Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ping Ar Yang"'
Autor:
Ping Ar Yang, Tuomo A. Keinänen, Thresia Thomas, Hui-Chen Hsu, Shali John, Thekkumkat Thomas, Mervi T. Hyvönen
Publikováno v:
Amino Acids. 48:2293-2302
Tamoxifen is the most widely used drug to treat women with estrogen receptor α (ERα)-positive breast cancer. Endoxifen is recognized as the active metabolite of tamoxifen in humans. We studied endoxifen effects on ERα-positive MCF-7 breast cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc2792f36d25c5eeba4abbd8066fc06
https://doi.org/10.1007/s00726-016-2300-6
https://doi.org/10.1007/s00726-016-2300-6
Autor:
Huang-Ge Zhang, Hui-Chen Hsu, Horst Bluethmann, Jian Shi, John D. Mountz, Di Liu, Tong Zhou, Ping Ar Yang
Publikováno v:
Mechanisms of Ageing and Development. 122:305-326
We previously reported that T cells from aged mice were resistant to activation-induced cell death (AICD) in vitro. To determine whether the presence of AICD-resistant T cells is associated with defects in age-related peripheral clonal deletion in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e579fbd38cc642dd58afbef20cf966
https://doi.org/10.1016/s0047-6374(00)00247-5
https://doi.org/10.1016/s0047-6374(00)00247-5
Autor:
John D. Mountz, Tong Zhou, Di Liu, Winfried Wintersberger, Martin Fleck, Huang-Ge Zhang, Jingping Xie, Gwan Gyu Song, Ping Ar Yang, Carl K. Edwards, Hui-Chen Hsu
Publikováno v:
Arthritis & Rheumatism. 44:2146-2159
Objective To determine whether defective T cell apoptosis is associated with the development of a chronic arthritis subsequent to mycoplasma infection, and to determine whether deletion of T cells can prevent the development of this arthritis. Method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::766ac34342f8cf623fec89d3debc888b
https://doi.org/10.1002/1529-0131(200109)44:9<2146::aid-art368>3.0.co
https://doi.org/10.1002/1529-0131(200109)44:9<2146::aid-art368>3.0.co
Autor:
F. Nicole Standberry, Qi Wu, Karri S. Hawley, James P. DeLany, Henry Rothschild, Eric Ravussin, Sangkyu Kim, Ping Ar Yang, Paula J. Geiselman, Lynn B. Gerald, Scott W. Herke, S. Michal Jazwinski, Beth Kimball, Hui-Chen Hsu, John D. Mountz, Meghan Black, Robert H. Wood, Valentina Greco, Harry W. Schroeder, Hui-Yi Lin, Madlyn I. Frisard, Yu Wen Chiu, Mark A. Batzer, Annie Cooper, Crystal P. Traylor, Evest A. Broussard, Beth Schmidt, Laurie Byerley, Donald K. Scott, Elizabeth T. H. Fontham, Li Li, W. Andrew Deutsch, Yolanda Robertson, L. Joseph Su, Kay Lopez, Pauline A. Callinan, Pili Zhang, Darla E. Kendzor, Katie E. Cherry, Juling Zhou
Publikováno v:
Mechanisms of ageing and development. 127(3)
The nonagenarian population by definition represents individuals who have demonstrated success in aging. We determined the status of CD8(+) T-cell senescence in nonagenarians by analyzing the expression of CD28 and Fas (CD95), and analyzing activatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9083fa7a1249db21faecfc530127d215
https://pubmed.ncbi.nlm.nih.gov/16313945
https://pubmed.ncbi.nlm.nih.gov/16313945
Autor:
Zhongyu Liu, Xin Xu, Hui-Chen Hsu, Albert Tousson, Ping-Ar Yang, Qi Wu, Cunren Liu, Shaohua Yu, Huang-Ge Zhang, John D. Mountz
Publikováno v:
The Journal of clinical investigation. 112(9)
Previously, we described an APC-adenovirus (APC-Ad) FasL cell gene therapy method which could be used to deplete autoreactive T cells in vivo. FasL was toxic, however, and controlled regulation of FasL was not achieved. Here we describe an improved a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea6b5114835bd51b033ae6716ce6c60
https://pubmed.ncbi.nlm.nih.gov/14597758
https://pubmed.ncbi.nlm.nih.gov/14597758
Publikováno v:
Immunity. 2(4)
Protein tyrosine dephosphorylation after Fas cross-linking occurred In Fas apoptosis-sensitive CEM-6 cells but not in Fas apoptosis-resistant MOLT-4 cells, and apoptosis in the CEM-6 cells could be inhibited by the protein tyrosine phosphatase inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1bc59b67ca73ecaf9e83e3a4baaf764
https://pubmed.ncbi.nlm.nih.gov/7536621
https://pubmed.ncbi.nlm.nih.gov/7536621
Publikováno v:
The Journal of Immunology. 184:87.24-87.24
Abnormal inflammation and apoptosis are major pathogenic features of synovial fibroblasts (SF) in rheumatoid arthritis (RA). Fucosylation, an important type of glycosylation, has been identified in cancer and inflammation conditions. The role of fuco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e16d5d5ae16a440668e29636d6a120b9
https://doi.org/10.4049/jimmunol.184.supp.87.24
https://doi.org/10.4049/jimmunol.184.supp.87.24
Publikováno v:
The Journal of Immunology. 184:135.29-135.29
The severity of rheumatoid arthritis (RA) correlates with the activation and abundance of macrophages in the inflamed tissues and circulation. The purpose of this study is to generate a humanized mouse (hu/mo) DR5 transgenic (Tg) mouse in which the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b565b0a4ca73fec4cc7cfdcfe573807
https://doi.org/10.4049/jimmunol.184.supp.135.29
https://doi.org/10.4049/jimmunol.184.supp.135.29
Publikováno v:
The Journal of Immunology. 182:41.9-41.9
DR5 is a pro-apoptotic protein considered as a target for cancer and autoimmune therapy. An anti-human DR5 antibody, TRA-8, has been shown to induce apoptosis in various cells. The purpose of this study is to generate a humanized mouse DR5 molecule t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3e69cfd705da57f6a5be172a6e31247
https://doi.org/10.4049/jimmunol.182.supp.41.9
https://doi.org/10.4049/jimmunol.182.supp.41.9
Autor:
Zhongvu Liu, Willa A.1, Xin Xu1, Hui-Chcn Hsu, Willa A.1, Tousson, Albert2, Ping-Ar Yang, Albert1, Qi Wu1, Cunrea Liu, Albert1, Sliaohua Yu, Albert1, Huang-Ge Zhang, Albert1,3, Mountz, John D.1,3 john.mountz@ccc.uab.edu
Publikováno v:
Journal of Clinical Investigation. Nov2003, Vol. 112 Issue 9, p1332-1341. 10p.