Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Piotr, Kraj"'
Autor:
Piotr Kraj
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The transforming growth factor-β (TGF-β) family includes cytokines controlling cell behavior, differentiation and homeostasis of various tissues including components of the immune system. Despite well recognized importance of TGF-β in controlling
Externí odkaz:
https://doaj.org/article/948bbeaf0dd947db9d59073d5df80967
Autor:
Anna Cebula, Michal Kuczma, Edyta Szurek, Maciej Pietrzak, Natasha Savage, Wessam R. Elhefnawy, Grzegorz Rempala, Piotr Kraj, Leszek Ignatowicz
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Autoreactive T cells are normally eliminated during their maturation in the thymus, but an unknown number of autoreactive CD4+ T cells escape to the periphery. Here the authors show, by comparing the T cell receptors of mice sufficient or deficient i
Externí odkaz:
https://doaj.org/article/f0ecadad87d6496c8f838eae6f2b9404
Autor:
Lauren M. Browning, Caroline Miller, Michal Kuczma, Maciej Pietrzak, Yu Jing, Grzegorz Rempala, Pawel Muranski, Leszek Ignatowicz, Piotr Kraj
Publikováno v:
Cell Reports, Vol 33, Iss 1, Pp 108219- (2020)
Summary: Bone morphogenic proteins (BMPs) are members of the transforming growth factor β (TGF-β) cytokine family promoting differentiation, homeostasis, and self-renewal of multiple tissues. We show that signaling through the bone morphogenic prot
Externí odkaz:
https://doaj.org/article/667fc846294b4f0a8093f179d49af5a6
Autor:
Lin Ran, Qilin Yu, Shu Zhang, Fei Xiong, Jia Cheng, Ping Yang, Jun-Fa Xu, Hao Nie, Qin Zhong, Xueli Yang, Fei Yang, Quan Gong, Michal Kuczma, Piotr Kraj, Weikuan Gu, Bo-Xu Ren, Cong-Yi Wang
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 7, Pp 691-700 (2015)
Acute schistosomiasis is characterized by pro-inflammatory responses against tissue- or organ-trapped parasite eggs along with granuloma formation. Here, we describe studies in Cx3cr1−/− mice and demonstrate the role of Cx3cr1 in the pathoetiolog
Externí odkaz:
https://doaj.org/article/abf6e2fd64e24715af5d37dd12444f1e
Autor:
Piotr Kraj, Vu L. Ngo, Maciej Pietrzak, Michal Kuczma, Timothy L. Denning, Leszek Ignatowicz, Edyta Szurek, Anna Cebula
Publikováno v:
Mucosal Immunology. 14:443-454
The physiological role of T cell anergy induction as a key mechanism supporting self-tolerance remains undefined, and natural antigens that induce anergy are largely unknown. In this report, we used TCR sequencing to show that the recruitment of CD4+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d88a47f1d6ca4b21cfe8ba56d395f772
https://doi.org/10.1038/s41385-020-00349-4
https://doi.org/10.1038/s41385-020-00349-4
Autor:
Edyta Szurek, Michal Kuczma, Maciej Pietrzak, Piotr Kraj, Wessam Elhefnawy, Leszek Ignatowicz, Natasha M. Savage, Grzegorz A. Rempala, Anna Cebula
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Thymic central tolerance eliminates most immature T cells with autoreactive T cell receptors (TCR) that recognize self MHC/peptide complexes. Regardless, an unknown number of autoreactive CD4+Foxp3− T cells escape negative selection and in the peri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9d7d02918154ee2073d14bed22a79a
http://link.springer.com/article/10.1038/s41467-019-12820-3
http://link.springer.com/article/10.1038/s41467-019-12820-3
Autor:
Piotr Kraj
Publikováno v:
Current Treatment Options in Oncology. 22
Malignant melanoma is a deadly form of skin cancer caused by neoplastic transformation of melanocytic cells. Despite recent progress in melanoma therapy, by inhibition of activated oncogenes or immunotherapy, survival rate for metastatic melanoma pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c13d83f666d72626bdfe5e1e27d1e8b9
https://doi.org/10.1007/s11864-021-00849-w
https://doi.org/10.1007/s11864-021-00849-w
Autor:
Girish Neelakanta, S Dutta, Jessa Faye Arca, John F. Anderson, Michael J. Celestine, Alvin A. Holder, Alexis Huddleston, Michel Ledizet, Hameeda Sultana, Piotr Kraj, Colin Simms, Amlan Mitra, Loree C. Heller, Supreet Khanal
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1862:40-50
Trace elements such as copper and cobalt have been associated with virus-host interactions. However, studies to show the effect of conjugation of copper(II) or cobalt(III) metal centers to thiosemicarbazone ligand(s) derived from either food additive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dfd3cf7427a58ae68ae37943185a18d
https://doi.org/10.1016/j.bbagen.2017.10.004
https://doi.org/10.1016/j.bbagen.2017.10.004
Autor:
Michal Kuczma, Magdalena Kopij, Iwona Pawlikowska, Cong-Yi Wang, Grzegorz A Rempala, Piotr Kraj
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13623 (2010)
The presence of Foxp3(+) regulatory CD4(+) T cells in tumor lesions is considered one of the major causes of ineffective immune response in cancer. It is not clear whether intratumoral T(reg) cells represent T(reg) cells pre-existing in healthy mice,
Externí odkaz:
https://doaj.org/article/1fd0afa053e04601b6678dc836548aa4
Autor:
Lauren M, Browning, Caroline, Miller, Michal, Kuczma, Maciej, Pietrzak, Yu, Jing, Grzegorz, Rempala, Pawel, Muranski, Leszek, Ignatowicz, Piotr, Kraj
Publikováno v:
Cell Rep
Bone morphogenic proteins (BMPs) are members of the transforming growth factor β (TGF-β) cytokine family promoting differentiation, homeostasis, and self-renewal of multiple tissues. We show that signaling through the bone morphogenic protein recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f783c69f62c09443b7fa1b079204c080
https://pubmed.ncbi.nlm.nih.gov/33027660
https://pubmed.ncbi.nlm.nih.gov/33027660