Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Pin Mei Yao"'
Autor:
Bo Feng1, Pin Mei Yao1, Yankun Li1, Devlin, Cecilia M.1, Dajun Zhang1, Harding, Heather P.2, Sweeney, Michele3, Rong, James X.4, Kuriakose, George1, Fisher, Edward A.4, Marks, Andrew R.3, Ron, David2, Tabas, Ira1 iat1@columbia.edu
Publikováno v:
Nature Cell Biology. Sep2003, Vol. 5 Issue 9, p781-792. 12p.
Autor:
Yankun Li, Marie-Christine Gerbod-Giannone, Robert F. Schwabe, Richard A. Flavell, Alan R. Tall, David A. Brenner, Ira Tabas, Tracie DeVries-Seimon, Pin Mei Yao, Roger J. Davis
Publikováno v:
Journal of Biological Chemistry. 280:21763-21772
Two key features of atherosclerotic plaques that precipitate acute atherothrombotic vascular occlusion (“vulnerable plaques”) are abundant inflammatory mediators and macrophages with excess unesterified, or “free,” cholesterol (FC). Herein we
Publikováno v:
Cell Cycle. 4:309-313
The v-Abl tyrosine kinase activates several signaling pathways during transformation of bone marrow cells in mice. Because the SH2-containing inositol 5'-phosphatase (SHIP) and Downstream of tyrosine kinase 1 (Dok1) have been shown to interact with A
Autor:
Pin Mei Yao, Ira Tabas
Publikováno v:
Journal of Biological Chemistry. 276:42468-42476
Macrophage death in advanced atherosclerotic lesions leads to lesional necrosis and possibly plaque rupture and acute vascular occlusion. Among the likely causes of lesional macrophage death is intracellular accumulation of excess free cholesterol (F
Publikováno v:
Journal of Biological Chemistry. 275:35368-35376
Macrophages in atherosclerotic lesions accumulate excess free cholesterol (FC) and phospholipid. Because excess FC is toxic to macrophages, these observations may have relevance to macrophage death and necrosis in atheromata. Previous work by us show
Autor:
Ira Tabas, Pin Mei Yao
Publikováno v:
Journal of Biological Chemistry. 275:23807-23813
Macrophage death is an important feature of atherosclerosis, but the cellular mechanism for this process is largely unknown. There is increasing interest in cellular free cholesterol (FC) excess as an inducer of lesional macrophage death because macr
Publikováno v:
Journal of Biological Chemistry. 273:32000-32008
A cDNA for a novel human papain-like cysteine protease, designated cathepsin F, has been cloned from a λgt10-skeletal muscle cDNA library. The nucleotide sequence encoded a polypeptide of 302 amino acids composed of an 88-residue propeptide and a 21
Autor:
M P D'Ortho, Marie-Laure Franco-Montoya, Pin Mei Yao, Christine Clerici, Christophe Delclaux, Christophe Delacourt, Chantal Lafuma, Alain Harf
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 273:L663-L675
Type II pneumocytes are key cells of the alveolar epithelium. They lie on the alveolar basement membrane, which influences their phenotype and functions. We hypothesized that type II pneumocytes degrade basement membrane components by producing gelat
Autor:
Alain Harf, M P D'Ortho, Christophe Delclaux, Chantal Lafuma, François Lebargy, Jean-Marie Buhler, Pin Mei Yao
Publikováno v:
Journal of Biological Chemistry. 271:15580-15589
To investigate the role of human bronchial epithelial cells (HBECs) in the maintenance and remodeling of the extracellular matrix, we evaluated the expression by HBECs of 72- and 92-kDa gelatinases under basal conditions and after exposure to bacteri
Autor:
Hassan Lemjabbar, Bernard Maitre, Pin Mei Yao, Benoit Wallaert, M P D'Ortho, Chantal Lafuma, P. Gossett
Publikováno v:
Annals of the New York Academy of Sciences. 878:512-514