of this work was to perform profiling of metabolites and identification of features discriminating this pathology from the normal corne
Externí odkaz:
https://doaj.org/article/6af98b027b3841a4b05382a2164a2c96
Autor:
Karol Jelonek, Aleksandra Krzywon, Patrycja Jablonska, Ewa M. Slominska, Ryszard T. Smolenski, Joanna Polanska, Tomasz Rutkowski, Jolanta Mrochem-Kwarciak, Krzysztof Skladowski, Piotr Widlak
Publikováno v:
Metabolites, Vol 10, Iss 2, p 60 (2020)
Anticancer treatment induces systemic molecular changes that could be detected at the level of biofluids. Understanding how human metabolism is influenced by these treatments is crucial to predict the individual response and adjust personalized thera
Externí odkaz:
https://doaj.org/article/86b3b163e9a141e1b7590898601ea566
Autor:
Agata Abramowicz, Lukasz Marczak, Anna Wojakowska, Szczepan Zapotoczny, Theresa L Whiteside, Piotr Widlak, Monika Pietrowska
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205496 (2018)
Exosomes, the smallest subset of extracellular vesicles (EVs), have recently attracted much attention in the scientific community. Their involvement in intercellular communication and molecular reprogramming of different cell types created a demand f
Externí odkaz:
https://doaj.org/article/8a5e33bd311744ce8fd0ca96570fc8d4
Autor:
Monika Pietrowska, Karol Jelonek, Joanna Polanska, Anna Wojakowska, Lukasz Marczak, Ewa Chawinska, Aleksanda Chmura, Wojciech Majewski, Leszek Miszczyk, Piotr Widlak
Publikováno v:
Proteomes, Vol 3, Iss 3, Pp 117-131 (2015)
Partial body irradiation during cancer radiotherapy (RT) induces a response of irradiated tissues that could be observed at the level of serum proteome. Here we aimed to characterize the response to RT in group of patients treated because of prostate
Externí odkaz:
https://doaj.org/article/3fe8ee1ad0544a83808326fed678888c
Publikováno v:
Expert Review of Proteomics. 17:335-340
Central and Eastern European Proteomic Conference (CEEPC) provides a platform for researchers to discuss multi-disciplinary integrated approaches to address a range of challenges from present day v...
Autor:
Anna Paszek, Joanna Polanska, Patryk Janus, Natalia Vydra, Wieslawa Widlak, Joanna Korfanty, Karolina Dudek, Marek Chadalski, Agnieszka Toma-Jonik, Piotr Widlak, Katarzyna Mrowiec, Marek Rusin
Publikováno v:
Cell Death and Differentiation
Heat shock can induce either cytoprotective mechanisms or cell death. We found that in certain human and mouse cells, including spermatocytes, activated heat shock factor 1 (HSF1) binds to sequences located in the intron(s) of the PMAIP1 (NOXA) gene