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Publikováno v:
Journal of Clinical Investigation. 115:1659-1665
The pathogenesis of cachexia in patients with uremia is unknown. We tested the hypothesis that uremia-associated cachexia is caused by leptin signaling through the hypothalamic melanocortin receptor 4 (MC4-R). We performed either subtotal nephrectomy
Autor:
Wal Cheung1, Pin X. Yu1, Little, Brian M.1, Cone, Roger D.2, Marks, Daniel L.1, Mak, Robert H.1 makr@ohsu.edu
Publikováno v:
Journal of Clinical Investigation. Jun2005, Vol. 115 Issue 6, p1659-1665. 7p. 2 Charts, 3 Graphs.