Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Pinelopi, Manousou"'
Autor:
Imanol Duran, Joaquim Pombo, Bin Sun, Suchira Gallage, Hiromi Kudo, Domhnall McHugh, Laura Bousset, Jose Efren Barragan Avila, Roberta Forlano, Pinelopi Manousou, Mathias Heikenwalder, Dominic J. Withers, Santiago Vernia, Robert D. Goldin, Jesús Gil
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Cellular senescence is a stress response with broad pathophysiological implications. Senotherapies can induce senescence to treat cancer or eliminate senescent cells to ameliorate ageing and age-related pathologies. However, the success of s
Externí odkaz:
https://doaj.org/article/5c897b7121a9453294556dca1837ca68
Autor:
David Sheridan, Jeremy F Cobbold, Jeremy W Tomlinson, William Alazawi, Richard Parker, Alice J Sitch, Fredrik Karpe, David Harman, Hamish Miller, Márta Korbonits, Philip N Newsome, Guruprasad Padur Aithal, Pinelopi Manousou, Wiebke Arlt, Matthew Neville, Michael Biehl
Publikováno v:
BMJ Open, Vol 14, Iss 1 (2024)
Introduction Non-alcoholic fatty liver disease (NAFLD) affects approximately one in four individuals and its prevalence continues to rise. The advanced stages of NAFLD with significant liver fibrosis are associated with adverse morbidity and mortalit
Externí odkaz:
https://doaj.org/article/c214c03f55b64cb2948ce7f6c0914dce
Autor:
Wenhao Li, David Sheridan, Stuart McPherson, William Alazawi, Kush Abeysekera, Tom Marjot, Paul Brennan, Sara Mahgoub, Tessa Cacciottolo, Theresa Hydes, Tim Hardy, Gio McGinty, Oliver Tavabie, Jennifer Cathcart, Chirantha Premathilaka, Ashis Mukhopadhya, Arshiya Bhat, Shahnaz Begum, Bashar Abushaban, Meha Bhuva, Sophie Sinclair, Damien Leith, Cullen McCulloch, Joanna Leithead, Richard Fox, Muhammad Haris Shah, Eugene Campbell, Edward Brown, Dina Mansour, Fatma Shah, Michael Allison, Jonathan Chan, Victoria Roberts, Gautham Appanna, Mandour Omer Mandour, Georgina Slee, Vicki Wong, Sreelakshmi Kotha, Katrina Pekarska, Richard Parker, Cyril Sieberhagen, Thomas Ngan, Esra Asilmaz, Hamish Miller, Jeremy Cobbold, Dom Crocombe, Manolis Tsochatzis, Sudeep Tanwar, Aruna Dias, Gurmit Singh, Swastik Agrawal, Puneet Chhabra, Amrita Gurung, Rajesh Veettil, Robin Daniel Abeles, Devnandan Chatterjee, Michael Carbonell, Zameer Mohamed, Ahmed El-Sayed, Amy Johnson, Stephen Barclay, Katherine Kelly, Joshua Munonye, Dominic Coates, Opeyemi Bamidele, Thomas Johnston, David Samuel, Belinda Ball, Rebecca Arscott-Samuel, Pamela Hams, Matthew Armstrong, Ayman Elkhol, Karanth Shailesh, Vikram Bains, Pinelopi Manousou, Tarun Gupta, Sophia Than, Esther Unitt, Victoria Gordon, Alice Wakefield, Sian Gilchrist, Ioana Cozma, Sohaib Saeed, Salman Umrani, Kathryn Olsen
Publikováno v:
JHEP Reports, Vol 5, Iss 12, Pp 100897- (2023)
Background & Aims: Non-alcoholic fatty liver disease (NAFLD) is associated with liver and cardiovascular morbidity and mortality. Recently published NAFLD Quality Standards include 11 key performance indicators (KPIs) of good clinical care. This nati
Externí odkaz:
https://doaj.org/article/bb54d49e02c042e2b9089458eef64e89
Autor:
Pei Chia Eng, Roberta Forlano, Tricia Tan, Pinelopi Manousou, Waljit S. Dhillo, Chioma Izzi-Engbeaya
Publikováno v:
JHEP Reports, Vol 5, Iss 10, Pp 100835- (2023)
