Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Pin-Ji Lei"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Cancer dissemination to lymph nodes (LN) is associated with a worse prognosis, increased incidence of distant metastases and reduced response to therapy. The LN microenvironment puts selective pressure on cancer cells, creating cells that can survive
Externí odkaz:
https://doaj.org/article/05caf73543d24bddbf8b829a2632ebbc
Autor:
Beck Gold, BS, Pin-Ji Lei, PhD, Sophia C. Kamran, MD, Daphne A. Haas-Kogan, MD, Idalid Franco, MD, MPH, Anthony L. Zietman, MD, Alicia C. Smart, MD, Jennifer Y. Wo, MD
Publikováno v:
Advances in Radiation Oncology, Vol 9, Iss 5, Pp 101461- (2024)
Purpose: Sexual and gender minority (SGM) individuals have an increased risk of poor health outcomes, in part due to knowledge and training gaps in health care education. This study sought to evaluate the knowledge, attitudes, and practice behaviors
Externí odkaz:
https://doaj.org/article/5818dbdb1b0748c19233478120ec1dc6
Autor:
Qing-Lan Li, Dan-Ya Wang, Lin-Gao Ju, Jie Yao, Chuan Gao, Pin-Ji Lei, Lian-Yun Li, Xiao-Lu Zhao, Min Wu
Publikováno v:
Clinical Epigenetics, Vol 11, Iss 1, Pp 1-17 (2019)
Abstract Background Activation of transcription enhancers, especially super-enhancers, is one of the critical epigenetic features of tumorigenesis. However, very few studies have systematically identified the enhancers specific in cancer tissues. Met
Externí odkaz:
https://doaj.org/article/3bcd741abdec4bf6831a7a658ceb937c
Publikováno v:
Cells, Vol 10, Iss 3, p 627 (2021)
Lymph nodes are the most common sites of metastasis in cancer patients. Nodal disease status provides great prognostic power, but how lymph node metastases should be treated is under debate. Thus, it is important to understand the mechanisms by which
Externí odkaz:
https://doaj.org/article/14a835ac59d5464bbe107fe82ee5d35a
Autor:
Jia-Dong Fan, Pin-Ji Lei, Jun-Yi Zheng, Xiang Wang, Shangze Li, Huan Liu, Yi-Lei He, Zhao-Ning Wang, Gang Wei, Xiaodong Zhang, Lian-Yun Li, Min Wu
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0116782 (2015)
Transcription regulation emerged to be one of the key mechanisms in regulating autophagy. Inhibitors of H3K9 methylation activates the expression of LC3B, as well as other autophagy-related genes, and promotes autophagy process. However, the detailed
Externí odkaz:
https://doaj.org/article/85a0522988a74db7a1164899de041c62
Autor:
Zohreh Amoozgar, Jun Ren, Nancy Wang, Patrik Andersson, Gino Ferraro, Shanmugarajan Krishnan, Pin-Ji Lei, Sonu Subudhi, Kosuke Kawaguchi, Rong En Tay, Igor Gomes-Santos, Peigen Huang, Hye-Jung Kim, Dai Fukumura, Rakesh Jain
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d472fc89ecf38f1a9b2882d5c7608313
https://doi.org/10.1136/jitc-2022-sitc2022.0907
https://doi.org/10.1136/jitc-2022-sitc2022.0907
Autor:
Pin-Ji Lei, Ethel R. Pereira, Patrik Andersson, Zohreh Amoozgar, Jan Willem Van Wijnbergen, Meghan O’Melia, Hengbo Zhou, Sampurna Chatterjee, William W. Ho, Jessica M. Posada, Ashwin Srinivasan Kumar, Satoru Morita, Charlie Chung, Ilgin Ergin, Dennis Jones, Peigen Huang, Semir Beyaz, Timothy P. Padera
SummaryTumor-draining lymph nodes are critical sites for generating tumor antigen-specific T cells and are associated with durable immune responses. However, lymph nodes are often the first site of metastasis and lymph node metastases portend worse o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e30d68cf9b4795841607f60a9d7fec9
https://doi.org/10.1101/2022.10.30.514441
https://doi.org/10.1101/2022.10.30.514441
Autor:
Zohreh Amoozgar, Jun Ren, Nancy Wang, Patrik Andersson, Gino B. Ferraro, Shanmugarajan Krishnan, Pin-Ji Lei, Sonu Subudhi, Kosuke Kawaguchi, Rong En Tay, Igor L. Gomes-Santos, Peigen Huang, Hye-Jung Kim, Dai Fukumura, Rakesh K. Jain
Glioblastoma (GBM) remains a highly aggressive and uniformly fatal primary tumor, which resists cytotoxic, targeted, antiangiogenic, and immune therapies, even when used in combination. Here we report that tumor endothelial cell dysfunction confers r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffa2ee1d70f6f44d6a743002ac2365bb
https://doi.org/10.1101/2022.09.03.506476
https://doi.org/10.1101/2022.09.03.506476
Autor:
Timothy P. Padera, Ethel R. Pereira, Hengbo Zhou, Rohin Banerji, Sue Zhang, Victoria Xiao, Zixiong Wang, Hadi Tavakoli Nia, Jan Willem Maurits van Wijnbergen, Ivy X. Chen, Peigen Huang, Cecilia Kwong, Dennis Jones, Benjamin J. Vakoc, Pin-Ji Lei
Publikováno v:
Nat Biomed Eng
Strong and durable anticancer immune responses are associated with the generation of activated cancer-specific T cells in the draining lymph nodes. However, cancer cells can colonize lymph nodes and drive tumour progression. Here, we show that lympho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7fefd7266a530a654a8fe22aded7152
https://doi.org/10.1038/s41551-021-00766-1
https://doi.org/10.1038/s41551-021-00766-1
Autor:
Pin-Ji Lei, Ethel Pereira, Patrik Andersson, Zohreh Amoozgar, Jan Willem Van Wijnbergen, Meghan J. O'Melia, Hengbo Zhou, Sampurna Chatterjee, William Wee Ho, Jessica M. Posada, Ashwin Srinivasan Kumar, Satoru Morita, Charlie Chuang, Ilgin Ergin, Dennis Jones, Peigen Huang, Semir Beyaz, Timothy P. Padera
Publikováno v:
Cancer Research. 83:1298-1298
Tumor-draining lymph nodes are critical sites for generating tumor antigen-specific T cells and are associated with durable immune responses. However, lymph nodes are often the first site of metastasis and lymph node metastases portend worse outcomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab8b0102b66bf42d0eb741d604739f28
https://doi.org/10.1158/1538-7445.am2023-1298
https://doi.org/10.1158/1538-7445.am2023-1298