Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ping-Zhong Tan"'
Autor:
Ronald M. Baldwin, N. S. Kula, Gilles Tamagnan, Robert B. Innis, Ping-Zhong Tan, Ross J. Baldessarini, Xing Fu
Publikováno v:
Journal of Medicinal Chemistry. 45:2319-2324
A series of 4'-substituted phenyl-4-piperidinylmethanol and benzoyl-4-piperidine derivatives was synthesized as potential novel serotonin 5-HT2A receptor ligands that can be radiolabeled for in vivo brain imaging. Compounds were prepared by alkylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e514a1d25725df931155a5a036d2cb
https://doi.org/10.1021/jm0200411
https://doi.org/10.1021/jm0200411
Autor:
Julie K. Staley, Pradeep K. Garg, Masahiro Fujita, Sami S. Zoghbi, Lou Amici, Ping Zhong Tan, Xing Fu, Robert Soufer, Robert B. Innis, John Seibyl, Ronald M. Baldwin, Christopher H. van Dyck, Jair C. Soares
Publikováno v:
Psychiatry Research: Neuroimaging. 106:81-93
The test/retest reproducibility of brain measures of 5-HT2A receptors with positron emission tomography (PET) and [ 18 F]deuteroaltanserin was examined in a group of eight healthy human subjects. PET measures of 5-HT2A receptors were obtained under a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::807af079c40ff15a60a37e4229657cdf
https://doi.org/10.1016/s0925-4927(01)00071-3
https://doi.org/10.1016/s0925-4927(01)00071-3
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 42:457-467
F-18 and H-2 dual-labeled altanserin (3, [18F]d-ALT), a novel PET tracer for 5-HT2A receptors with metabolically resistant properties, was synthesized by [18F]fluoride displacement of the corresponding deuterated nitro precursor in 32% yield (EOB) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b362e0f8b6bc30df5494401e5bd345a8
https://doi.org/10.1002/(sici)1099-1344(199905)42:5<457::aid-jlcr206>3.0.co
https://doi.org/10.1002/(sici)1099-1344(199905)42:5<457::aid-jlcr206>3.0.co
Publikováno v:
ChemInform. 34
A one-pot and efficient conversion of aryl- and acyl-substituted methyl alcohols into the corresponding chlorides is described, which involved tosylation with tosyl chloride and triethylamine in the presence of a catalytic amount of 4-(dimethylamino)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa5ec9e2821d15bc3b440c4a77957678
https://doi.org/10.1002/chin.200337027
https://doi.org/10.1002/chin.200337027
Autor:
Ping-Zhong Tan, Pradeep K. Garg, Quinn Ramsby, Chin Ng, Christopher H. van Dyck, Robert B. Innis, Robert Soufer, Mohammed S Al Tikriti, Julie K. Staley, Heide Klump, Ronald M. Baldwin
Publikováno v:
Nuclear medicine and biology. 28(3)
The regional distribution in brain, distribution volumes, and pharmacological specificity of the PET 5-HT(2A) receptor radiotracer [(18)F]deuteroaltanserin were evaluated and compared to those of its non-deuterated derivative [(18)F]altanserin. Both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f8e7d73ca0ef5d8a325fc4ddcd6033
https://pubmed.ncbi.nlm.nih.gov/11323237
https://pubmed.ncbi.nlm.nih.gov/11323237
Autor:
Ping Zhong Tan, John Seibyl, Julie K. Staley, Robert B. Innis, Pradeep K. Garg, Dennis S. Charney, Louis Amici, Ronald M. Baldwin, Christopher H. van Dyck, Jair C. Soares, Xing Fu
Publikováno v:
Nuclear medicine and biology. 27(8)
ABSTRACT. [ 18 F]Altanserin has emerged as a promising positron emission tomography (PET) ligand for serotonin-2A (5-HT 2A ) receptors. The deuterium substitution of both of the 2′-hydrogens of altanserin ([ 18 F]deuteroaltanserin) yields a metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c896929c1b7d7752c77f915157ffa213
https://pubmed.ncbi.nlm.nih.gov/11150702
https://pubmed.ncbi.nlm.nih.gov/11150702
Autor:
Robert Soufer, Lawrence H. Staib, Ping Zhong Tan, Chin K. Ng, Ronald M. Baldwin, Yolanda Zea-Ponce, Dennis S. Charney, J. Douglas Bremner, Sami S. Zoghbi, Robert B. Innis, John Seibyl, Andrew G. Horti
Publikováno v:
Psychiatry research. 91(2)
Although positron emission tomography (PET) and single photon emission computed tomography (SPECT) are increasingly used for quantitation of neuroreceptor binding, almost no studies to date have involved a direct comparison of the two. One study foun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2938de9d7926a0ff2c260feff033079
https://pubmed.ncbi.nlm.nih.gov/10515463
https://pubmed.ncbi.nlm.nih.gov/10515463
Autor:
Robert B. Innis, Ping-Zhong Tan, Pradeep K. Garg, Dennis S. Charney, Ronald M. Baldwin, Robert Soufer
Publikováno v:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 50(5)
A complete remote control system was constructed for production of the PET 5-HT2A ligand [18F]altanserin by nitro-for-fluoro exchange. Comparing with published methods, the key features include (1) conducting azeotropic distillation and nucleophilic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee0ce07af01439838b11b190a1d5273
https://pubmed.ncbi.nlm.nih.gov/10214711
https://pubmed.ncbi.nlm.nih.gov/10214711
Autor:
van Dyck, Christopher H., Ping-Zhong Tan, Baldwin, Ronald M., Amici, Louis A., Garg, Pradeep K., Ng, Chin K., Soufer, Robert, Charney, Dennis S., Innis, Robert B.
Publikováno v:
Journal of Nuclear Medicine; Feb2000, Vol. 41 Issue 2, p234-241, 8p, 1 Color Photograph, 3 Charts, 3 Graphs