Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Ping-pui Wong"'
Autor:
Lei-Bo Xu, Yu-Fei Qin, Liangping Su, Cheng Huang, Qiuping Xu, Rui Zhang, Xiang-De Shi, Ruipu Sun, Jiali Chen, Zhixiao Song, Xue Jiang, Lihuan Shang, Gang Xiao, Xiangzhan Kong, Chao Liu, Ping-Pui Wong
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Bile duct tumor thrombosis (BDTT) is a complication mostly observed in patients with advanced hepatocellular carcinoma (HCC), causing jaundice and associated with poor clinical outcome. However, its underlying molecular mechanism is unclear.
Externí odkaz:
https://doaj.org/article/989b3c333055480bbc337d72722b9df3
Autor:
Liangping Su, Sangqing Wu, Cheng Huang, Xianhua Zhuo, Jiali Chen, Xue Jiang, Xiangzhan Kong, Cui Lv, Qiuping Xu, Ping Han, Xiaoming Huang, Ping-Pui Wong
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-17 (2023)
Abstract Conventional chemotherapy targets malignant cells without evaluating counter protection from the tumor microenvironment that often causes treatment failure. Herein, we establish chemoresistant fibroblasts (rCAFs) as regulators of neoadjuvant
Externí odkaz:
https://doaj.org/article/c312675dcc8942f4a32e6a2f157e4064
Autor:
Hongquan Qin, Jiali Chen, Katia Bouchekioua-Bouzaghou, Ya-Ming Meng, Jordi Bach Griera, Xue Jiang, Xiangzhan Kong, Minghui Wang, Qiuping Xu, Ping-Pui Wong
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-22 (2023)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is characterised by limited responses to chemoimmunotherapy attributed to highly desmoplastic tumor microenvironment. Disrupting the tumor-stromal cell crosstalk is considered as an improved
Externí odkaz:
https://doaj.org/article/57f8cb11ec2f4207954cfdc131aa223a
Autor:
Sangqing Wu, Cheng Huang, Liangping Su, Ping‐Pui Wong, Yongsheng Huang, Renhui Chen, Peiliang Lin, Yuchu Ye, Pang Song, Ping Han, Xiaoming Huang
Publikováno v:
Cancer Medicine, Vol 12, Iss 5, Pp 6388-6400 (2023)
Abstract Background Head and neck squamous cell carcinomas (HNSCC) are the most common type of head and neck cancer with an unimproved prognosis over the past decades. Although the role of cancer‐associated‐fibroblast (CAF) has been demonstrated
Externí odkaz:
https://doaj.org/article/7132e730882546a2825fb48d2515a062
Autor:
Ya-Ming Meng, Xue Jiang, Xinbao Zhao, Qiong Meng, Sangqing Wu, Yitian Chen, Xiangzhan Kong, Xiaoyi Qiu, Liangping Su, Cheng Huang, Minghui Wang, Chao Liu, Ping-Pui Wong
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Pericyte-endothelial cells interaction defines tumor vasculature and has implications in tumorigenesis development and therapy efficacy. Here, the authors show that hexokinase 2- driven glycolysis activates ROCK1-MLC2 mediated contractility in pericy
Externí odkaz:
https://doaj.org/article/0fc81aa026fd4a01921523679ed90330
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Pericytes (PCs), known as mural cells, play an important blood vessel (BV) supporting role in regulating vascular stabilization, permeability and blood flow in microcirculation as well as blood brain barrier. In carcinogenesis, defective interaction
Externí odkaz:
https://doaj.org/article/c39932c4ac824cecb37f8963b3b8e4aa
Autor:
Qiong Meng, Xueting Hu, Xinbao Zhao, Xiangzhan Kong, Ya-Ming Meng, Yitian Chen, Liangping Su, Xue Jiang, Xiaoyi Qiu, Cheng Huang, Chao Liu, Minghui Wang, Ping-Pui Wong
Publikováno v:
EBioMedicine, Vol 66, Iss , Pp 103301- (2021)
Background: Sphingolipid metabolism is among the top dysregulated pathways in non-small cell lung carcinomas (NSCLC). However, the molecular control of sphingolipid metabolic reprogramming in cancer progression remains unclear. Methods: We first dete
Externí odkaz:
https://doaj.org/article/65dc3b90f2494a00bf54b5b46f5dc6e0
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8369 (2010)
p300 functions as a transcriptional co-activator to regulate many cellular responses such as cell growth, transformation, development and differentiation. It has been shown to affect the transcriptional activity of p53 which regulates p21(Waf1/CIP1)
Externí odkaz:
https://doaj.org/article/3bd5f51f04a54468b90d13d5b3f0de0d
Autor:
Sangqing Wu, Cheng Huang, Liangping Su, Ping‐Pui Wong, Yongsheng Huang, Renhui Chen, Peiliang Lin, Yuchu Ye, Pang Song, Ping Han, Xiaoming Huang
Publikováno v:
Cancer Medicine. 12:6388-6400
Head and neck squamous cell carcinomas (HNSCC) are the most common type of head and neck cancer with an unimproved prognosis over the past decades. Although the role of cancer-associated-fibroblast (CAF) has been demonstrated in HNSCC, the correlatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::729231f4b615701521ca6433bc6ce82b
https://doi.org/10.1002/cam4.5383
https://doi.org/10.1002/cam4.5383
Autor:
Xianhua Zhuo, Cheng Huang, Liangping Su, Faya Liang, Wenqian Xie, Qiuping Xu, Ping Han, Xiaoming Huang, Ping-Pui Wong
Publikováno v:
Journal of Cancer Research and Clinical Oncology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baa28720200e36e46a555096e0decdc5
https://doi.org/10.1007/s00432-023-04848-2
https://doi.org/10.1007/s00432-023-04848-2