Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Pingfu Hou"'
Autor:
Yan Wang, Yihao Wang, Chunjie Wu, Yunfei Ji, Pingfu Hou, Xueqing Wu, Zhongwei Li, Minle Li, Sufang Chu, Qianqian Ning, Bo Xu, Junnian Zheng, Jin Bai
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-15 (2024)
Abstract The metastasis of non-small cell lung cancer (NSCLC) is the leading death cause of NSCLC patients, which requires new biomarkers for precise diagnosis and treatment. Circular RNAs (circRNAs), the novel noncoding RNA, participate in the progr
Externí odkaz:
https://doaj.org/article/a30998d7c9d2448f802dae2129c0da6b
Autor:
Qianqing Wang, Fang Chen, Yu He, Yue Gao, Jiawen Wang, Sufang Chu, Pei Xie, Jiateng Zhong, Haixia Shan, Jin Bai, Pingfu Hou
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109158- (2024)
Summary: Polypyrimidine tract-binding protein 3 (PTBP3) plays an important role in the post-transcriptional regulation of gene expression, including mRNA splicing, translation, and stability. Increasing evidence has shown that PTBP3 promotes cancer p
Externí odkaz:
https://doaj.org/article/c9a11c3c40304ee89eab8b45ac6e531b
Autor:
Zhiying Shao, Wendong Yang, Xiannan Meng, Minle Li, Pingfu Hou, Zhongwei Li, Sufang Chu, Junnian Zheng, Jin Bai
Publikováno v:
Cancer Medicine, Vol 12, Iss 10, Pp 11177-11190 (2023)
Abstract Background Yin Yang‐1 (YY1) is identified as a transcription factor with multiple functions. However, the role of YY1 in tumorigenesis remains controversial and its regulatory effects may depend upon not only cancer types, but also its int
Externí odkaz:
https://doaj.org/article/48fc82e5a16f4b6a8867f4845fb2f7e2
Autor:
Xintian Chen, Hongmei Yong, Miaolei Chen, Chuyin Deng, Pengfei Wang, Sufang Chu, Minle Li, Pingfu Hou, Junnian Zheng, Zhongwei Li, Jin Bai
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-18 (2023)
Abstract Background Metabolic reprogramming is a hallmark of various cancers. Targeting metabolic processes is a very attractive treatment for cancer. Renal cell carcinoma (RCC) is a type of metabolic disease, and the lipidomic profile of RCC is sign
Externí odkaz:
https://doaj.org/article/8818b040f3e44e0b9d736d0bee6ff682
Autor:
Minle Li, Xue Zhao, Hongmei Yong, Jian Xu, Pengfei Qu, Shuxi Qiao, Pingfu Hou, Zhongwei Li, Sufang Chu, Junnian Zheng, Jin Bai
Publikováno v:
Cell Death and Disease, Vol 13, Iss 2, Pp 1-12 (2022)
Abstract Transketolase (TKT) which is an important metabolic enzyme in the pentose phosphate pathway (PPP) participates in maintaining ribose 5-phosphate levels. TKT is necessary for maintaining cell growth. However, we found that in addition to this
Externí odkaz:
https://doaj.org/article/2393ad07b4424cb39842a0dc10cf9e55
Expanding uncapped translation and emerging function of circular RNA in carcinomas and noncarcinomas
Autor:
Yan Wang, Chunjie Wu, Yu Du, Zhongwei Li, Minle Li, Pingfu Hou, Zhigang Shen, Sufang Chu, Junnian Zheng, Jin Bai
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-22 (2022)
Abstract Circular RNAs (circRNAs) are classified as noncoding RNAs because they are devoid of a 5’ end cap and a 3’ end poly (A) tail necessary for cap-dependent translation. However, increasing numbers of translated circRNAs identified through h
Externí odkaz:
https://doaj.org/article/ea1792377a944d6785e657dc0bdccd19
Autor:
Zhongwei Li, Diandian Wang, Xintian Chen, Wenwen Wang, Pengfei Wang, Pingfu Hou, Minle Li, Sufang Chu, Shuxi Qiao, Junnian Zheng, Jin Bai
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-11 (2021)
Abstract Protein arginine methyltransferase 1 (PRMT1) is able to promote breast cancer cell proliferation. However, the detailed mechanisms of PRMT1-mediated breast cancer cell proliferation are largely unknown. In this study, we reveal that PRMT1-me
Externí odkaz:
https://doaj.org/article/10f93ae2b56e468c977ccd8ea25e918e
Autor:
Xintian Chen, Menghan Cao, Pengfei Wang, Sufang Chu, Minle Li, Pingfu Hou, Junnian Zheng, Zhongwei Li, Jin Bai
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tripartite motif containing-21 (TRIM21), an E3 ubiquitin ligase, was initially found to be involved in antiviral responses and autoimmune diseases. Recently studies have reported that TRIM21 plays a dual role in cancer promoting and suppressing in th
Externí odkaz:
https://doaj.org/article/ddec381d5df540f78671b521fb74b050
Autor:
Pingfu Hou, Sen Meng, Minle Li, Tian Lin, Sufang Chu, Zhongwei Li, Junnian Zheng, Yuming Gu, Jin Bai
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-18 (2021)
Abstract Background Increasing studies have shown that long noncoding RNAs (lncRNAs) are pivotal regulators participating in carcinogenic progression and tumor metastasis in colorectal cancer (CRC). Although lncRNA long intergenic noncoding RNA 460 (
Externí odkaz:
https://doaj.org/article/361f23f76b894e26852133084018164e
Autor:
Zhongwei Li, Minle Li, Diandian Wang, Pingfu Hou, Xintian Chen, Sufang Chu, Dafei Chai, Junnian Zheng, Jin Bai
Publikováno v:
Cell & Bioscience, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Enhancer of zeste homolog 2 (EZH2), as a main component of Polycomb Repressive Complex 2, catalyzes histone H3K27me3 to silence its target gene expression. EZH2 upregulation results in cancer development and poor prognosis of cancer patients
Externí odkaz:
https://doaj.org/article/121491637c0749468563963588de7d74