Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Ping‐Kun Zhou"'
Autor:
Jiaojiao Zhu, Xingkun Ao, Yuhao Liu, Shenghui Zhou, Yifan Hou, Ziyan Yan, Lin Zhou, Huixi Chen, Ping Wang, Xinxin Liang, Dafei Xie, Shanshan Gao, Ping-Kun Zhou, Yongqing Gu
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background Although recent studies provide mechanistic understanding to the pathogenesis of radiation induced lung injury (RILI), rare therapeutics show definitive promise for treating this disease. Type II alveolar epithelial cells (AECII)
Externí odkaz:
https://doaj.org/article/6b573e0103dc4aeab44bcd19f8b32275
Publikováno v:
MedComm, Vol 5, Iss 10, Pp n/a-n/a (2024)
Abstract Radiation‐induced tissue injury (RITI) is the most common complication in clinical tumor radiotherapy. Due to the heterogeneity in the response of different tissues to radiation (IR), radiotherapy will cause different types and degrees of
Externí odkaz:
https://doaj.org/article/46e49251eaf549fc8784e47619d28f55
Autor:
Shi Chen, Da-Fei Xie, Saiyu Li, Jinhua Luo, Yang Han, Hejiang Guo, Shuaining Gao, Xin Huang, Hua Guan, Ruixue Huang, Ping-Kun Zhou
Publikováno v:
Cell Death and Disease, Vol 15, Iss 3, Pp 1-10 (2024)
Abstract Metabolic reprogramming, a hallmark of cancer, is closely associated with tumor development and progression. Changes in glycolysis play a crucial role in conferring radiation resistance to tumor cells. How radiation changes the glycolysis st
Externí odkaz:
https://doaj.org/article/c96e37e7330843d68090f71e60261281
Autor:
Yuhao Liu, Jiaojiao Zhu, Shenghui Zhou, Yifan Hou, Ziyan Yan, Xingkun Ao, Ping Wang, Lin Zhou, Huixi Chen, Xinxin Liang, Hua Guan, Shanshan Gao, Dafei Xie, Yongqing Gu, Ping‐Kun Zhou
Publikováno v:
MedComm, Vol 5, Iss 8, Pp n/a-n/a (2024)
Abstract Thyroid cancer incidence increases worldwide annually, primarily due to factors such as ionizing radiation (IR), iodine intake, and genetics. Papillary carcinoma of the thyroid (PTC) accounts for about 80% of thyroid cancer cases. RET/PTC1 (
Externí odkaz:
https://doaj.org/article/5f76360a4bb247c7a8426fd84949409c
Publikováno v:
MedComm, Vol 5, Iss 7, Pp n/a-n/a (2024)
Abstract The DNA‐dependent protein kinase (DNA‐PK), catalytic subunit, also known as DNA‐PKcs, is complexed with the heterodimer Ku70/Ku80 to form DNA‐PK holoenzyme, which is well recognized as initiator in the nonhomologous end joining (NHEJ
Externí odkaz:
https://doaj.org/article/78b9536866554de990089e73b83d871b
Autor:
Lihui Xuan, Zheng Xu, Jinhua Luo, Yin Wang, Yuhui Yan, Can Qu, Zuozhong Xie, Magdalena Skonieczna, Ping-Kun Zhou, Ruixue Huang
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 12, Pp 2596-2607 (2023)
Abstract Exposure to nanomicroplastics (nano-MPs) can induce lung damage. The gut microbiota is a critical modulator of the gut–lung axis. However, the mechanisms underlying these interactions have not been elucidated. This study explored the role
Externí odkaz:
https://doaj.org/article/46649b2d05554ceda3b11cdb89477b39
Autor:
Ziyan Yan, Jiaojiao Zhu, Yuhao Liu, Zhongqiu Li, Xinxin Liang, Shenghui Zhou, Yifan Hou, Huixi Chen, Lin Zhou, Ping Wang, Xingkun Ao, Shanshan Gao, Xin Huang, Ping‐Kun Zhou, Yongqing Gu
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 5, Pp n/a-n/a (2024)
Abstract Introduction Radiation‐induced pulmonary fibrosis (RIPF) is a chronic, progressive, irreversible lung interstitial disease that develops after radiotherapy. Although several previous studies have focused on the mechanism of epithelial–me
Externí odkaz:
https://doaj.org/article/d2752eac8b304b11a1bef51b72c13e9a
Autor:
Lihui Xuan, Yin Wang, Can Qu, Wensen Yi, Jingjing Yang, Huiji Pan, Jing Zhang, Cuimei Chen, Chenjun Bai, Ping-Kun Zhou, Ruixue Huang
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 275, Iss , Pp 116255- (2024)
Endogenous immune defenses provide an intrinsic barrier against external entity invasion. Microplastics in the environment, especially those at the nanoscale (nanoplastics or NPs), may pose latent health risks through direct exposure. While links bet
Externí odkaz:
https://doaj.org/article/20a9f50a4ea1468b86ce84e4c897734a
Publikováno v:
Radiation Medicine and Protection, Vol 4, Iss 2, Pp 65-69 (2023)
Obesity, hyperglycemia, hypertension, hypertriglyceridemia and low high-density lipoprotein cholesterol are the typical features of Metabolic syndrome (MetS). Exploring the risk factors would benefit for prevention control. Several studies have revea
Externí odkaz:
https://doaj.org/article/fafb6c8911cc4b02b0f86637cf46f5b1
Publikováno v:
MedComm, Vol 4, Iss 5, Pp n/a-n/a (2023)
Abstract Double‐strand break (DSB), a significant DNA damage brought on by ionizing radiation, acts as an initiating signal in tumor radiotherapy, causing cancer cells death. The two primary pathways for DNA DSB repair in mammalian cells are nonhom
Externí odkaz:
https://doaj.org/article/3eeaff1b6f974f4d87633f5c1f63752a