Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Pinggang Ding"'
Autor:
Chunyan Gu, Yajun Wang, Lulin Zhang, Li Qiao, Shanliang Sun, Miaomiao Shao, Xiaozhu Tang, Pinggang Ding, Chao Tang, Yuhao Cao, Yanyan Zhou, Mengjie Guo, Rongfang Wei, Nianguang Li, Yibei Xiao, Jinao Duan, Ye Yang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/60981aa57de3419294bc8419b6f812fa
Autor:
Ying Chen, Jinjun Qian, Pinggang Ding, Wang Wang, Xinying Li, Xiaozhu Tang, Chao Tang, Ye Yang, Chunyan Gu
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-14 (2022)
Abstract Human sideroflexin 2 (SFXN2) belongs to the SFXN protein family, which is a mitochondrial outer membrane protein involved in mitochondrial iron metabolism. Mitochondria are indispensable for cellular energy production and iron metabolism. Ho
Externí odkaz:
https://doaj.org/article/00bcc52bccb6416aa27b531f52936018
Autor:
Xiaozhu Tang, Zhendong Deng, Pinggang Ding, Wanting Qiang, Yue Lu, Shengyao Gao, Ye Hu, Ye Yang, Juan Du, Chunyan Gu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-15 (2022)
Abstract Backgroud Multiple myeloma (MM) is an incurable plasma cell malignancy in the bone marrow (BM), while immunoglobulin D type of MM (IgD MM) is a very rare but most severe subtype in all MM cases. Therefore, systemic study on IgD MM is purpose
Externí odkaz:
https://doaj.org/article/4ec203a765474a01bb06b9776b0f9c9b
Autor:
Chunyan Gu, Yajun Wang, Lulin Zhang, Li Qiao, Shanliang Sun, Miaomiao Shao, Xiaozhu Tang, Pinggang Ding, Chao Tang, Yuhao Cao, Yanyan Zhou, Mengjie Guo, Rongfang Wei, Nianguang Li, Yibei Xiao, Jinao Duan, Ye Yang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-14 (2022)
Abstract Background Currently, multiple myeloma (MM) is still an incurable plasma cell malignancy in urgent need of novel therapeutic targets and drugs. Methods Bufalin was known as a highly toxic but effective anti-cancer compound. We used Bufalin a
Externí odkaz:
https://doaj.org/article/ae3d76e7c1924ac494159517a84e8a2a
Autor:
Xiaozhu Tang, Mengjie guo, Pinggang Ding, Zhendong Deng, Mengying Ke, Yuxia Yuan, Yanyan Zhou, Zigen Lin, Muxi Li, Chunyan Gu, Xiaosong Gu, Ye Yang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-13 (2021)
Abstract Multiple myeloma (MM) is an incurable plasma cell malignancy in the bone marrow characterized by chromosome instability (CIN), which contributes to the acquisition of heterogeneity, along with MM progression, drug resistance, and relapse. In
Externí odkaz:
https://doaj.org/article/3e9ba81ec9474168b4be1295ef0db76e
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The potential to overcome resistance to proteasome inhibitors is greatly related with ubiquitin-proteasome system during multiple myeloma (MM) treatment process. The constitutive photomorphogenic 1 (RFWD2), referred to an E3 ubiquitin ligase, has bee
Externí odkaz:
https://doaj.org/article/59da5d680dd24f90b93544a02d132871
Autor:
Pinggang Ding, Mengjie Guo, Ye Yang, Xiaosong Gu, Mengying Ke, Zhendong Deng, Xiaozhu Tang, Muxi Li, Zigen Lin, Chunyan Gu, Yuxia Yuan, Yanyan Zhou
Publikováno v:
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-13 (2021)
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-13 (2021)
Multiple myeloma (MM) is an incurable plasma cell malignancy in the bone marrow characterized by chromosome instability (CIN), which contributes to the acquisition of heterogeneity, along with MM progression, drug resistance, and relapse. In this stu
Publikováno v:
Drug Design, Development and Therapy. 13:1947-1956
Purpose: We aimed to prepare two oral drug delivery systems consisting of polyoxyl 15 hydroxystearate (HS15) with pluronicF127 (F127) and HS15 with pluronicL61 (L61) to overcome the challenges of genistein's poor oral bioavailability. This provides a
Publikováno v:
Journal of Pharmacy and Pharmacology. 71:765-773
Objectives To increase the solubility of baicalein (BAI) by preparing BAI-micelles (BAI-M) with Solutol HS15 (HS15) and Poloxamer 188 (F68), thereby improving its oral bioavailability. Methods Baicalein micelles were prepared with HS15 and F68 by thi
Publikováno v:
Drug Development and Industrial Pharmacy. 44:1536-1542
Genistein (GEN), is a natural dietary isoflavone, has been reported to show anticancer activities. However, its poor aqueous solubility and oral bioavailability limit its clinical application. We designed a novel genistein-loaded mixed micelles (GEN-