Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Pingfang Tian"'
Publikováno v:
Annals of Microbiology, Vol 72, Iss 1, Pp 1-13 (2022)
Abstract Purpose Overproduction of desired metabolites usually sacrifices cell growth. Here we report that quorum sensing (QS) can be exploited to coordinate cell growth and lactic acid production in Escherichia coli. Methods We engineered two QS str
Externí odkaz:
https://doaj.org/article/89782148d103423a9facf7032a29f257
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
The recent decline of the international biodiesel industry has led to decreased production and therefore increased the price of glycerol, which is a major by-product of biodiesel but a substrate for production of 3-hydroxypropionic acid (3-HP), that
Externí odkaz:
https://doaj.org/article/d6293eaa67d2472e971e7f4d642fcaaa
Publikováno v:
Microbial Cell Factories, Vol 19, Iss 1, Pp 1-13 (2020)
Abstract Background One major mission of microbial breeding is high-level production of desired metabolites. Overproduction of intermediate metabolites in core pathways is challenging as it may impair cell growth and viability. Results Here we report
Externí odkaz:
https://doaj.org/article/7b178dbfffca4a3b955c74c784a6215d
Autor:
Ziling Xu, Pingfang Tian
Publikováno v:
Molecules, Vol 28, Iss 6, p 2761 (2023)
Aclacinomycin A (ACM-A) is an anthracycline antitumor agent widely used in clinical practice. The current industrial production of ACM-A relies primarily on chemical synthesis and microbial fermentation. However, chemical synthesis involves multiple
Externí odkaz:
https://doaj.org/article/98979de601344cd3903a739602d0f20b
Publikováno v:
Microbial Cell Factories, Vol 17, Iss 1, Pp 1-12 (2018)
Abstract Background Klebsiella pneumoniae is a promising industrial species for bioproduction of bulk chemicals such as 1,3-propanediol, 2,3-butanediol and 3-hydroxypropionic acid (3-HP). However, lactic acid is a troublesome by-product when optimizi
Externí odkaz:
https://doaj.org/article/4d3092453ca444c3a1cd9d0884bf5e41
Publikováno v:
Synthetic and Systems Biotechnology, Vol 2, Iss 3, Pp 219-225 (2017)
Derived from the bacterial adaptive immune system, CRISPR technology has revolutionized conventional genetic engineering methods and unprecedentedly facilitated strain engineering. In this review, we outline the fundamental CRISPR tools that have bee
Externí odkaz:
https://doaj.org/article/b9f8c86fb1f94e7a9cea481e9e50dd8e
Publikováno v:
Applied Microbiology and Biotechnology. 106:6383-6396
Transposons are mobile genetic elements that can give rise to gene mutation and genome rearrangement. Due to their mobility, transposons have been exploited as genetic tools for modification of plants, animals, and microbes. Although a plethora of re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c97ba9f37bf5433a613585a60c03a4b6
https://doi.org/10.1007/s00253-022-12170-z
https://doi.org/10.1007/s00253-022-12170-z
Publikováno v:
International Journal of Pest Management. :1-10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce6fa28ba28a921e19c87b1fa05b3f30
https://doi.org/10.1080/09670874.2022.2055807
https://doi.org/10.1080/09670874.2022.2055807
Publikováno v:
Zemdirbyste-Agriculture. 108:117-124
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f375d949b2ba1c73de103449b924a8da
https://doi.org/10.13080/z-a.2021.108.015
https://doi.org/10.13080/z-a.2021.108.015
Publikováno v:
Metabolic Engineering. 65:30-41
One grand challenge for bioproduction of desired metabolites is how to coordinate cell growth and product synthesis. Here we report that a tryptophan operon-assisted CRISPR interference (CRISPRi) system can switch glycerol oxidation and reduction pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dcdad8708c25f470d36607f6e26db59
https://doi.org/10.1016/j.ymben.2021.03.001
https://doi.org/10.1016/j.ymben.2021.03.001