Zobrazeno 1 - 10
of 541
pro vyhledávání: '"Pin-Lan Li"'
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 12, Pp 100298- (2022)
The NOD-like receptor pyrin domain 3 (NLRP3) inflammasome is activated during atherogenesis, but how this occurs is unclear. Here, we explored the mechanisms activating and regulating NLRP3 inflammasomes via the acid sphingomyelinase (ASM)-ceramide s
Externí odkaz:
https://doaj.org/article/96c9c5b6f88f44d9b1520687c7ec07ea
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Recent studies have indicated that instant cell membrane resealing (ICMR) controls the activation of NOD-like receptor pyrin domain containing 3 (Nlrp3) inflammasomes in endothelial cells, thereby initiating and promoting vascular inflammation. It re
Externí odkaz:
https://doaj.org/article/8e292cf5d94a47d685bdcaddb0cb46fb
Autor:
Owais M. Bhat, Pin-Lan Li
Publikováno v:
Cellular Physiology and Biochemistry, Vol 55, Iss 3, Pp 277-300 (2021)
Externí odkaz:
https://doaj.org/article/34f32a92f7a7443fbf336ca0455eb062
Publikováno v:
Cellular Physiology and Biochemistry, Vol 55, Iss S4, Pp 13-34 (2021)
Externí odkaz:
https://doaj.org/article/ff653f97e70946d1a4700cb1983e558b
Publikováno v:
Redox Biology, Vol 43, Iss , Pp 102013- (2021)
The nucleotide-binding oligomerization domain-like receptor containing pyrin domain 3 (NLRP3) inflammasome in podocytes has been implicated in the initiation of glomerular inflammation during hyperhomocysteinemia (hHcy). However, the mechanism by whi
Externí odkaz:
https://doaj.org/article/4ebd7c8a3ec34c11a27e2162cb15fbe3
Publikováno v:
Cellular Physiology and Biochemistry, Vol 53, Iss 2, Pp 355-365 (2019)
Externí odkaz:
https://doaj.org/article/cf55e2d27257479da69214bd32a6a416
Publikováno v:
Kidney & Blood Pressure Research, Pp 1-20 (2019)
Elevated homocysteine (Hcy) levels have been shown to activate nucleotide-binding oligomerization domain-like receptor containing pyrin domain 3 (NLRP3) inflammasome leading to podocyte dysfunction and glomerular injury. However, it remains unclear h
Externí odkaz:
https://doaj.org/article/bc0b3fa09ea046ae81d008e1ca7faf89
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Recent studies reported that vascular endothelial cells (ECs) secrete NLR family pyrin domain-containing 3 (NLRP3) inflammasome products such as interleukin-1β (IL-1β) via extracellular vesicles (EVs) under various pathological conditions. EVs repr
Externí odkaz:
https://doaj.org/article/8bd28e9517b946fc97777ea23350536a
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
High-mobility group box 1 protein (HMGB1) has been reported to trigger lysosome destabilization causing a wide of inflammatory diseases. The present study tested whether a lysosomal enzyme, acid ceramidase (AC), plays a critical role in HMGB1-induced
Externí odkaz:
https://doaj.org/article/bdfbf6a345174c409c5322fb96adc4de
Publikováno v:
Redox Biology, Vol 16, Iss , Pp 21-31 (2018)
Short chain fatty acids (SCFAs), a family of gut microbial metabolites, have been reported to promote preservation of endothelial function and thereby exert anti-atherosclerotic action. However, the precise mechanism mediating this protective action
Externí odkaz:
https://doaj.org/article/12780a6033364363ae1a9be0a190f693