Summary: Non-alcoholic fatty liver disease (NAFLD) is a major cause of liver disease worldwide, affecting up to 30% of adults. Progression to non-alcoholic steatohepatitis (NASH) is a key risk factor for cirrhosis, hepatocellular carcinoma and cardio
Externí odkaz:
https://doaj.org/article/b65ab81e2c2148f3b2f5f6de245a6c7c
Publikováno v:
Biological Imaging, Vol 3 (2023)
Non-alcoholic fatty liver disease (NAFLD) is now the leading cause of chronic liver disease, affecting approximately 30% of people worldwide. Histopathology reading of fibrosis patterns is crucial to diagnosing NAFLD. In particular, separating mild f
Externí odkaz:
https://doaj.org/article/81c943f736f04a5cb4661b69716f413e
Autor:
Stephania Guzman, Magdalena Dragan, Hyokjoon Kwon, Vanessa de Oliveira, Shivani Rao, Vrushank Bhatt, Katarzyna M. Kalemba, Ankit Shah, Vinod K. Rustgi, He Wang, Paul R. Bech, Ali Abbara, Chioma Izzi-Engbeaya, Pinelopi Manousou, Jessie Y. Guo, Grace L. Guo, Sally Radovick, Waljit S. Dhillo, Fredric E. Wondisford, Andy V. Babwah, Moshmi Bhattacharya
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 10 (2022)
Nonalcoholic fatty liver disease (NAFLD), the most common liver disease, has become a silent worldwide pandemic. The incidence of NAFLD correlates with the rise in obesity, type 2 diabetes, and metabolic syndrome. A hallmark featureof NAFLD is excess
Externí odkaz:
https://doaj.org/article/d5978c3d5db74a0d9aa1806435739a3c
Publikováno v:
Metabolites, Vol 13, Iss 4, p 536 (2023)
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of abnormal liver function tests worldwide, with an estimated prevalence ranging between 19–46% in the general population. Of note, NAFLD is also expected to become a leading cause
Externí odkaz:
https://doaj.org/article/f5f6cc51ebb1429fb169b6670be157aa
Autor:
Jian Huang, Giordano Sigon, Benjamin H. Mullish, Dan Wang, Rohini Sharma, Pinelopi Manousou, Roberta Forlano
Publikováno v:
Nutrients, Vol 15, Iss 8, p 1992 (2023)
The prevalence of Non-alcoholic fatty liver disease (NAFLD) and associated complications, such as hepatocellular carcinoma (HCC), is growing worldwide, due to the epidemics of metabolic risk factors, such as obesity and type II diabetes. Among other
Externí odkaz:
https://doaj.org/article/435ee5fcb113410f940b63f49852ff30
Autor:
Nila Jambulingam, Roberta Forlano, Benjamin Preston, Benjamin H. Mullish, Greta Portone, Yama Baheer, Michael Yee, Robert D. Goldin, Mark R. Thursz, Pinelopi Manousou
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3563 (2023)
Nonalcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease worldwide, with fibrosis stage being the main predictor for clinical outcomes. Here, we present the metabolic profile of NAFLD patients with regards to fibrosis prog
Externí odkaz:
https://doaj.org/article/9f46d9c05799466486a87c71bac4156a
Autor:
Rooshi Nathwani, Benjamin H. Mullish, David Kockerling, Roberta Forlano, Pinelopi Manousou, Ameet Dhar
Publikováno v:
European Medical Journal, Vol 4, Iss 4, Pp 105-116 (2019)
With the increasing burden of liver cirrhosis, the most advanced stage of hepatic fibrosis, there is a need to better understand the pathological processes and mechanisms to target specific treatments to reverse or cease fibrosis progression. Antivir
Externí odkaz:
https://doaj.org/article/83e421730b6d48dc8574fac161a75540