Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Pino J. Poddighe"'
Autor:
Daan A.R. Castelijn, Gerrit Sijm, Bianca Venniker-Punt, Pino J. Poddighe, Marielle J. Wondergem
Publikováno v:
Case Reports in Oncology, Vol 16, Iss 1, Pp 1443-1450 (2023)
Introduction: Acute promyelocytic leukemia (APL) is characterized by the PML::RARa gene fusion and treatment consists of all-trans retinoic acid (ATRA). Rarely, genetic APL variants have been described which are insensitive to ATRA treatment and are
Externí odkaz:
https://doaj.org/article/3767674746294f78937366942e55047d
Autor:
Nathalie van Leeuwen-Kerkhoff, Theresia M. Westers, Pino J. Poddighe, Giovanni A.M. Povoleri, Jessica A. Timms, Shahram Kordasti, Tanja D. de Gruijl, Arjan A. van de Loosdrecht
Publikováno v:
Haematologica, Vol 107, Iss 3 (2021)
In myelodysplastic syndromes (MDS) the immune system is involved in pathogenesis as well as in disease progression. Dendritic cells (DC) are key players of the immune system by serving as regulators of immune responses. Their function has been scarce
Externí odkaz:
https://doaj.org/article/26f1528540ce4db4a14df7d35edc7962
Autor:
Nathalie van Leeuwen-Kerkhoff, Theresia M. Westers, Pino J. Poddighe, Tanja D. de Gruijl, Shahram Kordasti, Arjan A. van de Loosdrecht
Publikováno v:
Haematologica, Vol 105, Iss 4 (2020)
The bone marrow of patients with low-risk myelodysplastic syndromes (MDS) is often an inflammatory environment and associated with an active cellular immune response. An active immune response generally contributes to antitumor responses and may prev
Externí odkaz:
https://doaj.org/article/ce1bc9bd25e44a2e8185f575615a02f2
Autor:
Sonja Zweegman, Claudia A.M. Stege, Einar Haukas, Fredrik H. Schjesvold, Mark-David Levin, Anders Waage, Rineke B.L. Leys, Saskia K. Klein, Damian Szatkowski, Per Axelsson, Trung Hieu Do, Dorota Knut-Bojanowska, Ellen van der Spek, Asta Svirskaite, Anja Klostergaard, Morten Salomo, Celine Blimark, Paula F. Ypma, Ulf-Henrik Mellqvist, Pino J. Poddighe, Marian Stevens-Kroef, Niels W.C.J. van de Donk, Pieter Sonneveld, Markus Hansson, Bronno van der Holt, Niels Abildgaard
Publikováno v:
Haematologica, Vol 105, Iss 12 (2020)
Externí odkaz:
https://doaj.org/article/ae2dab95ebb94eb98d88468acc0873bc
Autor:
Iris E Glykofridis, Jaco C Knol, Jesper A Balk, Denise Westland, Thang V Pham, Sander R Piersma, Sinéad M Lougheed, Sepide Derakhshan, Puck Veen, Martin A Rooimans, Saskia E van Mil, Franziska Böttger, Pino J Poddighe, Irma van de Beek, Jarno Drost, Fried JT Zwartkruis, Renee X de Menezes, Hanne EJ Meijers-Heijboer, Arjan C Houweling, Connie R Jimenez, Rob MF Wolthuis
Publikováno v:
eLife, Vol 10 (2021)
Germline mutations in the Folliculin (FLCN) tumor suppressor gene cause Birt–Hogg–Dubé (BHD) syndrome, a rare autosomal dominant disorder predisposing carriers to kidney tumors. FLCN is a conserved, essential gene linked to diverse cellular proc
Externí odkaz:
https://doaj.org/article/afeb46d1c35540eaa522d75e244c66bd
Autor:
Niels W.C.J. van de Donk, Tuna Mutis, A. Kate Sasser, Henk M. Lokhorst, Torben Plesner, Christopher Chiu, Richard W.J. Groen, Pino J. Poddighe, René J.P. Musters, Johan van Meerloo, Sonja Zweegman, Marloes E.C. Broekmans, Andries C. Bloem, Jeroen F. van Velzen, Berris van Kessel, Inger S. Nijhof, Kris A. Frerichs, Jakub Krejcik
Supplemental Methods, Supplementary Tables, Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0452721a8c1ab9f0e419e4de516be385
https://doi.org/10.1158/1078-0432.22462592
https://doi.org/10.1158/1078-0432.22462592
Autor:
Niels W.C.J. van de Donk, Tuna Mutis, A. Kate Sasser, Henk M. Lokhorst, Torben Plesner, Christopher Chiu, Richard W.J. Groen, Pino J. Poddighe, René J.P. Musters, Johan van Meerloo, Sonja Zweegman, Marloes E.C. Broekmans, Andries C. Bloem, Jeroen F. van Velzen, Berris van Kessel, Inger S. Nijhof, Kris A. Frerichs, Jakub Krejcik
Monocytes take up AF488-labeled daratumumab-CD38 complexes from PKH-26-stained UM9 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230a4dcac28395ecc5fc3cc16b3eb690
https://doi.org/10.1158/1078-0432.22462577.v1
https://doi.org/10.1158/1078-0432.22462577.v1
Autor:
Niels W.C.J. van de Donk, Tuna Mutis, A. Kate Sasser, Henk M. Lokhorst, Torben Plesner, Christopher Chiu, Richard W.J. Groen, Pino J. Poddighe, René J.P. Musters, Johan van Meerloo, Sonja Zweegman, Marloes E.C. Broekmans, Andries C. Bloem, Jeroen F. van Velzen, Berris van Kessel, Inger S. Nijhof, Kris A. Frerichs, Jakub Krejcik
Daratumumab-mediated CD38 reduction of MM cells in the presence of PBMCs as shown by Western blot analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058adc8564febc80f981da9e7692cc1e
https://doi.org/10.1158/1078-0432.22462586.v1
https://doi.org/10.1158/1078-0432.22462586.v1
Autor:
Niels W.C.J. van de Donk, Tuna Mutis, A. Kate Sasser, Henk M. Lokhorst, Torben Plesner, Christopher Chiu, Richard W.J. Groen, Pino J. Poddighe, René J.P. Musters, Johan van Meerloo, Sonja Zweegman, Marloes E.C. Broekmans, Andries C. Bloem, Jeroen F. van Velzen, Berris van Kessel, Inger S. Nijhof, Kris A. Frerichs, Jakub Krejcik
Loss of CD38 from the MM cell membrane is associated with reduced CDC and ADCC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a3bd6823c4ef97e445cbca8c50e4be
https://doi.org/10.1158/1078-0432.22462589.v1
https://doi.org/10.1158/1078-0432.22462589.v1
Autor:
Niels W.C.J. van de Donk, Tuna Mutis, A. Kate Sasser, Henk M. Lokhorst, Torben Plesner, Christopher Chiu, Richard W.J. Groen, Pino J. Poddighe, René J.P. Musters, Johan van Meerloo, Sonja Zweegman, Marloes E.C. Broekmans, Andries C. Bloem, Jeroen F. van Velzen, Berris van Kessel, Inger S. Nijhof, Kris A. Frerichs, Jakub Krejcik
Purpose: Daratumumab treatment results in a marked reduction of CD38 expression on multiple myeloma cells. The aim of this study was to investigate the clinical implications and the underlying mechanisms of daratumumab-mediated CD38 reduction.Experim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc1ec2ca3e37165483ff0af7857d0b2
https://doi.org/10.1158/1078-0432.c.6525140
https://doi.org/10.1158/1078-0432.c.6525140