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Autor:
Guido Cavaletti, Jason A. Sprowl, Alix F. Leblanc, Kevin M. Huang, Alice A. Gibson, Alex Sparreboom, Vamsi Chodisetty, Paola Alberti, Alessia Chiorazzi, Peter de Bruijn, Olivia Costa, Shuiying Hu, Tatiana Florea, W. David Arnold, Maryam B. Lustberg, Ron H.J. Mathijssen, Marissa S. Pioso, Mingqing Chen, Kristen W. Hong, Raquel E. Reinbolt, Lara E. Sucheston-Campbell
Publikováno v:
Journal of Clinical Investigation, 128(2), 816-825. The American Society for Clinical Investigation
Paclitaxel is among the most widely used anticancer drugs and is known to cause a dose-limiting peripheral neurotoxicity, the initiating mechanisms of which remain unknown. Here, we identified the murine solute carrier organic anion-transporting poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::338fcf830505445c49dc138ac42c6565
https://doi.org/10.1172/jci96160
https://doi.org/10.1172/jci96160
Autor:
Fernandez EG; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA., Mai WX; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA., Song K; Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA., Bayley NA; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA., Kim J; Department of Biostatistics, Jonathan and Karin Fielding School of Public Health, Los Angeles, California, USA., Zhu H; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA., Pioso M; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA., Young P; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA., Andrasz CL; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA.; Department of Human Genetics, University of California, Los Angeles, CA, 90095-7088, USA., Cadet D; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA., Liau LM; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Li G; Department of Biostatistics, Jonathan and Karin Fielding School of Public Health, Los Angeles, California, USA., Yong WH; Department of Pathology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Rodriguez FJ; Department of Pathology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Dixon SJ; Department of Biology, Stanford University, Stanford, CA, 94305, USA., Souers AJ; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA., Li JJ; Department of Biostatistics, Jonathan and Karin Fielding School of Public Health, Los Angeles, California, USA.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Human Genetics, University of California, Los Angeles, CA, 90095-7088, USA.; Department of Computational Medicine, University of California, Los Angeles, CA, 90095-1766, USA.; Department of Statistics and Data Science, University of California, Los Angeles, CA, 90095-1554, USA., Graeber TG; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA, USA.; UCLA Metabolomics Center, University of California Los Angeles, Los Angeles, CA, 90095, USA.; Crump Institute for Molecular Imaging, University of California Los Angeles, Los Angeles, CA, 90095, USA., Cloughesy TF; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Nathanson DA; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA. dnathanson@mednet.ucla.edu.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA, USA. dnathanson@mednet.ucla.edu.
Publikováno v:
Nature communications [Nat Commun] 2024 Nov 21; Vol. 15 (1), pp. 10089. Date of Electronic Publication: 2024 Nov 21.