Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Ping C Lee"'
Autor:
Aaron J. McLeod, Scott T. Ueda, Ping C. Lee, Jeff Spiegelman, Ravindra Kanjolia, Mansour Moinpour, Jacob Woodruff, Andrew C. Kummel
Publikováno v:
Thin Solid Films. 768:139717
Akademický článek
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Autor:
Ping C Lee, Michael K Petri
Publikováno v:
Journal of Pediatric Gastroenterology and Nutrition. 40:461-466
Background: The rat stomach undergoes major developmental changes postnatally. An antral mucosal protein (AMP-18) with in vitro mitogenic activity has recently been found in the mammalian stomach. Methods: To evaluate the role of AMP-18 in gastric de
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 288:E314-E320
Neonatal hypoxia leads to clinically significant fatty liver, presumably due to disturbances in lipid metabolism. To fully evaluate lipid metabolism, the present study analyzed the complete lipid profile of the brain, liver, and ingested stomach cont
Publikováno v:
Endocrinology. 145:5364-5372
Neonatal hypoxia is a common condition resulting from pulmonary and/or cardiac dysfunction. Dexamethasone therapy is a common treatment for many causes of neonatal distress, including hypoxia. The present study examined the effects of dexamethasone t
Autor:
Christa Picchiottino, Ping C. Lee
Publikováno v:
Toxicology Letters. 136:173-181
Since a number of food and food products contain 2,4-hexadienal (HX), an unsaturated aldehyde, human exposure to HX is likely. Long term HX feeding to rodents induces forestomach cancers. Aldehyde dehydrogenases (ALDH) are key enzymes in the stomach
Publikováno v:
Journal of Pediatric Gastroenterology and Nutrition. 34:542-547
Background: Glucocorticoids profoundly affect pancreatic development during the suckling period. Increases in circulating glucocorticoids during exposure to hypoxia may alter the normal pattern of pancreatic enzyme development. Methods: Rats were exp
Publikováno v:
Toxicology Letters. 99:117-126
The in vitro metabolism of [ 14 C]-nonylphenols (NPs) by rat hepatic microsomes in vitro was examined. Product formation was NADPH dependent and inhibited by the cytochrome P450 inhibitors, piperonyl butoxide and SKF525. Hepatic microsomes isolated f
Publikováno v:
Biochemical Pharmacology. 52:885-889
Both estradiol and nonylphenol (NP) inhibited hepatic microsomal 7-ethoxyresorufin O-deethylase (EROD) activity of β-naphthoflavone-treated rats. Enzyme kinetic analyses (Lineweaver-Burk plots) using different estradiol and NP concentrations with gr
Publikováno v:
Xenobiotica. 26:831-838
1. In in vitro assays, nonylphenol (NP) inhibited microsomal 5 alpha-reductase and steroid hydroxylase activities from the liver of dexamethasone-treated rats. The inhibition was specific in that 6 beta-hydroxylase was affected the most followed by 1