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pro vyhledávání: '"Piomponi, Valerio"'
N6-methyladenosine (m6A) is a prevalent RNA post-transcriptional modification that plays crucial roles in RNA stability, structural dynamics, and interactions with proteins. The YT521-B (YTH) family of proteins, which are notable m6A readers, functio
Externí odkaz:
http://arxiv.org/abs/2404.14821
Publikováno v:
In: Barciszewski, J. (eds) RNA Structure and Function. RNA Technologies, vol 14 (2023). Springer, Cham
Post-transcriptional modifications are crucial for RNA function, with roles ranging from the stabilization of functional RNA structures to modulation of RNA--protein interactions. Additionally, artificially modified RNAs have been suggested as optima
Externí odkaz:
http://arxiv.org/abs/2211.13657
Performing alchemical transformations, in which one molecular system is nonphysically changed to another system, is a popular approach adopted in performing free energy calculations associated with various biophysical processes, such as protein-ligan
Externí odkaz:
http://arxiv.org/abs/2206.01329
Publikováno v:
ACS Cent. Sci. 2022, 8, 8, 1218-1228
Post-transcriptional modifications are crucial for RNA function and can affect its structure and dynamics. Force-field based classical molecular dynamics simulations are a fundamental tool to characterize biomolecular dynamics and their application t
Externí odkaz:
http://arxiv.org/abs/2203.14886
Akademický článek
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Publikováno v:
ACS Central Science; 8/24/2022, Vol. 8 Issue 8, p1218-1228, 11p
Akademický článek
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Autor:
Piomponi V; Scuola Internazionale Superiore di Studi Avanzati, SISSA, Via Bonomea 265, Trieste 34136, Italy.; Area Science Park, località Padriciano, 99, Trieste 34149, Italy., Krepl M; Institute of Biophysics of the Czech Academy of Sciences, Kralovopolská 135, Brno 612 00, Czech Republic., Sponer J; Institute of Biophysics of the Czech Academy of Sciences, Kralovopolská 135, Brno 612 00, Czech Republic., Bussi G; Scuola Internazionale Superiore di Studi Avanzati, SISSA, Via Bonomea 265, Trieste 34136, Italy.
Publikováno v:
The journal of physical chemistry. B [J Phys Chem B] 2024 Sep 19; Vol. 128 (37), pp. 8896-8907. Date of Electronic Publication: 2024 Sep 06.