Breakthroughs in modern cancer therapy and elusive cardiotoxicity: Critical research-practice gaps, challenges, and insights

Autor: Jin Li, Ping-Pin Zheng, Johan M. Kros

Publikováno v: Medicinal Research Reviews, 38(1), 325-376. John Wiley & Sons Inc.
Medicinal Research Reviews

To date, five cancer treatment modalities have been defined. The three traditional modalities of cancer treatment are surgery, radiotherapy, and conventional chemotherapy, and the two modern modalities include molecularly targeted therapy (the fourth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ada6496ef083e9652470bd3236c303
https://pure.eur.nl/en/publications/a3abe07b-d0f0-47e2-971c-b09f9dbc7332

Fast Tracking of Co-Localization of Multiple Markers by Using the Nanozoomer Slide Scanner and NDPViewer

Autor: Ping-Pin Zheng, Johan M. Kros, Marcel van der Weiden

Publikováno v: Journal of Cellular Physiology. 229:967-973

The detection of co-localization of immunohistochemical markers in tissues or cells requires the application of the confocal laser scanning microscope (CLSM) to multiple immunofluorescence (MIF) stainings. CLSM is operationally sophisticated but requ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e8bf8970a89c6bf894f67d0cdbec4bcd
https://doi.org/10.1002/jcp.24538

Intratumoral, not circulating, endothelial progenitor cells share genetic aberrations with glial tumor cells

Autor: Ping-Pin Zheng, Johan M. Kros, Arnaud J P E Vincent, Peter J. van der Spek, Marcel van der Weiden

Publikováno v: Journal of Cellular Physiology, 228(7), 1383-1390. Wiley-Liss Inc.

Literature data indicate that glioma stem cells may give rise to both tumor cells and endothelial progenitor cells (EPCs). Malignant glioma patients usually have increased levels of circulating (EPCs) and these cells are known to contribute to the gl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae281b3efec9cafafdb99f69dfed5d90
https://doi.org/10.1002/jcp.24309

Expression Sites of Colligin 2 in Glioma Blood Vessels

Autor: Marcel van der Weiden, Dana A M Mustafa, Ping-Pin Zheng, Theo M. Luider, Johan M. Kros, Alex L. Nigg

Publikováno v: Brain Pathology. 20:50-65

In a previous study using state-of-the-art proteomic techniques, we identified colligin 2 (HSP47) as a glioma blood vessel-specific protein. In the present study we precisely localized the expression of colligin 2 in the blood vessels of diffusely in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::97eb59ff9ef071e99ad85254f8f66013
https://doi.org/10.1111/j.1750-3639.2008.00248.x

Intratumoral distribution of 1p loss in oligodendroglial tumors

Autor: Marcel van der Weiden, Johan M. Kros, Ping-Pin Zheng, Wim C. J. Hop, Martin J. van den Bent, Mathilde C.M. Kouwenhoven

Publikováno v: Kros, J M, van der Weiden, M, Zheng, P-P, Hop, W C, van den Bent, M J & Kouwenhoven, M C M 2007, ' Intratumoral distribution of 1p loss in oligodendroglial tumors ', Journal of Neuropathology and Experimental Neurology, vol. 66, no. 12, pp. 1118-23 . https://doi.org/10.1097/nen.0b013e31815c254d
Journal of Neuropathology and Experimental Neurology, 66(12), 1118-23. Lippincott Williams and Wilkins
Journal of Neuropathology and Experimental Neurology, 66(12), 1118-1123. Oxford University Press

The favorable response of oligodendrogliomas correlates well with characteristic chromosomal losses, of which loss of the short arm of chromosome 1 is most predictive. Oligodendrogliomas are histopathologically heterogeneous tumors and, in addition t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a51e73a9c118fb92432ba427e94e1b6
https://doi.org/10.1097/nen.0b013e31815c254d