Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Pingjuan Li"'
Autor:
Takele Argaw, Michael P. Marino, Andrew Timmons, Lindsey Eldridge, Kazuyo Takeda, Pingjuan Li, Anna Kwilas, Wu Ou, Jakob Reiser
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 670-680 (2021)
Despite their exceptional capacity for transgene delivery ex vivo, lentiviral (LV) vectors have been slow to demonstrate clinical utility in the context of in vivo applications. Unresolved safety concerns related to broad LV vector tropism have limit
Externí odkaz:
https://doaj.org/article/bb1aa2c91590406b93d2703125bf4eaa
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81131 (2013)
The in vitro differentiation of human induced pluripotent stem cells (hiPSC) to generate specific types of cells is inefficient, and the remaining undifferentiated cells may form teratomas. This raises safety concerns for clinical applications of hiP
Externí odkaz:
https://doaj.org/article/48c0fcea78e74d5ea8d92d01c109fd6b
Autor:
Yili Chen, Guoxiu Xiang, Pingjuan Liu, Xianling Zhou, Penghao Guo, Zhongwen Wu, Juhua Yang, Peisong Chen, Junqi Huang, Kang Liao
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 36, Iss , Pp 276-283 (2024)
ABSTRACT: Objectives: Resistance against ceftazidime-avibactam (CZA) in carbapenem-resistant Pseudomonas aeruginosa (CRPA) is emerging. This study was aimed at detecting the prevalence and molecular characteristics of CZA-resistant CRPA clinical isol
Externí odkaz:
https://doaj.org/article/93f4702d556740d098fe13bbe2750b48
Autor:
Michael P. Marino, Jakob Reiser, Takele Argaw, Jizhong Zou, Pingjuan Li, Brian Iaffaldano, Michael T Morreale
Publikováno v:
Human Gene Therapy Methods. 29:135-145
The adeno-associated virus serotype 2 (AAV2) Rep 78 protein, a strand-specific endonuclease (nickase) promotes site-specific integration of transgene sequences bearing homology arms corresponding to the AAVS1 safe harbor locus. To investigate the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d37229f636adbcc0580d5a3533c3689
https://doi.org/10.1089/hgtb.2018.052
https://doi.org/10.1089/hgtb.2018.052
Autor:
J. Keith Joung, Qin Liu, Benjamin P. Kleinstiver, Scott H. Greenwald, Mihoko Leon, Michelle S. Prew, Pingjuan Li, Eric A. Pierce, Daniel Navarro-Gomez
Treatment strategies for dominantly inherited disorders typically involve silencing or ablating the pathogenic allele. CRISPR/Cas nucleases have shown promise in allele-specific knockout approaches when the dominant allele creates unique protospacer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3379f7fefa5d4306db72656ad0d42541
Autor:
Yili Chen, Runshi Yang, Penghao Guo, Pingjuan Liu, Jiankai Deng, Zhongwen Wu, Qingping Wu, Junqi Huang, Kang Liao
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
BackgroundThe emergence of ceftazidime–avibactam (CZA) resistance among carbapenem-resistant Klebsiella pneumoniae (CRKP) is of major concern due to limited therapeutic options.MethodsIn this study, 10 CRKP strains were isolated from different samp
Externí odkaz:
https://doaj.org/article/c3655aeeb6d34109b2d9223780c6da85
Autor:
Yili Chen, Yao Chen, Pingjuan Liu, Penghao Guo, Zhongwen Wu, Yaqin Peng, Jiankai Deng, Yannan Kong, Yingpeng Cui, Kang Liao, Bin Huang
Publikováno v:
BMC Geriatrics, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background Bloodstream infection (BSI) caused by carbapenem resistant Klebsiella pneumoniae (CRKP), especially in elderly patients, results in higher morbidity and mortality. The purpose of this study was to assess risk factors associated wi
Externí odkaz:
https://doaj.org/article/51af2d9d6e4c4a528fcad204c6c7f1e5
Publikováno v:
Molecular medicine reports. 9(2)
The present study aimed to investigate genetic and environmental factors involved in the pathogenesis of congenital heart disease (CHD). A total of 61 familial pedigrees with CHD were analyzed, and 134 patients out of 761 family members had a diagnos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3dca4886746ca9e98d3f4f2534cb88e
https://pubmed.ncbi.nlm.nih.gov/24337398
https://pubmed.ncbi.nlm.nih.gov/24337398
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81131 (2013)
PLoS ONE
PLoS ONE
The in vitro differentiation of human induced pluripotent stem cells (hiPSC) to generate specific types of cells is inefficient, and the remaining undifferentiated cells may form teratomas. This raises safety concerns for clinical applications of hiP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d3c204b888d71777c4c9267cfb1e3b0
http://europepmc.org/articles/PMC3843684?pdf=render
http://europepmc.org/articles/PMC3843684?pdf=render