Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Pingguo Liu"'
Autor:
Wenfeng Ren, Zilong Xu, Yating Chang, Fei Ju, Hongning Wu, Zhiqi Liang, Min Zhao, Naizhen Wang, Yanhua Lin, Chenhang Xu, Shengming Chen, Yipeng Rao, Chaolong Lin, Jianxin Yang, Pingguo Liu, Jun Zhang, Chenghao Huang, Ningshao Xia
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract PD-1 is a co-inhibitory receptor expressed by CD8+ T cells which limits their cytotoxicity. PD-L1 expression on cancer cells contributes to immune evasion by cancers, thus, understanding the mechanisms that regulate PD-L1 protein levels in c
Externí odkaz:
https://doaj.org/article/4aa031597255428f8b54ad3f2aa3e667
Autor:
Rui Wang, Xiao Peng, Yixin Yuan, Baojie Shi, Yuan Liu, Hengxiao Ni, Wenzhi Guo, Qiwei Yang, Pingguo Liu, Jie Wang, Zhaojie Su, Shengnan Yu, Dehua Liu, Jinyan Zhang, Junjie Xia, Xueni Liu, Hao Li, Zhengfeng Yang, Zhihai Peng
Publikováno v:
The Innovation, Vol 5, Iss 3, Pp 100599- (2024)
Elucidating the temporal process of immune remodeling under immunosuppressive treatment after liver transplantation (LT) is critical for precise clinical management strategies. Here, we performed a single-cell multi-omics analysis of peripheral blood
Externí odkaz:
https://doaj.org/article/55c575f009f44537ba33cc793f350174
SPTAN1/NUMB axis senses cell density to restrain cell growth and oncogenesis through Hippo signaling
Autor:
Dongxue Su, Yuxi Li, Weiji Zhang, Huan Gao, Yao Cheng, Yongqiang Hou, Junhong Li, Yi Ye, Zhangjian Lai, Zhe Li, Haitao Huang, Jiaxin Li, Jinhuan Li, Mengyu Cheng, Cheng Nian, Na Wu, Zhien Zhou, Yunzhi Xing, Yu Zhao, He Liu, Jiayu Tang, Qinghua Chen, Lixin Hong, Wengang Li, Zhihai Peng, Bin Zhao, Randy L. Johnson, Pingguo Liu, Wanjin Hong, Lanfen Chen, Dawang Zhou
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 20 (2023)
The loss of contact inhibition is a key step during carcinogenesis. The Hippo–Yes-associated protein (Hippo/YAP) pathway is an important regulator of cell growth in a cell density–dependent manner. However, how Hippo signaling senses cell density
Externí odkaz:
https://doaj.org/article/10851ccf1c0d4b83bc5cb1bf57cbefc0
Autor:
Ping Guo, Hailing Zheng, Yihan Li, Yuntong Li, Yue Xiao, Jin Zheng, Xingqiang Zhu, Huan Xu, Zhi He, Qian Zhang, Jinchun Chen, Mingshan Qiu, Min Jiang, Pingguo Liu, Hongliang Chen
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract Background Epigenetic variants carried by circulating tumor DNA can be used as biomarkers for early detection of hepatocellular carcinoma (HCC) by noninvasive liquid biopsy. However, traditional methylation analysis method, bisulfite sequenc
Externí odkaz:
https://doaj.org/article/dd47e1dabedd4009af95bdd5b133f241
Autor:
Enkang Zhang, Chaozhang Yu, Hui Tang, Yuntong Li, Dongliang Zuo, Rongshui Yang, Chao Ma, Jiayin Miao, Pingguo Liu, Xinhui Su
Publikováno v:
ACS Omega, Vol 5, Iss 30, Pp 19014-19019 (2020)
Externí odkaz:
https://doaj.org/article/626c1f212dc342349e84547065a7bed4
Autor:
Yong Luo, Chaolong Lin, Wenfeng Ren, Fei Ju, Zilong Xu, Huiling Liu, Zeng Yu, Jun Chen, Jun Zhang, Pingguo Liu, Chenghao Huang, Ningshao Xia
Publikováno v:
Molecular Therapy: Oncolytics, Vol 15, Iss , Pp 153-165 (2019)
As a clinical setting in which novel treatment options are urgently needed, hepatocellular carcinoma (HCC) exhibits intriguing opportunities for oncolytic virotherapy. Here we report the rational generation of a novel herpes simplex virus type 1 (HSV
Externí odkaz:
https://doaj.org/article/10c90f1f5f7d4610b5c8d9c36f3cd6db
Autor:
Jie Li, Song You, Sheng Zhang, Qing Hu, Fuqiang Wang, Xiaoqin Chi, Wenxiu Zhao, Chengrong Xie, Changmao Zhang, Yaqi Yu, Jianmin Liu, Yue Zhao, Pingguo Liu, Yi Zhang, Xujin Wei, Qiu Li, Xiaomin Wang, Zhenyu Yin
Publikováno v:
Molecular Oncology, Vol 13, Iss 9, Pp 1993-2009 (2019)
The cross‐talk between hepatic stellate cells (HSCs) and hepatic carcinoma cells contributes to hepatocellular carcinoma (HCC) progression, but the underlying mechanism is largely unknown. We report here that activated HSCs induce upregulation of n
Externí odkaz:
https://doaj.org/article/35d9ee006df14e2680aee211bf6e7899
Tumor-targeting oncolytic virus elicits potent immunotherapeutic vaccine responses to tumor antigens
Autor:
Yong Luo, Chaolong Lin, Yidi Zou, Fei Ju, Wenfeng Ren, Yanhua Lin, Yale Wang, Xiaoxuan Huang, Huiling Liu, Zeng Yu, Pingguo Liu, Guowei Tan, Quan Yuan, Jun Zhang, Chenghao Huang, Ningshao Xia
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Oncolytic viruses represent a promising therapeutic modality, but they have yet to live up to their therapeutic potential. Safety and efficacy concerns impel us to identify least toxic oncolytic agents that would generate durable and multifaceted ant
Externí odkaz:
https://doaj.org/article/5c1b40be09524b148970e38227da0751
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-12 (2017)
Abstract Background Increasing evidence indicates that abnormal expression of GABPA is associated with tumor development and progression. However, the function and clinicopathological significance of GABPA in hepatocellular carcinoma (HCC) remain obs
Externí odkaz:
https://doaj.org/article/10edaab0162e471d92b9552f6e96be12
Autor:
Jiaxuan, Zhang, Yang, Zhou, Dongliang, Zuo, Limin, Yang, Xiaowen, Yan, Pingguo, Liu, Qiuquan, Wang
Publikováno v:
Analytical and Bioanalytical Chemistry. 414:257-263
Selenium (Se) is a mysterious thus tempting element playing a dual bio-chemical function, mainly through selenol, during life processes. Quantification of the selenols is thus of great significance for understanding the biological roles of Se, but re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c0f4a2347404487f4c4afeb1416b041
https://doi.org/10.1007/s00216-021-03772-z
https://doi.org/10.1007/s00216-021-03772-z