Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Ping-Jin Gao"'
Autor:
Ling-Ran Kong, Xiao-Hui Chen, Qing Sun, Kai-Yuan Zhang, Lian Xu, Liliqiang Ding, Yan-Ping Zhou, Ze-Bei Zhang, Jing-Rong Lin, Ping-Jin Gao
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 112078- (2023)
Summary: Complement activation is thought to underline the pathologic progression of obesity-related metabolic disorders; however, its role in adaptive thermogenesis has scarcely been explored. Here, we identify complement C3a receptor (C3aR) and C5a
Externí odkaz:
https://doaj.org/article/0d162e93ec2e4719b7a6db7410b0dc11
Autor:
Zhiyuan Zheng, Ya-nan Li, Shanfen Jia, Mengting Zhu, Lijuan Cao, Min Tao, Jingting Jiang, Shenghua Zhan, Yongjing Chen, Ping-Jin Gao, Weiguo Hu, Ying Wang, Changshun Shao, Yufang Shi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The formation of the pre-metastatic niche enables the colonisation of disseminated cancer cells in distant organs. Here, the authors show that Th2 cytokines induce Complement 3 production in lung mesenchymal stromal cells, which recruits neutrophils
Externí odkaz:
https://doaj.org/article/156f0ce9dbfa4a79ac075c19ee86e1cd
Autor:
Linghui Kong, Xiaofeng Tang, Yuanyuan Kang, Lei Dong, Jianhua Tong, Jianzhong Xu, Ping-jin Gao, Ji-guang Wang, Weili Shen, Limin Zhu
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundAdrenal venous sampling (AVS) is recognized as the gold standard for subtyping primary aldosteronism (PA), but its invasive nature and technical challenges limit its availability. A recent study reported that sodium chloride cotransporter (
Externí odkaz:
https://doaj.org/article/eb6c9123f5774949a35b8b2d1d49983f
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
A 29-year-old female patient diagnosed with primary aldosteronism (PA) in 2004 underwent complete adrenalectomy for left aldosterone-producing adenoma (APA) confirmed by hematoxylin and eosin (HE) and CYP11B2 staining. Her hypokalemia was corrected,
Externí odkaz:
https://doaj.org/article/dbe4e4741efe4f7aa307d39b3adb7087
Autor:
Yue‐Tong Guo, Yuan‐Yuan Lu, Xiao Lu, Shun He, Shi‐Jin Li, Shuai Shao, Han‐Dan Zhou, Rui‐Qi Wang, Xiao‐Dong Li, Ping‐Jin Gao
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 16 (2021)
Background Adventitial remodeling is a pathological hallmark of hypertension that results in target organ damage. Activated adventitial fibroblasts have emerged as critical regulators in this process, but the precise mechanism remains unclear. Method
Externí odkaz:
https://doaj.org/article/8f1d33dddb4e4a8ebbf4eeee285450a8
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Cardiac remodeling consisted of ventricular hypertrophy and interstitial fibrosis is the pathological process of many heart diseases. Fibroblasts as one of the major cells in the myocardium regulate the balance of the generation and degeneration of c
Externí odkaz:
https://doaj.org/article/b60602a1aab847dbab560d0a733501bd
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Brown adipose tissue (BAT), consisted of brown adipocytes and stromal vascular fraction, which includes endothelial cells, lymphocytes, fibroblasts and stem cells, plays a vital role in regulating cardiovascular health and diseases. As a thermogenic
Externí odkaz:
https://doaj.org/article/c9f85f5d90cd4d81a835694d8c99e076
Autor:
Xiao-Xi Pan, Kang-Li Yao, Yong-Feng Yang, Qian Ge, Run Zhang, Ping-Jin Gao, Cheng-Chao Ruan, Fang Wu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Aging-associated chronic inflammation is a key contributing factor to a cluster of chronic metabolic disorders, such as cardiovascular disease, obesity, and type 2 diabetes. Immune cells particularly T cells accumulate in adipose tissue with advancin
Externí odkaz:
https://doaj.org/article/8f728be5c8b84284bf5228bcae5fbf24
Autor:
Zong-Jie Fu, Zhi-Yu Wang, Lian Xu, Xiao-Hui Chen, Xiang-Xiao Li, Wei-Tang Liao, Hong-Kun Ma, Meng-Di Jiang, Ting-Ting Xu, Jing Xu, Yan Shen, Bei Song, Ping-Jin Gao, Wei-Qing Han, Wen Zhang
Publikováno v:
Redox Biology, Vol 36, Iss , Pp 101671- (2020)
In the present study, we hypothesized that hypoxia-inducible factor 1α (HIF-1α)-mediated mitophagy plays a protective role in ischemia/reperfusion (I/R)-induced acute kidney injury (AKI). Mitophagy was evaluated by measuring the changes of mitophag
Externí odkaz:
https://doaj.org/article/a2105e25cbe04627a88238cf4bb8b3a8
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
It has been demonstrated that serum/glucocorticoid regulated kinase 1 (SGK1) and the downstream transcription factor forkhead box O1 (FoxO1) plays a critical role in the differentiation of T helper 17 cells/regulatory T cells (Th17/Treg). In the pres
Externí odkaz:
https://doaj.org/article/e7333a49d72d49a39abc726bd7bcb956