Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ping-Ping H. Lee"'
Autor:
Ming Ting Lee, Chang Jen Huang, Jiuan Jiuan Hwang, Ying Tang Huang, Amy Y.L. Lee, Ferng Chun Ke, Lung Ta Lee, Ping Ping H. Lee, Chithan C. Kandaswami
Publikováno v:
Biochemical Pharmacology. 67:2103-2114
Focal adhesion kinase (FAK), a member of a growing family of structurally distinct protein tyrosine kinases (PTK), has been linked to specific phosphorylation events, and the elevation of FAK activity in human carcinoma cells correlated with increase
Publikováno v:
Journal of Cellular Physiology. 188:75-88
The extracellular matrix (ECM) is an important regulator of mammary epithelial cell (MEC) function and is remodeled by matrix metalloproteinases (MMPs). To investigate the significance and regulation of MMP activity in normal MEC, we utilized a prima
Publikováno v:
Endocrinology. 141:3764-3773
Tissue remodeling is a key process involved in normal mammary gland development, with matrix metalloproteinases (MMPs) playing an important role in this process. Our laboratory has demonstrated that tumor necrosis factor (TNF) stimulates branching mo
Autor:
Danilo Zangani, Lawrence Mead, Roberta Megan, Suzanne F. Shoemaker, Kathleen M. Darcy, Anuradha Mudipalli, Wendy K. Shea-Eaton, Ping-Ping H. Lee, Margot M. Ip
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 36:578-592
Stromal-epithelial interactions play a profound role in regulating normal and tumor development in the mammary gland. The molecular details of these events, however, are incompletely understood. A novel serum-free transwell coculture system was devel
Autor:
Chang-Jen Huang, Lily Chen, Ferng Chun Ke, Sui-Wen Lin, Margot M. Ip, Jiuan Jiuan Hwang, Ping-Ping H. Lee, Ming-Ting Lee
Publikováno v:
Clinical and Experimental Metastasis. 18:493-499
The present study investigated the modulatory role of transforming growth factor beta 1 (TGFβ1) on the secretion of matrix metalloproteinases (MMPs) and tested whether the altered secretion of MMPs could directly affect the invasive behavior of ovar
Autor:
Linda M. Varela, Danilo Zangani, Joy A. Russell, Patricia A. Masso-Welch, Ruea-Yea Huang, Margot M. Ip, Mary M. Vaughan, Ping-Ping H. Lee, Ann L. Wohlhueter, Suzanne F. Shoemaker, Elizabeth Horn, Kathleen M. Darcy
Publikováno v:
Europe PubMed Central
Epidermal growth factor (EGF) is a multifunctional regulator of mammary epithelial cells (MEC) that transduces its signals through the EGF receptor (EGFR). To clarify the role of the EGFR in the mammary gland, EGFR expression, localization and functi
Publikováno v:
Journal of Cellular Physiology. 163:365-379
The mechanisms of action of, and resistance to, the steroidal regulators of normal mammary epithelial and breast cancer cell development are only partially understood. A major obstacle to research progress has been the difficulty in supporting physio
Publikováno v:
Endocrinology. 136:1707-1717
The ability of retinoids to modulate the proliferation as well as the morphological and functional differentiation of normal mammary epithelial cells isolated from pubescent female virgin rats was evaluated in serum-free primary culture. The retinobe
Autor:
Wen-Te, Kao, Chun-Yu, Lin, Lung-Ta, Lee, Ping-Ping H, Lee, Chin-Chun, Hung, Yung-Sheng, Lin, Shih-Hsun, Chen, Ferng-Chun, Ke, Jiuan-Jiuan, Hwang, Ming-Ting, Lee
Publikováno v:
Anticancer research. 28(4B)
In this study, highly invasive tumor cell lines (designated A431-I, -II and -III) derived from parental A431 tumor cells (A431-P) were isolated by three successive passages through a Boyden chamber with matrigel-coated membrane support. The invasive
Publikováno v:
Anticancer research. 25(3B)
Focal adhesion kinase (FAK), a member of a growing family of structurally distinct protein tyrosine kinases (PTK), has been linked to specific phosphorylation events, and the elevation of FAK activity in human carcinoma cells is associated with incre