Liposomal nanoformulations with trans-caryophyllene and caryophyllene oxide: do they have an inhibitory action on the efflux pumps NorA, Tet(K), MsrA, and MepA?

Autor: Santana JEG; Departamento de Antibióticos, Universidade Federal de Pernambuco (UFPE), Recife, 50670 901, Pernambuco, Brazil., Oliveira-Tintino CDM; Departament of Biological Chemistry, Universidade Regional Do Cariri (URCA), Crato, 63105-010, Ceará, Brazil. Electronic address: datianemorais@hotmail.com., Alencar GG; Departament of Biological Chemistry, Universidade Regional Do Cariri (URCA), Crato, 63105-010, Ceará, Brazil., Siqueira GM; Departament of Biological Chemistry, Universidade Regional Do Cariri (URCA), Crato, 63105-010, Ceará, Brazil., Almeida-Bezerra JW; Departament of Biological Chemistry, Universidade Regional Do Cariri (URCA), Crato, 63105-010, Ceará, Brazil., Viana Rodrigues JP; Oswaldo Cruz Foundation (Fiocruz Ceará), Eusebio, 61773-270, Ceará, Brazil., Pinheiro Gonçalves VB; Oswaldo Cruz Foundation (Fiocruz Ceará), Eusebio, 61773-270, Ceará, Brazil., Nicolete R; Oswaldo Cruz Foundation (Fiocruz Ceará), Eusebio, 61773-270, Ceará, Brazil., Tintino SR; Departament of Biological Chemistry, Universidade Regional Do Cariri (URCA), Crato, 63105-010, Ceará, Brazil., Coutinho HDM; Departament of Biological Chemistry, Universidade Regional Do Cariri (URCA), Crato, 63105-010, Ceará, Brazil., Silva TGD; Departamento de Antibióticos, Universidade Federal de Pernambuco (UFPE), Recife, 50670 901, Pernambuco, Brazil.

Publikováno v: Chemico-biological interactions [Chem Biol Interact] 2024 Apr 25; Vol. 393, pp. 110945. Date of Electronic Publication: 2024 Mar 07.