Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ping-Jie Xiao"'
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25667 (2011)
NSSR1 (Neural salient serine/arginine rich protein 1, alternatively SRp38) is a newly identified RNA splicing factor and predominantly expressed in neural tissues. Here, by Western blot analysis and immunofluorescent staining, we showed that the expr
Externí odkaz:
https://doaj.org/article/d733ccaead6e4df5b6fd5743a030e6b7
Perinuclear retention of viral particles is a poorly understood phenomenon observed during many virus infections. In this study, we investigated whether perinuclear accumulation acts as a barrier to limit recombinant adeno-associated virus (rAAV) tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d0bc9573be5f2cd1d9ba87969cb7634
Autor:
R. Jude Samulski, Ping Jie Xiao
Publikováno v:
Journal of Virology. 86:10462-10473
Understanding adeno-associated virus (AAV) trafficking is critical to advance our knowledge of AAV biology and exploit novel aspects of vector development. Similar to the case for most DNA viruses, after receptor binding and entry, AAV traverses the
Publikováno v:
Therapeutic Delivery. 3:835-856
Gene therapy is gaining momentum as a method of treating human disease. Initially conceived as a strategy to complement defective genes in monogenic disorders, the scope of gene therapy has expanded to encompass a variety of applications. Likewise, t
Publikováno v:
Molecular Therapy. 20(2):317-328
Trafficking through a variety of cellular structures and organelles is essential for the interaction between gene-delivery vectors (i.e., adeno-associated virus (AAV) and liposomes) and host cells/tissues. Here, we present a method of computer-assist
Publikováno v:
Tumor Biology. 32:359-366
Neural salient serine/arginine-rich protein 1 (NSSR1) has been found to play important roles in inhibiting alternative splicing during heat shock and mitosis and is predominantly expressed in neural tissues such as cerebral neurons, cerebellar Purkin
Publikováno v:
Molecular Reproduction and Development. 74:1363-1372
Neural salient serine/arginine rich protein 1 (NSSR1, alternatively SRp38) is a newly identified splicing factor that is highly expressed in neural and reproductive tissues. We showed that the expression of testicular NSSR1 increased significantly du
Autor:
Kevin Mensah-Biney, Nikita Patel, J. Justin Milner, Melinda A. Beck, Scott D. Neidich, Ping-jie Xiao, Michael G. Hudgens
Publikováno v:
The FASEB Journal. 28
Vaccination with influenza vaccine is the best method to prevent or lessen infection with influenza virus. While obesity is an independent risk factor for developing severe influenza infection, the...
Autor:
Melinda A. Beck, Ping-jie Xiao, J. Justin Milner, Heather A. Paich, Jennifer Rebeles, Terry L. Noah, Justin Paulson, Michael G. Hudgens
Publikováno v:
The FASEB Journal. 28
Obesity is a global health concern and more than one-third of the adult population in the United States is obese. Childhood obesity is also on the rise, with obesity rates doubling in children over the past 30 years and tripling in adolescents. Obese
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 108(34)
Molecular knockdown of disease proteins and restoration of wild-type activity represent a promising but challenging strategy for the treatment of diseases that result from the accumulation of misfolded proteins (i.e., Huntington disease, amyotrophic