Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Pingchang, Yang"'
Autor:
Xiangqian Luo, Jinna Yang, Haoyue Zheng, Yuanyi Zhang, Lihua Mo, Qinmiao Huang, Gaohui Wu, Jianwen Zhong, Yu Liu, Gui Yang, Pingchang Yang
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Improvement is needed in the remedies used to control Th2 polarization. Bioengineering approaches have modified immune cells that have immunosuppressive functions. This study aims to generate modified eosinophils (Meos) in vivo an
Externí odkaz:
https://doaj.org/article/d1f0c1625ba34597a6878481205f4d83
Autor:
Simeng Liu, Huayuan Xi, Xia Xue, Xiangdong Sun, Huang Huang, Dongjun Fu, Yang Mi, Yongzheng He, Pingchang Yang, Youcai Tang, Pengyuan Zheng
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Background Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder that has been found to be associated with dysregulation of gastrointestinal functions and gut microbial homeostasis (the so-called “gut-brain axis”). ASD
Externí odkaz:
https://doaj.org/article/dae1c8c833dd4120940f46c2cd30bf5f
Autor:
Xuejie Xu, Lihua Mo, Yun Liao, Kaitlyn Song Zhang, Hanqing Zhang, Le Liu, Yu Liu, Aifa Tang, Pingchang Yang, Xiaoyu Liu
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background To elucidate the mechanism of dysfunction of tolerogenic dendritic cells (DCs) is of significance. Telomerase involves the regulation of the cell fate and activities. The objective of this study is to investigate the role of telom
Externí odkaz:
https://doaj.org/article/e9cfcee60cd04ff8885bcdf5a8a6eefc
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110067- (2024)
Summary: Dendritic cells (DC) play a crucial role in the initiation of immune responses. TRIM41, an E3 ubiquitin ligase, can facilitate targeting protein degradation. The purpose of this study is to analyze the role of TRIM41 in the pathogenesis of a
Externí odkaz:
https://doaj.org/article/129e5062009e45a0b3aba1b3d9692379
Autor:
Xianhai Zeng, Juanjuan Li, Jiangqi Liu, Lihua Mo, Yu Liu, Aizhi Zhang, Pingchang Yang, Hui Kong
Publikováno v:
Innate Immunity, Vol 30 (2024)
Th2 polarization is essential for the pathogenesis of allergic rhinitis (AR). Th2 polarization's mechanism requires further understanding. IL-4 is the primary cytokine involved in Th2 response. Fibroblasts play a role in immune regulation. This study
Externí odkaz:
https://doaj.org/article/b0bf2984c13f45e7a79189feb05f0cc9
Autor:
Aizhi Zhang, Lihua Mo, Xiaoxue Chen, Ping Tang, Yu Liu, Wenkai Zhang, Cheng Zhang, Cailing Wang, Huanping Zhang, Pingchang Yang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116510- (2024)
Background: CpG oligodeoxynucleotide (CpG-ODN; CpG, in short) has been employed as an adjuvant in allergen specific immunotherapy (AIT) to treat allergic diseases. The underlying mechanism needs to be further explained. The aim of this study is to ex
Externí odkaz:
https://doaj.org/article/0fe7c1714ab64a91a661e86a81d726c4
Autor:
Dan Peng, Juan Li, Yin Li, Lingling Bai, Anying Xiong, Xiang He, Xiaolan Li, Qin Ran, Lei Zhang, Manling Jiang, Junyi Wang, Elaine Lai-Han Leung, Pingchang Yang, Guoping Li
Publikováno v:
Pharmacological Research, Vol 200, Iss , Pp 107070- (2024)
Fibrotic hypersensitivity pneumonitis (FHP) is a fatal interstitial pulmonary disease with limited treatment options. Lung macrophages are a heterogeneous cell population that exhibit distinct subsets with divergent functions, playing pivotal roles i
Externí odkaz:
https://doaj.org/article/7768b464e5c54cda910ed841daae94fa
Autor:
Jinmei Xue, Zhizhen Liu, Yun Liao, Xiwen Zhang, Yu Liu, Lihua Mo, Rui Dong, Qiang Li, Xizhuo Sun, Jun Xie, Pingchang Yang
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108615- (2024)
Summary: Telomeres are an important biomarker in the cell destiny. The relationship between telomeres and regulatory T cells (Tregs) has not yet been investigated. The objective of this study is to evaluate the link between Tregs' telomere length and
Externí odkaz:
https://doaj.org/article/e4b78430b5d74416918901007122f3e6
Autor:
Shuyao Qiu, Xiangqian Luo, Lihua Mo, Shuang Zhang, Yun Liao, Li Guan, Liteng Yang, Qinmiao Huang, Dabo Liu, Pingchang Yang
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-11 (2022)
Abstract Allergen-specific immunotherapy (AIT) is the main treatment for allergic diseases. The therapeutic efficacy of AIT has to be improved. Neuropeptides, such as TAFA4, have immune-regulating features. The objective of this study is to promote t
Externí odkaz:
https://doaj.org/article/dc63e9b78a454480980f6db1784604d3
Autor:
Manling Jiang, Haiqiong Yu, Li Luo, Lei Zhang, Anying Xiong, Junyi Wang, Qianhui Wang, Yao Liu, Shengbin Liu, Ying Xiong, Pingchang Yang, Christopher Chang, Jianquan Zhang, Xiang He, Guoping Li
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 19, Iss 2 (2023)
A good safety and immunogenicity profile was reported in Phase I and II clinical trials of inactivated SARS-CoV-2 vaccines. Here, we report two cases associated with vaccine-associated adverse events, including one patient with fever and another with
Externí odkaz:
https://doaj.org/article/f911958422be444bb4414dd29a7ea90c