Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Pinku Mukherjee"'
Autor:
Mukulika Bose, Alexa Sanders, Aashna Handa, Aabha Vora, Manuel R. Cardona, Cory Brouwer, Pinku Mukherjee
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract MUC1 is a transmembrane glycoprotein that is overexpressed and aberrantly glycosylated in epithelial cancers. The cytoplasmic tail of MUC1 (MUC1 CT) aids in tumorigenesis by upregulating the expression of multiple oncogenes. Signal transduce
Externí odkaz:
https://doaj.org/article/22c57fbafd694eec8ce6d2ca282e580a
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/8f554f07c0174d80821f8836803b1d5a
Autor:
Mukulika Bose, Priyanka Grover, Alexa J. Sanders, Ru Zhou, Mohammad Ahmad, Sophia Shwartz, Priyanka Lala, Sritama Nath, Mahboubeh Yazdanifar, Cory Brouwer, Pinku Mukherjee
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Pancreatic ductal adenocarcinoma (PDA) is one of the most lethal human cancers. Transforming Growth Factor Beta (TGF-β) is a cytokine that switches from a tumor-suppressor at early stages to a tumor promoter in the late stages of tumor development,
Externí odkaz:
https://doaj.org/article/aafd6cb80a5d437b85b675c88c7a2832
Publikováno v:
Physiological Reports, Vol 9, Iss 3, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/3f09957b4e244c268cfa0cd875a7d297
Autor:
Ru Zhou, Mahboubeh Yazdanifar, Lopamudra Das Roy, Lynsey M. Whilding, Artemis Gavrill, John Maher, Pinku Mukherjee
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/38f6b535cf944d07aec4d1e55175eb60
Autor:
Shu-ta Wu, Anthony J. Fowler, Corey B. Garmon, Adam B. Fessler, Joshua D. Ogle, Kajal R. Grover, Bailey C. Allen, Chandra D. Williams, Ru Zhou, Mahboubeh Yazdanifar, Craig A. Ogle, Pinku Mukherjee
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-13 (2018)
Abstract Background Pancreatic ductal adenocarcinoma (PDA) remains the most aggressive cancers with a 5-year survival below 10%. Systemic delivery of chemotherapy drugs has severe side effects in patients with PDA and does not significantly improve o
Externí odkaz:
https://doaj.org/article/07bd40c201904f37a49e6060dca5f3bc
Autor:
Mahnaz Sahraei, Mukulika Bose, J. Alexa Sanders, Chandrav De, Lopamudra DasRoy, Sritama Nath, Cory R. Brouwer, Pinku Mukherjee
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5587 (2021)
Myeloid-derived suppressor cells (MDSCs) are immature myeloid cells that are responsible for immunosuppression in tumor microenvironment. Here we report the impact of mucin 1 (MUC1), a transmembrane glycoprotein, on proliferation and functional activ
Externí odkaz:
https://doaj.org/article/bd58a71729a948e8b1206c1da3054970
Autor:
Ru Zhou, Mahboubeh Yazdanifar, Lopamudra Das Roy, Lynsey M. Whilding, Artemis Gavrill, John Maher, Pinku Mukherjee
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Antibody-derived chimeric antigen receptor (CAR) T cell therapy has achieved gratifying breakthrough in hematologic malignancies but has shown limited success in solid tumor immunotherapy. Monoclonal antibody, TAB004, specifically recognizes the aber
Externí odkaz:
https://doaj.org/article/57b677a36b7045db9c944649c0b548c1
Autor:
Didier Dréau, Laura Jeffords Moore, Mike Wu, Lopa Das Roy, Lloye Dillion, Travis Porter, Rahul Puri, Noor Momin, K. Dane Wittrup, Pinku Mukherjee
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Immunotherapy regimens have shown success in subsets of cancer patients; however, their efficacy against pancreatic ductal adenocarcinoma (PDA) remain unclear. Previously, we demonstrated the potential of TAB004, a monoclonal antibody targeting the u
Externí odkaz:
https://doaj.org/article/0ff0a231afde4b4188e2a8e5fb5f02f8
Autor:
Jennifer M Curry, Dahlia M Besmer, Timothy K Erick, Nury Steuerwald, Lopamudra Das Roy, Priyanka Grover, Shanti Rao, Sritama Nath, Jacob W Ferrier, Robert W Reid, Pinku Mukherjee
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224309 (2019)
In recent years, vaccines against tumor antigens have shown potential for combating invasive cancers, including primary tumors and metastatic lesions. This is particularly pertinent for breast cancer, which is the second-leading cause of cancer-relat
Externí odkaz:
https://doaj.org/article/15f6f579b4ae4c04ac423dc647dfd330