Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Piotr, Gruca"'
Autor:
Paola Brivio, Maria Teresa Gallo, Matteo Audano, Gaia Galassi, Piotr Gruca, Magdalena Lason, Ewa Litwa, Fabio Fumagalli, Mariusz Papp, Nico Mitro, Francesca Calabrese
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract The concept of resilience has changed over time and nowadays it refers to the positive adaptation to life adversities, rather than to the absence of a pathological response normally occurring in susceptible people. Based on our previous data
Externí odkaz:
https://doaj.org/article/04224e724cf2424d8442174eb9722aaa
Autor:
Ewa Litwa, Piotr Gruca, Magdalena Łasoń, Bartosz Bobula, Aleksandra Bartosz-Nowakowska, Mariusz Papp
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S600- (2023)
Externí odkaz:
https://doaj.org/article/59f23a0730dc45b79b332a15f7a46bd9
Autor:
Paola Brivio, Matteo Audano, Maria Teresa Gallo, Piotr Gruca, Magdalena Lason, Ewa Litwa, Fabio Fumagalli, Mariusz Papp, Nico Mitro, Francesca Calabrese
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Stress is the foremost environmental factor involved in the pathophysiology of major depressive disorder (MDD). However, individual differences among people are critical as some people exhibit vulnerability while other are resilient to repea
Externí odkaz:
https://doaj.org/article/ae74e88bcbcc434280f0f513452def08
Autor:
Paola Brivio, Erica Buoso, Mirco Masi, Maria Teresa Gallo, Piotr Gruca, Magdalena Lason, Ewa Litwa, Mariusz Papp, Fabio Fumagalli, Marco Racchi, Emanuela Corsini, Francesca Calabrese
Publikováno v:
Neurobiology of Stress, Vol 15, Iss , Pp 100372- (2021)
Several intracellular pathways that contribute to the adaptation or maladaptation to environmental challenges mediate the vulnerability and resilience to chronic stress. The activity of the hypothalamic-pituitary-adrenal (HPA) axis is fundamental for
Externí odkaz:
https://doaj.org/article/f260d5ef9cb6403e9a24d27ce06ad8a4
Autor:
Paulina Cieślik, Monika Woźniak, Katarzyna Kaczorowska, Piotr Brański, Grzegorz Burnat, Agnieszka Chocyk, Bartosz Bobula, Piotr Gruca, Ewa Litwa, Agnieszka Pałucha-Poniewiera, Agnieszka Wąsik, Andrzej Pilc, Joanna Wierońska
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
The data concerning antipsychotic-like activity of negative allosteric modulators (NAMs)/antagonists of mGlu7 receptors are limited. The only available ligands for this receptor are MMPIP and ADX71743. In the present studies, we used stable cell line
Externí odkaz:
https://doaj.org/article/66f5e82cf27e42e083abcb496054ea7a
Autor:
Paola Brivio, Maria Teresa Gallo, Piotr Gruca, Magdalena Lason, Ewa Litwa, Fabio Fumagalli, Mariusz Papp, Francesca Calabrese
Publikováno v:
European Archives of Psychiatry and Clinical Neuroscience.
Stress is a major precipitating factor for psychiatric disorders and its effects may depend on its duration and intensity. Of note, there are differences in individual susceptibility to stress, with some subjects displaying vulnerability and others s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b0cd17d8938830d0b63ef9dfafc8d1
https://doi.org/10.1007/s00406-022-01470-0
https://doi.org/10.1007/s00406-022-01470-0
Autor:
Paola Brivio, Maria Teresa Gallo, Piotr Gruca, Magdalena Lason, Ewa Litwa, Fabio Fumagalli, Mariusz Papp, Francesca Calabrese
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7321
Despite several antidepressant treatments being available in clinics, they are not effective in all patients. In recent years, N-acetylcysteine (NAC) has been explored as adjunctive therapy for many psychiatric disorders, including depression, for it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48745bdee502dbf23f0be8ecaa4ca861
https://doi.org/10.3390/ijms24087321
https://doi.org/10.3390/ijms24087321
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 123:110715
Our earlier study demonstrated that repeated optogenetic stimulation of afferents from ventral hippocampus (vHIP) to the prelimbic region of medial prefrontal cortex (mPFC) overcame resistance to antidepressant treatment in Wistar-Kyoto (WKY) rats. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58675871af1de684bc267a4bb07834d4
https://doi.org/10.1016/j.pnpbp.2023.110715
https://doi.org/10.1016/j.pnpbp.2023.110715
Publikováno v:
Journal of Psychopharmacology (Oxford, England)
Background: The chronic mild stress (CMS) procedure is a widely used animal model of depression, and its application in Wistar–Kyoto (WKY) rats has been validated as a model of antidepressant-refractory depression. While not responding to chronic t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d68e355d9cef23fdce4afc8a9b176b0
https://doi.org/10.1177/0269881120967857
https://doi.org/10.1177/0269881120967857
Autor:
Renata Pukło, Magdalena Łasoń, Władysława A. Daniel, Mariusz Papp, Ewa Bromek, Anna Haduch, Marta Rysz, Monika Niemczyk, Piotr Gruca
Publikováno v:
Pharmacological Reports
Background The aim of our research was to determine the effects of chronic treatment with the atypical antidepressant agomelatine on the expression and activity of liver cytochrome P450 (CYP) in the chronic mild stress (CMS) model of depression, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2216ae0df0c5f2929d8d75e05337bb41
https://doi.org/10.1007/s43440-020-00151-w
https://doi.org/10.1007/s43440-020-00151-w