Nitazoxanide In Vitro Efficacy Against SARS CoV-2 and In Vivo Superiority to Placebo to Treat Moderate COVID-19 – A Phase 2 Randomized Double-Blind Clinical Trial

Autor: Pinto Rn, Juliana Galinskas, Janini Lmr, Acioly Lacerda, Belley Nc, Sergio Cimerman, Karcher D, Florentino Cardoso, Paulo Tierno, Danilo Rocha Dias, Hunter, Alda Maria Da-Cruz, Marcella Vassao, N Mantovani, Fonseca Fmp, Ricardo Sobhie Diaz, Vinicius Fontanesi Blum, Juliana Terzi Maricato, Santos-Oliveira, Alexandre Soeiro

Publikováno v: SSRN Electronic Journal.

Background: The absence of specific antivirals to treat COVID-19 leads to the repositioning of candidates’ drugs. Nitazoxanide (NTZ) has a broad antiviral effect. Methods: The in vitro effect of NTZ in VERO E6 cells was evaluated, followed by a ran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::810a6aa86f5da254537a8ee5b7ffc367
https://doi.org/10.2139/ssrn.3763773

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Performance of a new implant system and drilling protocol-A minipig intraoral dental implant model study.

Autor: Musskopf ML; Laboratory for Applied Periodontal & Craniofacial Research, Division of Comprehensive Oral Health - Periodontology, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Finger Stadler A; Laboratory for Applied Periodontal & Craniofacial Research, Division of Comprehensive Oral Health - Periodontology, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Fiorini T; Department of Conservative Dentistry - Periodontology, Faculty of Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, Brazil., Ramos UD; Private Practice, Vitoria, Brazil., de Sousa Rabelo M; Private Practice, Sao Paulo, Brazil., de Castro Pinto RN; Private Practice, Sao Paulo, Brazil.; FUNDECTO, University of Sao Paulo, Sao Paulo, Brazil., Susin C; Laboratory for Applied Periodontal & Craniofacial Research, Division of Comprehensive Oral Health - Periodontology, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Publikováno v: Clinical oral implants research [Clin Oral Implants Res] 2024 Jan; Vol. 35 (1), pp. 40-51. Date of Electronic Publication: 2023 Oct 19.

Objective assessment of stored blood quality by deep learning.

Autor: Doan M; Imaging Platform, Broad Institute of MIT and Harvard, Cambridge, MA 02142., Sebastian JA; Department of Physics, Ryerson University, Toronto, ON M5B 2K3, Canada.; Institute of Biomedical Engineering, Science and Technology, a partnership between Ryerson University and St. Michael's Hospital, Toronto, ON M5B 1T8, Canada.; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON M5B 1W8, Canada., Caicedo JC; Imaging Platform, Broad Institute of MIT and Harvard, Cambridge, MA 02142., Siegert S; Flow Cytometry Facility, Department of Formation and Research, University of Lausanne, 1015 Lausanne, Switzerland., Roch A; Department of Pathology and Immunology, University of Geneva, 1205 Geneva, Switzerland., Turner TR; Centre for Innovation, Canadian Blood Services, Edmonton, AB T6G 2R8, Canada., Mykhailova O; Centre for Innovation, Canadian Blood Services, Edmonton, AB T6G 2R8, Canada., Pinto RN; Department of Physics, Ryerson University, Toronto, ON M5B 2K3, Canada.; Institute of Biomedical Engineering, Science and Technology, a partnership between Ryerson University and St. Michael's Hospital, Toronto, ON M5B 1T8, Canada.; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON M5B 1W8, Canada., McQuin C; Imaging Platform, Broad Institute of MIT and Harvard, Cambridge, MA 02142., Goodman A; Imaging Platform, Broad Institute of MIT and Harvard, Cambridge, MA 02142., Parsons MJ; Flow Cytometry Core Facilities, Lunenfeld-Tanenbaum Research Institute, Toronto, ON M5G 1X5, Canada., Wolkenhauer O; Department of Systems Biology & Bioinformatics, University of Rostock, 18051 Rostock, Germany., Hennig H; Department of Systems Biology & Bioinformatics, University of Rostock, 18051 Rostock, Germany., Singh S; Imaging Platform, Broad Institute of MIT and Harvard, Cambridge, MA 02142., Wilson A; Flow Cytometry Facility, Department of Formation and Research, University of Lausanne, 1015 Lausanne, Switzerland.; Department of Oncology, University of Lausanne, CH-1066 Epalinges, Switzerland., Acker JP; Centre for Innovation, Canadian Blood Services, Edmonton, AB T6G 2R8, Canada.; Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB T6G 2R3, Canada., Rees P; Imaging Platform, Broad Institute of MIT and Harvard, Cambridge, MA 02142.; College of Engineering, Swansea University, SA2 APP Swansea, United Kingdom., Kolios MC; Department of Physics, Ryerson University, Toronto, ON M5B 2K3, Canada; mkolios@ryerson.ca anne@broadinstitute.org.; Institute of Biomedical Engineering, Science and Technology, a partnership between Ryerson University and St. Michael's Hospital, Toronto, ON M5B 1T8, Canada.; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON M5B 1W8, Canada., Carpenter AE; Imaging Platform, Broad Institute of MIT and Harvard, Cambridge, MA 02142; mkolios@ryerson.ca anne@broadinstitute.org.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Sep 01; Vol. 117 (35), pp. 21381-21390. Date of Electronic Publication: 2020 Aug 24.

Label-Free Analysis of Red Blood Cell Storage Lesions Using Imaging Flow Cytometry.

Autor: Pinto RN; Institute of Biomedical Engineering Science and Technology (iBEST), Toronto, Ontario, M5B 1T8, Canada.; Department of Physics, Ryerson University, Toronto, Ontario, M5B 2K3, Canada., Sebastian JA; Institute of Biomedical Engineering Science and Technology (iBEST), Toronto, Ontario, M5B 1T8, Canada.; Department of Electrical, Computer, and Biomedical Engineering, Ryerson University, Toronto, Ontario, M5B 2K3, Canada., Parsons MJ; Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, M5G 1X5, Canada., Chang TC; MilliporeSigma, a business of Merck KGaA, Seattle, Washington, 98119., Turner TR; Centre for Innovation, Canadian Blood Services, Edmonton, Alberta, T6G 2R8, Canada., Acker JP; Centre for Innovation, Canadian Blood Services, Edmonton, Alberta, T6G 2R8, Canada.; Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, T6G 2R8, Canada., Kolios MC; Institute of Biomedical Engineering Science and Technology (iBEST), Toronto, Ontario, M5B 1T8, Canada.; Department of Physics, Ryerson University, Toronto, Ontario, M5B 2K3, Canada.

Publikováno v: Cytometry. Part A : the journal of the International Society for Analytical Cytology [Cytometry A] 2019 Sep; Vol. 95 (9), pp. 976-984. Date of Electronic Publication: 2019 Jul 11.