Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Pinja Kettunen"'
Autor:
Ying-Chieh Wu, Šárka Lehtonen, Kalevi Trontti, Riitta Kauppinen, Pinja Kettunen, Ville Leinonen, Markku Laakso, Johanna Kuusisto, Mikko Hiltunen, Iiris Hovatta, Kristine Freude, Hiramani Dhungana, Jari Koistinaho, Taisia Rolova
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Background Patients with Alzheimer's disease (AD) frequently present with cerebral amyloid angiopathy (CAA), characterized by the accumulation of beta-amyloid (Aβ) within the cerebral blood vessels, leading to cerebrovascular dysfunction. P
Externí odkaz:
https://doaj.org/article/ff2355ab447b4ba585cb169fd9c26369
Autor:
Meike Hedwig Keuters, Velta Keksa-Goldsteine, Taisia Rõlova, Merja Jaronen, Pinja Kettunen, Aurora Halkoluoto, Gundars Goldsteins, Jari Koistinaho, Hiramani Dhungana
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Stroke is a leading cause of permanent disability worldwide. Despite intensive research over the last decades, key anti-inflammatory strategies that have proven beneficial in pre-clinical animal models have often failed in translation. The i
Externí odkaz:
https://doaj.org/article/e14cbe37fa6d42fea676aeada9103100
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-30 (2024)
Abstract Central nervous system infections have been suggested as a possible cause for neurodegenerative diseases, particularly sporadic cases. They trigger neuroinflammation which is considered integrally involved in neurodegenerative processes. In
Externí odkaz:
https://doaj.org/article/09f48696ee7d4fe1a343dcff230c3dcf
Autor:
Henna Jäntti, Minna Oksanen, Pinja Kettunen, Stella Manta, Lionel Mouledous, Hennariikka Koivisto, Johanna Ruuth, Kalevi Trontti, Hiramani Dhungana, Meike Keuters, Isabelle Weert, Marja Koskuvi, Iiris Hovatta, Anni-Maija Linden, Claire Rampon, Tarja Malm, Heikki Tanila, Jari Koistinaho, Taisia Rolova
Publikováno v:
Cells, Vol 11, Iss 24, p 4116 (2022)
The PSEN1 ΔE9 mutation causes a familial form of Alzheimer’s disease (AD) by shifting the processing of amyloid precursor protein (APP) towards the generation of highly amyloidogenic Aβ42 peptide. We have previously shown that the PSEN1 ΔE9 muta
Externí odkaz:
https://doaj.org/article/32d6b7b081a84028b01d9a606f0770d8
Autor:
Pinja Kettunen, Angelina Lesnikova, Noora Räsänen, Ravi Ojha, Leena Palmunen, Markku Laakso, Šárka Lehtonen, Johanna Kuusisto, Olli Pietiläinen, Saber H. Saber, Merja Joensuu, Olli P. Vapalahti, Jari Koistinaho, Taisia Rolova, Giuseppe Balistreri
2019 coronavirus disease (COVID-19) is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In addition to respiratory illness, COVID-19 patients exhibit neurological symptoms lasting from weeks to months (long COVID). It
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc61b8492bc339abf8705b258985d874
http://hdl.handle.net/10138/358045
http://hdl.handle.net/10138/358045
Autor:
Pinja Kettunen, Angelina Lesnikova, Noora Räsänen, Ravi Ojha, Leena Palmunen, Markku Laakso, Šárka Lehtonen, Johanna Kuusisto, Olli Pietiläinen, Olli P. Vapalahti, Jari Kostinaho, Taisia Rolova, Giuseppe Balistreri
COVID-19 is a disease caused by coronavirus SARS-CoV-2. In addition to respiratory illness, COVID-19 patients exhibit neurological symptoms that can last from weeks to months (long COVID). It is unclear whether these neurological manifestations are d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2065ed9f50a7246f3afc87344b4364c
https://doi.org/10.1101/2022.09.14.508057
https://doi.org/10.1101/2022.09.14.508057
The research on neurodegenerative disorders has long focused on neuronal pathology and used transgenic mice as disease models. However, our understanding of the chronic neurodegenerative process in the human brain is still very limited. It is increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208ff4aff79e335b1a846602f0bd18c1
http://hdl.handle.net/10138/337055
http://hdl.handle.net/10138/337055
Autor:
Wu, Ying-Chieh1 (AUTHOR), Lehtonen, Šárka1,2 (AUTHOR) sarka.lehtonen@uef.fi, Trontti, Kalevi1 (AUTHOR), Kauppinen, Riitta1 (AUTHOR), Kettunen, Pinja1 (AUTHOR), Leinonen, Ville3,4 (AUTHOR), Laakso, Markku4 (AUTHOR), Kuusisto, Johanna4,5 (AUTHOR), Hiltunen, Mikko6 (AUTHOR), Hovatta, Iiris7 (AUTHOR), Freude, Kristine8 (AUTHOR), Dhungana, Hiramani1 (AUTHOR), Koistinaho, Jari9,10 (AUTHOR) jari.koistinaho@helsinki.fi, Rolova, Taisia1 (AUTHOR) taisia.rolova@helsinki.fi
Publikováno v:
Fluids & Barriers of the CNS. 9/27/2024, Vol. 21 Issue 1, p1-20. 20p.
Autor:
Keuters, Meike Hedwig1,2 (AUTHOR), Keksa-Goldsteine, Velta2 (AUTHOR), Rõlova, Taisia1 (AUTHOR), Jaronen, Merja2 (AUTHOR), Kettunen, Pinja1 (AUTHOR), Halkoluoto, Aurora1 (AUTHOR), Goldsteins, Gundars2 (AUTHOR), Koistinaho, Jari1,2,3 (AUTHOR) jari.koistinaho@helsinki.fi, Dhungana, Hiramani1,2 (AUTHOR) hiramani.dhungana@helsinki.fi
Publikováno v:
Scientific Reports. 8/2/2024, Vol. 14 Issue 1, p1-14. 14p.
Autor:
Kettunen, Pinja1 (AUTHOR), Koistinaho, Jari1 (AUTHOR) jari.koistinaho@helsinki.fi, Rolova, Taisia1 (AUTHOR)
Publikováno v:
Journal of Neuroinflammation. 6/6/2024, Vol. 24, p1-30. 30p.