Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ping Siu Kee"'
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Pharmacogenetics has potential for optimizing use of psychotropics. CYP2D6 and CYP2C19 are two clinically relevant pharmacogenes in the prescribing of antidepressants. Using cases recruited from the Understanding Drug Reactions Using Genomic Sequenci
Externí odkaz:
https://doaj.org/article/3623a848f0ca4a34bc4b5d83abfbc690
Autor:
Leonie M. Hitchman, Allamanda Faatoese, Tony R. Merriman, Allison L. Miller, Yusmiati Liau, Oscar E. E. Graham, Ping Siu Kee, John F. Pearson, Tony Fakahau, Vicky A. Cameron, Martin A. Kennedy, Simran D. S. Maggo
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
The enzyme cytochrome P450 2D6 (CYP2D6) metabolises approximately 25% of commonly prescribed drugs, including analgesics, anti-hypertensives, and anti-depressants, among many others. Genetic variation in drug metabolising genes can alter how an indiv
Externí odkaz:
https://doaj.org/article/31bf328d92e841b595815f8222e23b23
Autor:
Ping Siu Kee, Simran D. S. Maggo, Martin A. Kennedy, Murray L. Barclay, Allison L. Miller, Klaus Lehnert, Maurice A. Curtis, Richard L. M. Faull, Remai Parker, Paul K. L. Chin
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Omeprazole is extensively used to manage gastroesophageal reflux disease (GERD). It is primarily metabolized by CYP2C19. The CYP2C19*17 (rs12248560) allele and the recently described CYP2C:TG haplotype (rs11188059 and rs2860840) are associated with i
Externí odkaz:
https://doaj.org/article/1a6d85326f064630b4559320e165eea4
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Statins, a class of lipid-lowering medications, have been a keystone treatment in cardiovascular health. However, adverse effects associated with statin use impact patient adherence, leading to statin discontinuation. Statin-induced myotoxicity (SIM)
Externí odkaz:
https://doaj.org/article/d7a68f67e49943179bbeeff94ca8546a
Publikováno v:
Biochimie. 197:130-143
Polymerase chain reaction is an important tool in molecular biology. Although the principles of the technique are relatively simple, amplifying complex or long DNA segments can be challenging. A variety of PCR additives are used to improve the perfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a56aee4f0b1deaef7b29a8169780281
https://doi.org/10.1016/j.biochi.2022.02.009
https://doi.org/10.1016/j.biochi.2022.02.009
Autor:
Hitchman, Leonie M., Faatoese, Allamanda, Merriman, Tony R., Miller, Allison L., Yusmiati Liau, Graham, Oscar E. E., Ping Siu Kee, Pearson, John F., Fakahau, Tony, Cameron, Vicky A., Kennedy, Martin A., Maggo, Simran D. S.
Publikováno v:
Frontiers in Genetics; 10/13/2022, Vol. 13, p1-8, 8p
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Frontiers in Genetics
Frontiers in Genetics
Statins, a class of lipid-lowering medications, have been a keystone treatment in cardiovascular health. However, adverse effects associated with statin use impact patient adherence, leading to statin discontinuation. Statin-induced myotoxicity (SIM)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::651cbb4674c54c1ba927261c3ac8ba3a
https://www.frontiersin.org/article/10.3389/fgene.2020.575678/full
https://www.frontiersin.org/article/10.3389/fgene.2020.575678/full