Palmitic acid control of ciliogenesis modulates insulin signaling in hypothalamic neurons through an autophagy-dependent mechanism.

Autor: Ávalos Y; Departamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile., Hernández-Cáceres MP; Laboratory of Autophagy and Metabolism, Department of Physiology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.; Cellular and Molecular Biology Laboratory, Institute in Dentistry Sciences, Dentistry Faculty, Universidad de Chile, Santiago, Chile., Lagos P; Laboratory of Autophagy and Metabolism, Department of Physiology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile., Pinto-Nuñez D; Laboratory of Autophagy and Metabolism, Department of Physiology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile., Rivera P; Laboratory of Autophagy and Metabolism, Department of Physiology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile., Burgos P; Laboratory of Autophagy and Metabolism, Department of Physiology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile., Díaz-Castro F; Laboratory of Autophagy and Metabolism, Department of Physiology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile., Joy-Immediato M; Laboratory for Molecular Mechanics of Cell Adhesion, Pontificia Universidad Católica de Chile, Santiago, Chile., Venegas-Zamora L; Advanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences and Faculty of Medicine, Universidad de Chile, Santiago, Chile., Lopez-Gallardo E; Advanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences and Faculty of Medicine, Universidad de Chile, Santiago, Chile., Kretschmar C; Cellular and Molecular Biology Laboratory, Institute in Dentistry Sciences, Dentistry Faculty, Universidad de Chile, Santiago, Chile., Batista-Gonzalez A; Cellular and Molecular Biology Laboratory, Institute in Dentistry Sciences, Dentistry Faculty, Universidad de Chile, Santiago, Chile., Cifuentes-Araneda F; Laboratory of Autophagy and Metabolism, Department of Physiology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile., Toledo-Valenzuela L; Laboratory of Autophagy and Metabolism, Department of Physiology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile., Rodriguez-Peña M; Cellular and Molecular Biology Laboratory, Institute in Dentistry Sciences, Dentistry Faculty, Universidad de Chile, Santiago, Chile., Espinoza-Caicedo J; Laboratory of Autophagy and Metabolism, Department of Physiology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile., Perez-Leighton C; Department of Physiology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile., Bertocchi C; Laboratory for Molecular Mechanics of Cell Adhesion, Pontificia Universidad Católica de Chile, Santiago, Chile., Cerda M; Integrative Biology Program, Institute of Biomedical Sciences, Facultad de Medicina, Universidad de Chile, Santiago, Chile.; Center for Medical Informatics and Telemedicine, Facultad de Medicina, Universidad de Chile, Santiago, Chile.; Biomedical Neuroscience Institute, Santiago, Chile., Troncoso R; Advanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences and Faculty of Medicine, Universidad de Chile, Santiago, Chile.; Instituto de Nutrición y Tecnología de los Alimentos (INTA), Universidad de Chile, Santiago, Chile.; Autophagy Research Center, Santiago, Chile., Parra V; Advanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences and Faculty of Medicine, Universidad de Chile, Santiago, Chile.; Autophagy Research Center, Santiago, Chile.; Network for the Study of High-Lethality Cardiopulmonary Diseases (REECPAL), Universidad de Chile, Santiago, Chile., Budini M; Autophagy Research Center, Santiago, Chile.; Laboratory of Molecular and Cellular Pathology, Institute in Dentistry Sciences, Dentistry Faculty, Universidad de Chile, Santiago, Chile., Burgos PV; Autophagy Research Center, Santiago, Chile.; Centro de Biología Celular y Biomedicina (CEBICEM), Facultad de Medicina y Ciencia, Universidad San Sebastián, Santiago, Chile.; Centro de Envejecimiento y Regeneración (CARE-UC), Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile., Criollo A; Cellular and Molecular Biology Laboratory, Institute in Dentistry Sciences, Dentistry Faculty, Universidad de Chile, Santiago, Chile. alcriollo@u.uchile.cl.; Advanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences and Faculty of Medicine, Universidad de Chile, Santiago, Chile. alcriollo@u.uchile.cl.; Autophagy Research Center, Santiago, Chile. alcriollo@u.uchile.cl., Morselli E; Laboratory of Autophagy and Metabolism, Department of Physiology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile. eugenia.morselli@uss.cl.; Autophagy Research Center, Santiago, Chile. eugenia.morselli@uss.cl.; Department of Basic Sciences, Faculty of Medicine and Sciences, Universidad San Sebastián, Santiago, Chile. eugenia.morselli@uss.cl.

Publikováno v: Cell death & disease [Cell Death Dis] 2022 Jul 28; Vol. 13 (7), pp. 659. Date of Electronic Publication: 2022 Jul 28.

The autophagy-lysosome pathway: a potential target in the chemical and gene therapeutic strategies for Parkinson's disease.

Autor: Jiao F; School of Mental Health, Jining Medical University, Jining, Shandong Province, China.; Shandong Collaborative Innovation Center for Diagnosis, Treatment and Behavioral Interventions of Mental Disorders, Institute of Mental Health, Jining Medical University, Jining, Shandong Province, China., Meng L; School of Mental Health, Jining Medical University, Jining, Shandong Province, China., Du K; School of Mental Health, Jining Medical University, Jining, Shandong Province, China., Li X; School of Mental Health, Jining Medical University, Jining, Shandong Province, China.; Shandong Collaborative Innovation Center for Diagnosis, Treatment and Behavioral Interventions of Mental Disorders, Institute of Mental Health, Jining Medical University, Jining, Shandong Province, China.

Publikováno v: Neural regeneration research [Neural Regen Res] 2025 Jan 01; Vol. 20 (1), pp. 139-158. Date of Electronic Publication: 2024 Jan 31.

Regulation of genes involved in the metabolic adaptation of murine microglial cells in response to elevated HIF-1α mediated activation.

Autor: Florance I; Center for Nanobiotechnology, Vellore Institute of Technology, Vellore, Tamil Nadu, 632014, India., Ramasubbu S; Center for Nanobiotechnology, Vellore Institute of Technology, Vellore, Tamil Nadu, 632014, India. rseenivasan@vit.ac.in.

Publikováno v: Immunogenetics [Immunogenetics] 2024 Apr; Vol. 76 (2), pp. 93-108. Date of Electronic Publication: 2024 Feb 08.

Cilia: From Mechanisms to Disease–Part B

Autor: Jose Manuel Bravo-San Pedro, Lorenzo Galluzzi

Cilia: From Mechanisms to Disease Part B, Volume 176 of the Methods in Cell Biology series, presents interesting chapters on topics such as The challenge of dissecting gene function in model organisms: tools to characterize genetic mutants and assess